Protein

Protein accession
A0A6G5YDF9 [UniProt]
Representative
3yWnL
Source
UniProt (cluster: phalp2_30164)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNGIDISSAQAGLDLSKIPFDFAIVKATQGTNYTNPCCVGHVDQAASLGKLVGVYHYIGGGNAKGEAQFFVDSIRNWIGKHIIAVDWEQYQNSAWGDQSYLETVVSEVIRLTGVHPLIYGQQSVYGTIAAVGKKYDCGLWVAQYADMNATGYQDSPWNEGAYACAVRQYSSVGRLPGYGSNLDLDKFYGNANQWNAYAHNTGGNTPPPAPPAPPAPPANTGTTYVVQPGDTLWGIAQKYGTTYQHLADINNIREPDKINAGQIIHIDTAPLPNNGANATYIVQPGDNLTVIAQKFGTTVNDLAAINGIPHDRLDYIQAGQTLKVPGQSSRTYVVKPGDTLSQIAARFGMDYHHLADINGIKEPDKIQAGWILHY
Physico‐chemical
properties
protein length:374 AA
molecular weight:40414,6 Da
isoelectric point:5,71
hydropathy:-0,30
Representative Protein Details
Accession
3yWnL
Protein name
3yWnL
Sequence length
555 AA
Molecular weight
60081,67750 Da
Isoelectric point
5,00788
Sequence
MALNGIDIASYQAGINLDAVPFDFVIVKATEGTNYVNPYCSTWVEKALAMEKCVGIYHYINGVGATAEADYFYNNCYNWVGKVVFCLDWEQGGNSAWGNESYLKQMAQRLMDKTGIPPIIYVQQSRMSAVKPVANALNCGLWIAQYANMNATGYQSSPWNEGSYFCAIRQYSSCGRLSGYSGNLDLNKFYGDTVAWGKYANPNRTSGSTNQPEVNDTPIAPVGELSVPEKAAQIMEHLCTHNAHGYSQPNRAGIGTGGDKGETITLSDGSTVVISSGDRDCSSAVIECYAAQGIDCGGASYTGNMKSCMTSTGNFEALPASTWQNPKRGDILLNSAKHTVLALGNGKVGSFSRSENHSIHGNRGDQDGGESVITSLYNGNWDCVLRYIGPNASTNGSSSSDSGANSTQVEGFSGKYECQENGVNVRYAPSTSAQIDESRKFNKGDTIILDNWVYVADGYYWGRYNISDTEVRYIAIGEVEETLFEKISSSSYNVQITTNTLNVRSGPGTNYYITTTVHDGEVYTIVDESSGEGASKWGKLISGAGWISLDYVKRL
Other Proteins in cluster: phalp2_30164
Total (incl. this protein): 3 Avg length: 435,0 Avg pI: 5,58
Protein ID Length (AA) pI
3yWnL 555 5,00788
A0A6G5XVB1 376 6,03644
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_4039
19nTK
 10 37,4% 422 7.504E-62
2 phalp2_37225
24mkV
 7 34,8% 431 2.130E-52
3 phalp2_34333
3TFvI
 9 33,4% 406 2.534E-43
4 phalp2_6342
7hreA
 7 31,4% 435 3.857E-41
5 phalp2_13609
5otWQ
 1 29,9% 417 4.281E-39
6 phalp2_32938
3TLgl
 6 29,9% 424 1.118E-36
7 phalp2_5498
3ibaX
 1 22,9% 387 8.119E-10

Domains

Domains [InterPro]
GH25
Unannotated
Unannotated
SH3_3
Representative sequence (used for alignment): 3yWnL (555 AA)
Member sequence: A0A6G5YDF9 (374 AA)
1 555 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF08239

Taxonomy

  Name Taxonomy ID Lineage
Phage Caudoviricetes sp
[NCBI] 		2832643 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN855954 [NCBI]
CDS location
range 22391 -> 23515
strand +
CDS
ATGAACGGAATTGACATATCCTCGGCCCAAGCCGGGTTGGACCTCAGTAAAATACCCTTTGATTTCGCCATCGTCAAAGCGACGCAAGGCACGAACTACACAAACCCGTGTTGTGTGGGCCATGTTGACCAAGCCGCCAGCCTGGGCAAGTTGGTAGGAGTCTACCATTACATAGGCGGCGGCAACGCCAAAGGCGAGGCGCAATTCTTTGTGGACAGTATCCGCAATTGGATCGGCAAGCATATTATCGCGGTTGACTGGGAGCAGTATCAAAACTCGGCCTGGGGCGACCAGTCGTATCTTGAAACCGTCGTTTCTGAGGTTATCAGGCTCACCGGCGTTCACCCGCTGATCTACGGCCAACAAAGCGTGTACGGCACGATAGCCGCCGTTGGCAAGAAGTATGACTGCGGACTGTGGGTGGCACAGTATGCCGACATGAACGCCACCGGCTACCAGGACAGCCCTTGGAATGAGGGTGCTTACGCTTGTGCTGTTCGCCAATACTCCTCGGTGGGCAGATTGCCTGGATACGGGTCCAACCTGGACCTGGACAAGTTCTATGGGAATGCCAACCAGTGGAACGCCTACGCACATAATACTGGTGGGAATACGCCGCCGCCAGCGCCCCCCGCACCACCAGCACCACCGGCGAACACTGGCACCACGTATGTCGTGCAACCGGGAGACACCCTCTGGGGTATCGCCCAAAAATACGGGACCACTTACCAGCATTTGGCCGACATTAACAACATCAGGGAACCGGATAAGATTAATGCCGGGCAGATCATCCACATTGATACCGCGCCGTTGCCAAACAATGGGGCAAACGCCACGTATATCGTGCAACCAGGCGACAATCTTACGGTTATCGCCCAGAAATTCGGAACCACAGTGAATGATCTTGCCGCCATAAACGGCATTCCCCACGACCGTTTGGATTATATTCAGGCCGGTCAGACCTTGAAGGTCCCAGGACAGTCGAGCCGCACGTATGTTGTGAAGCCTGGCGACACCCTGTCCCAGATCGCCGCAAGGTTCGGCATGGACTATCATCATCTGGCCGACATTAACGGCATTAAGGAGCCGGATAAGATTCAGGCTGGTTGGATACTTCACTATTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3yWnL) rather than this protein.
PDB ID
3yWnL
Method AlphaFoldv2
Resolution 82.03
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50