Protein

Protein accession
A0A6G5YJZ1 [UniProt]
Representative
5RffS
Source
UniProt (cluster: phalp2_13670)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKYKLNKSIRRIGLVIATVIVTMAMAIPANAANMIDISDWQRGINVTTTGADIVVVKATESTTYVNTDCDRVVQQALAAGKGVGVYHFADTRNNPTAEADYFVRQTQGYIGKGIVPILDWEPAGPANVPWALTWLNRVESRWGAKPIIYMNQNTENSYDWSPVVRQDYGLWIAAYTLGYQPIYGFHPPSAQPIMKHWPFAVAWQYTSSGRVNGWTGNVDLSVVYGSIDTWRAYASGTGTIPAPPYPPKVTTPSAPSVSGTDEQLADRVIRGEFGTIPQRQALLGNRFAAVQAIVNQRLNGGAGSSGACVVVARGDSLSSIAGKLGTSWQNLSGYRSGNPNRIYPGERICTKTGSGPVSTGSGHRVVAGESLWAIYGSGWQAAAARNGIGAPYTIYPGQTLR
Physico‐chemical
properties
protein length:401 AA
molecular weight:43148,2 Da
isoelectric point:9,44
hydropathy:-0,18
Representative Protein Details
Accession
5RffS
Protein name
5RffS
Sequence length
222 AA
Molecular weight
24208,54390 Da
Isoelectric point
5,18334
Sequence
VRARWNTIPIIYMNQSTENSYDWSPLVQRNVGLWVAAYTLGYTPIYGFNPPSRQPVLQNWPFAVAWQYTSSGHVNGWSGNLDLSVVYGDLETWYAYAGSRPDGTVNPTPAPEPAPEPTPQPSTGSCGPDCLVIQSGQYVSMFWPDWWNVSVPSGNPNRVFPGDTVCHNGGAASAGNGGRTVTVRPDDTLSGIGARLGINWTQLTGYRSGNPSLIYPGEILHY
Other Proteins in cluster: phalp2_13670
Total (incl. this protein): 11 Avg length: 362,9 Avg pI: 8,55
Protein ID Length (AA) pI
5RffS 222 5,18334
21FZK 189 4,42596
A0A6G6XZK0 402 9,49415
A0A6G6Y007 402 9,49415
A0A6G6Y0X8 414 8,96808
A0A6G5Y1H6 404 9,18947
A0A6G5Y1R5 402 9,61657
A0A6G5Y247 404 9,18947
A0A6G5YMX2 400 9,47597
A0A8S5N7X6 352 9,59059
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_22096
5ZSom
 2292 30,0% 253 1.769E-31
2 phalp2_9153
6wSxJ
 7 31,6% 234 8.990E-29
3 phalp2_7683
6E7Ka
 26 32,0% 231 2.128E-25
4 phalp2_9283
7cTgF
 101 29,5% 227 1.044E-22
5 phalp2_28052
75Rgb
 8 29,6% 162 1.686E-21
6 phalp2_25966
6D89f
 1 26,9% 234 3.126E-21
7 phalp2_12160
6ljWQ
 2 23,8% 168 2.782E-11
8 phalp2_5680
4CMV3
 1 23,4% 188 3.645E-08
9 phalp2_17221
3xRQT
 3 21,9% 155 2.281E-06

Domains

Domains [InterPro]
Unannotated
Unannotated
Unannotated
Representative sequence (used for alignment): 5RffS (222 AA)
Member sequence: A0A6G5YJZ1 (401 AA)
1 222 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacteriophage sp
[NCBI] 		38018 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN856054 [NCBI]
CDS location
range 19336 -> 20541
strand +
CDS
ATGAAGTACAAACTCAATAAGTCCATCCGACGAATCGGACTAGTGATAGCCACTGTGATTGTCACTATGGCTATGGCTATTCCGGCAAATGCAGCCAATATGATAGACATAAGCGACTGGCAACGTGGTATCAATGTCACGACCACCGGCGCGGATATCGTCGTGGTCAAAGCCACAGAGAGCACGACCTATGTCAATACGGACTGTGACCGCGTTGTACAACAAGCTCTAGCTGCCGGTAAGGGTGTCGGTGTCTATCATTTTGCCGATACACGTAATAACCCAACAGCTGAGGCAGACTATTTTGTCCGGCAGACCCAAGGGTATATAGGTAAGGGTATCGTTCCTATTCTCGACTGGGAGCCAGCCGGTCCGGCTAACGTCCCCTGGGCTTTAACTTGGCTTAACCGCGTCGAATCAAGGTGGGGAGCCAAACCAATCATCTACATGAACCAGAATACTGAAAACTCTTATGATTGGTCGCCTGTAGTCCGGCAAGATTACGGTCTATGGATAGCTGCGTACACTCTAGGCTACCAGCCCATCTACGGTTTTCACCCGCCAAGTGCTCAGCCAATCATGAAACACTGGCCTTTCGCCGTCGCATGGCAATACACCAGCTCTGGCCGTGTAAACGGGTGGACTGGTAACGTCGATTTGAGCGTCGTCTATGGGTCTATCGATACTTGGCGAGCCTATGCCAGTGGTACGGGCACTATCCCGGCACCACCATACCCGCCTAAAGTCACTACCCCGTCAGCACCGTCAGTCAGCGGAACTGATGAACAACTGGCTGACCGTGTGATTCGTGGAGAATTTGGTACTATACCACAGCGCCAAGCGCTGCTAGGGAATCGCTTTGCTGCTGTGCAAGCCATTGTTAATCAGCGGCTTAATGGTGGCGCCGGGTCTAGTGGTGCTTGCGTTGTGGTGGCTCGTGGTGACTCGCTTAGCAGTATCGCTGGCAAGCTCGGCACGTCATGGCAGAACTTATCCGGATATCGGTCTGGTAACCCGAACAGAATCTATCCGGGTGAGCGTATCTGCACAAAGACCGGTAGTGGTCCCGTCTCTACTGGGTCTGGGCACCGTGTGGTAGCTGGTGAGAGTCTTTGGGCTATCTATGGGTCTGGTTGGCAAGCAGCAGCAGCCCGAAACGGTATTGGGGCGCCGTATACGATTTATCCTGGGCAGACTCTCAGGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5RffS) rather than this protein.
PDB ID
5RffS
Method AlphaFoldv2
Resolution 77.51
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50