Protein

Protein accession
A0A6G5YLG3 [UniProt]
Representative
86QY9
Source
UniProt (cluster: phalp2_16965)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNTFEIAAEAIKKFEGFVSHPYKDSRGIYTIGYGTTVYPTGHKVTKNDKNITEATATYYLCVHLTSLERELGKMTNWDMLNKNQMAALLSLAYNVGCSSLRNGSIAVYLTRKEFDKVPNTILKYNKVRVNGKLQVSKGLVNRRKAEVELYNTPVESV
Physico‐chemical
properties
protein length:157 AA
molecular weight:17707,2 Da
isoelectric point:9,45
hydropathy:-0,36
Representative Protein Details
Accession
86QY9
Protein name
86QY9
Sequence length
236 AA
Molecular weight
25825,86320 Da
Isoelectric point
8,20710
Sequence
MNDHLKTSAAGLELIAKWEGCVLKPYKDIAGLRTIGFGHLIKPGENFPDGIAITREKALELLAKDVEICENAIKKHIKVLLNQNQFDALVSFGFNCGVGVYINSGVAVAVNSGQFDKVPEKLQEWSKARVNGTLQIVIGLLNRRKHEAEVFMKPVDGVPMCDPDPIIKWTKELLVEVQTNLKKLGLYALKVDGIWGPGTSNAIVTFAKDADVTLMNPHLGVPTSLLQLLRDKTASC
Other Proteins in cluster: phalp2_16965
Total (incl. this protein): 61 Avg length: 235,1 Avg pI: 8,54
Protein ID Length (AA) pI
86QY9 236 8,20710
14nxT 244 6,82974
155Qo 231 9,00747
15d7Q 229 6,59954
161E2 231 5,66255
164j7 239 8,91483
17It3 200 5,19943
17UBP 262 7,01231
17XEX 233 9,09663
18Dm6 232 9,02939
19TpD 229 8,89137
1PgN1 232 9,34503
1RbgH 231 9,15711
1XQj3 230 8,54769
1XREz 231 9,03397
1XUU7 240 9,31447
1XWUI 232 9,36095
1XXzV 230 9,14724
1hfZ6 233 9,14138
1iyD8 230 9,15672
1pcZx 239 9,14395
2VIZh 228 9,38552
2d1mk 255 8,78274
2hMjg 194 8,74883
2hXK1 240 8,98414
2hzWI 234 9,15678
2itzq 257 9,04519
2iz4N 239 4,92632
2jhKE 244 8,67811
31nft 260 9,03906
37jqN 238 9,02237
3VVAt 232 9,44135
483pA 199 8,62182
4AioK 249 9,02121
4BZp2 241 9,03352
4DNCI 225 9,44528
4Dyqe 267 6,18325
4FUm3 258 7,83860
4NH70 229 9,32008
4gMnI 223 6,90846
4o6b7 250 9,21410
4rp0z 229 8,99149
4rrZr 235 8,55162
4yVI1 266 6,92273
4zSJ0 230 9,28185
5Dhq2 228 9,60439
5DiLw 243 9,18399
5Enws 237 9,19314
5j5N1 234 8,98407
5uGZB 234 9,35960
6KyWk 221 9,86684
6L2Nh 239 9,03339
6T7zT 320 9,74080
6Vgo6 204 8,31076
8bv2q 255 8,46220
C8qh 231 8,30928
STNS 231 9,05305
ds2s 232 8,98659
iX3Z 233 7,68585
mHgI 229 5,43696
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_40206
2iAUy
 7 40,0% 207 2.828E-53
2 phalp2_6830
8n5Jv
 121 42,5% 148 5.298E-53
3 phalp2_38866
1Mo76
 29 33,6% 235 1.097E-50
4 phalp2_26378
1q5mp
 207 40,6% 160 9.849E-50
5 phalp2_28113
7zmZV
 50 38,2% 157 1.655E-48
6 phalp2_34307
3A2Hz
 178 36,5% 235 3.097E-48
7 phalp2_32792
2snIK
 45 43,2% 148 4.238E-48
8 phalp2_33221
5jbqV
 447 39,8% 153 7.931E-48
9 phalp2_2632
6RhYr
 14867 42,4% 153 5.198E-47
10 phalp2_4451
31DIk
 4919 42,0% 150 1.631E-45

Domains

Domains [InterPro]
GH24
Unannotated
Representative sequence (used for alignment): 86QY9 (236 AA)
Member sequence: A0A6G5YLG3 (157 AA)
1 236 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Caudoviricetes sp
[NCBI] 		2832643 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN856096 [NCBI]
CDS location
range 56918 -> 57391
strand -
CDS
ATGAACACATTTGAGATAGCGGCGGAAGCTATAAAAAAATTTGAAGGTTTTGTTTCTCACCCTTATAAAGATAGCAGAGGTATATATACAATTGGTTATGGCACTACTGTATATCCAACAGGGCATAAAGTAACCAAAAATGATAAAAATATCACAGAAGCGACAGCTACTTATTATTTATGCGTGCATCTTACTAGTTTGGAACGCGAATTGGGAAAGATGACTAACTGGGACATGTTAAACAAGAACCAGATGGCGGCATTATTGAGTTTGGCTTATAATGTTGGGTGTTCTAGTCTACGAAATGGGTCTATTGCTGTGTATCTTACACGTAAAGAATTTGATAAGGTTCCAAATACAATTTTAAAATATAATAAAGTTAGAGTTAATGGTAAGCTTCAAGTAAGTAAGGGTCTTGTAAATAGACGTAAGGCTGAAGTAGAATTATATAACACTCCTGTCGAAAGCGTATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (86QY9) rather than this protein.
PDB ID
86QY9
Method AlphaFoldv2
Resolution 92.63
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50