Protein

Protein accession
A0A6G5YLY5 [UniProt]
Representative
4Svbf
Source
UniProt (cluster: phalp2_19744)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MQINKLLTNINLTKTNNTGRIKYIVIHYVGATGGAEANCRYYASTYVGASAHYYVGFNGEIWQSVEDKNTAWHCGAKSYKHPECRNSNSIGIELCVRNKGNKADTSRDWYFEDATVTSAVQLTKELMAKYGVPASRVIRHYDVTGKICPNPYVYNHTKHTWNDFKAQISGGTPATNAPTPTVSTSWQAVGTATCGGSTVNVRSTPNGTKLFTLDKGNRFEVDGQTSGSWTRIKANGQIGWMATQYVNLDQPVVSTPSQPSTPNISGDSYTVKKGDTLNSIAKAMGTSVSDLAKFNGISNPNNINVGQIIKKPVSNVAVTPAPQVDQKKENIKAGQIHSINYCGAEVAIDGEFGNASLKAGIKCIQQAMVMDYGVNIAVDGIWGEKSDAALSNHSVRVGESQEMVRALQINLMLRGYDPQGVDRNFGAGCQAALIQYQKDHGLTPDGIAGRNTFLSFTK
Physico‐chemical
properties
protein length:458 AA
molecular weight:49541,1 Da
isoelectric point:9,00
hydropathy:-0,41
Representative Protein Details
Accession
4Svbf
Protein name
4Svbf
Sequence length
271 AA
Molecular weight
28850,35340 Da
Isoelectric point
9,20623
Sequence
MAKYGVPADHVIRHYDVTGKICPNPYVYNHTKHTWQDFKAQISGQQSIPTPQPAQASAWKPMGTATCGGNSVRVRQSPGGAILLSLNKGNRFEVDGQTSGSWTRVKVQSIIGWMATQYVIPDKVQTVQPAQAAQSVPATNNPIVRDGQIHCNNFCNAGLKEDGIRGAATVRGGVMVLQQAANMDYGVGLKVDGIPGAKTDAALSGHTVRIGESQEMVRALQILLMLRGYNPNGVDGSFGAGCDAAVRQYQSAHGLTVDGIAGYNTFKSLIS
Other Proteins in cluster: phalp2_19744
Total (incl. this protein): 2 Avg length: 364,5 Avg pI: 9,10
Protein ID Length (AA) pI
4Svbf 271 9,20623
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36746
6AI9B
 16 37,2% 274 2.021E-44
2 phalp2_6572
19cas
 2 29,5% 257 1.289E-16
3 phalp2_13250
366VA
 3 28,3% 324 4.093E-13
4 phalp2_2331
4MNkD
 32 22,6% 278 2.170E-07

Domains

Domains [InterPro]
Unannotated
Unannotated
PG_1
Representative sequence (used for alignment): 4Svbf (271 AA)
Member sequence: A0A6G5YLY5 (458 AA)
1 271 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacteriophage sp
[NCBI] 		38018 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN856077 [NCBI]
CDS location
range 11748 -> 13124
strand +
CDS
ATGCAGATAAATAAATTATTGACAAATATCAATTTAACAAAAACTAACAATACAGGACGTATCAAGTACATTGTTATCCACTATGTGGGTGCTACAGGTGGGGCTGAGGCGAATTGTCGCTATTATGCTTCTACTTATGTTGGTGCGTCTGCTCATTATTATGTCGGCTTTAACGGTGAAATATGGCAGTCTGTGGAAGATAAAAATACTGCATGGCATTGTGGAGCTAAGAGCTATAAGCATCCAGAATGTCGTAATAGTAACTCCATTGGAATTGAATTGTGTGTGAGGAATAAAGGTAACAAAGCCGACACCAGTAGGGATTGGTATTTTGAAGATGCTACAGTCACTAGTGCAGTACAGCTGACTAAGGAACTGATGGCTAAGTATGGAGTACCGGCAAGCCGTGTAATTCGTCACTATGATGTTACCGGAAAAATCTGTCCGAATCCATATGTATATAATCATACAAAACATACGTGGAATGATTTTAAGGCTCAGATCAGCGGTGGAACACCTGCTACCAACGCTCCAACACCAACAGTGTCTACATCATGGCAAGCTGTGGGAACGGCTACATGTGGGGGAAGTACTGTCAATGTAAGATCTACGCCGAATGGGACTAAACTTTTCACCTTAGACAAAGGTAATCGTTTTGAAGTTGATGGACAGACTAGCGGCTCATGGACTCGTATTAAGGCTAATGGACAAATAGGATGGATGGCTACACAATATGTCAATCTTGATCAACCTGTCGTTTCTACCCCCTCTCAACCATCCACACCGAATATCTCTGGTGATTCTTATACGGTGAAAAAAGGTGATACTCTTAATTCTATTGCCAAAGCTATGGGAACAAGCGTTAGCGATCTCGCAAAATTCAACGGAATTTCGAATCCAAATAATATCAATGTAGGACAGATTATTAAGAAACCAGTGTCGAATGTTGCTGTTACTCCTGCTCCTCAAGTGGATCAGAAGAAAGAAAATATAAAAGCTGGACAGATACATAGTATCAATTATTGTGGTGCAGAAGTTGCTATTGATGGTGAGTTCGGAAATGCAAGTCTCAAAGCTGGAATTAAATGTATTCAGCAAGCTATGGTTATGGACTATGGTGTCAATATCGCTGTAGATGGTATATGGGGCGAAAAGTCAGATGCTGCTCTTAGCAACCATTCTGTTCGTGTCGGAGAATCTCAGGAAATGGTGCGTGCGCTACAGATTAACCTTATGCTCAGAGGTTATGACCCTCAAGGTGTTGATCGTAATTTCGGCGCGGGATGTCAGGCTGCATTAATCCAATATCAGAAAGATCATGGTTTAACACCTGATGGTATCGCTGGGCGTAATACATTCTTAAGTTTCACAAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0009254 peptidoglycan turnover biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4Svbf) rather than this protein.
PDB ID
4Svbf
Method AlphaFoldv2
Resolution 82.66
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50