Protein

Protein accession
A0A6G5YHT6 [UniProt]
Representative
7qQCo
Source
UniProt (cluster: phalp2_10050)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MTVSGLATPYGFQDFPNYTEGRSAVVNKIVIHHMATTDYDSVPRIWKTREASAHYGIGQDGQIRAYVDEDNTAWHAGQWSANSSSIGIEHANMTGSPDWGIAQATIDASAKLVADIAQRYGFGQVVPYKNLFPHSEFYSTACPGQLKDKLQEIADKANDILTGGNGNVTTQSAPESSQAPKVDNRSAAIKEFQDKWKNRWALRGNFRIRTCQMQYGMYQVLTDDLNVEPNSWFYNGIPTGLLEDVSDPQVRSFEDGAIVRFKDDVNFGTIDEYDINTNSIGILFTGYKDMIWFDADKFLAHA
Physico‐chemical
properties
protein length:302 AA
molecular weight:33676,9 Da
isoelectric point:4,97
hydropathy:-0,48
Representative Protein Details
Accession
7qQCo
Protein name
7qQCo
Sequence length
297 AA
Molecular weight
32659,37000 Da
Isoelectric point
9,35722
Sequence
MTVSKLATPCMFQNFGAKRWWDGRSQKITTIVVHHAATTNFGAMPSVWRDREASAHYGIGQNGEIRAYVDEDNTAWHCGNGNAYSIGIECTNTSGEPNWGVSNATVDALVKLIQEIQSRRGKLQIVGHRDVPSNSTVCPGPSLYPRLQEIRNRVNSGSTTSTPTPSKPTNVLTAGAGYSVLSDGKGNHAHLDEYGPTGSKLKVRGWHIANYKHEFIILIDRVTGKEVIRQLAKGVARPDVNKAYNTKGNVGFDVMFDLKPLKGKSIVVLMRATNDPDGNTKGGHQDFTETRWYHDIK
Other Proteins in cluster: phalp2_10050
Total (incl. this protein): 2 Avg length: 299,5 Avg pI: 7,16
Protein ID Length (AA) pI
7qQCo 297 9,35722
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_10524
86QiV
 42 36,2% 298 1.771E-41
2 phalp2_1214
8MrbY
 36 31,5% 276 7.757E-26
3 phalp2_29674
8k36v
 96 28,1% 252 4.737E-20
4 phalp2_31265
8lSNT
 54 28,2% 312 2.550E-17
5 phalp2_7262
3WyJ7
 1 30,6% 212 5.346E-15
6 phalp2_14952
lBvU
 3 27,0% 274 9.655E-15
7 phalp2_1359
1dk8I
 5 27,8% 205 4.437E-13
8 phalp2_30077
2WEC1
 850 24,5% 318 1.543E-09
9 phalp2_2602
6IbUl
 53 25,3% 221 3.379E-04

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 7qQCo (297 AA)
Member sequence: A0A6G5YHT6 (302 AA)
1 297 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Caudoviricetes sp
[NCBI] 		2832643 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN856005 [NCBI]
CDS location
range 16308 -> 17216
strand -
CDS
ATGACAGTTTCAGGATTAGCAACGCCTTATGGCTTTCAGGACTTCCCAAATTATACGGAAGGGCGTAGCGCAGTAGTTAATAAGATTGTGATTCACCACATGGCCACAACGGACTATGATTCAGTCCCACGTATCTGGAAGACACGAGAAGCTTCGGCACACTATGGTATCGGTCAAGATGGGCAAATCCGTGCATACGTTGATGAAGATAATACAGCATGGCACGCTGGACAGTGGTCAGCTAACTCATCTTCAATTGGTATTGAGCACGCTAACATGACTGGTAGCCCTGATTGGGGTATTGCACAGGCAACCATTGATGCTTCTGCTAAGTTGGTCGCAGATATTGCGCAACGTTATGGATTCGGCCAGGTAGTACCATACAAGAACCTGTTCCCCCATTCAGAGTTTTACAGTACTGCCTGCCCAGGCCAGTTAAAGGACAAGCTGCAAGAAATTGCAGATAAGGCTAACGATATTCTGACTGGAGGTAATGGAAACGTTACTACACAATCAGCTCCAGAATCATCTCAAGCACCAAAGGTCGATAACCGTTCGGCTGCTATTAAGGAGTTCCAAGACAAATGGAAGAACCGCTGGGCATTGCGCGGTAATTTCCGCATTCGTACATGCCAAATGCAATATGGGATGTATCAGGTACTAACTGATGACTTGAATGTTGAACCTAATTCTTGGTTCTACAATGGTATCCCTACTGGTTTGTTGGAAGACGTTTCTGACCCACAAGTCCGTTCCTTTGAAGACGGAGCTATTGTTCGATTTAAGGACGATGTCAATTTTGGAACGATTGACGAATATGACATCAACACAAATTCAATCGGTATCTTGTTCACTGGCTACAAAGATATGATTTGGTTTGATGCTGATAAGTTCTTAGCTCATGCCTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0009254 peptidoglycan turnover biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7qQCo) rather than this protein.
PDB ID
7qQCo
Method AlphaFoldv2
Resolution 91.90
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50