Protein

Protein accession
A0A6G5YAM4 [UniProt]
Representative
4SuEX
Source
UniProt (cluster: phalp2_14510)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MLNVIDVSNNNGGLNVANITADGVIAKATESSNFTDSALPTFMAQSKNTSKLTGVYHFARPGDWKVQADFFLRTAKPYLNNSIIVLDYESTVVTYGGVQWALNWLDYVYKQTGIKPMIYMGLADENYYNWAPVAKKYALWVAQYNDMAPHYGFQPRNLYGSVRHFKKMTMFQYSANGRLTGYNGPLDLDVYYGPKSDWSKHQNNDTGDENKLMEWHVKVPVTAYGGFLVTKKKGATIWAAPNNDKKVGILKYNEPITILAAEHGFFKTSKGYIDPRTGVAKLNPLLDNPNIHSVIEVTGSAKGHAEAAGPITGRKFKKGNRYKAYKFSKGYLLIGSGVDRWINGQKVKIIL
Physico‐chemical
properties
protein length:351 AA
molecular weight:39225,3 Da
isoelectric point:9,52
hydropathy:-0,38
Representative Protein Details
Accession
4SuEX
Protein name
4SuEX
Sequence length
366 AA
Molecular weight
40606,23840 Da
Isoelectric point
9,54978
Sequence
MLHGIDISNWQAGFNSKAVSADFVIIQATNGLSRNAYLDYQVKHLGSKRVGLYHFATLAGSYKQEADNFIHEVKRYGLVGKAVLAVDFEAQYATQGNIGWLSHWLDYVYNVLGVRPMVYTALSSENYLSWGDIPNKAKLWVAQYNNYNPVYGYHARSMYGSTRHWKSATVFQYTGYGRLNGFAGNLDFNVFYGSGSDWDALAKGKATSSGSSTASKEEDEQNLSTWHVKVPYNVYGGCLITKSRGAIVYKSSDLKKSTGKKLKYNTNWLVYDNKDGALHVGSGQWIDSRSALLRLNGIAENGTKAVAYVTSDSLYTQNELNGGAKGIKHLPKGTRWLVHGRKGKYLMVGNEKTGKYINGSKVKISL
Other Proteins in cluster: phalp2_14510
Total (incl. this protein): 6 Avg length: 363,7 Avg pI: 7,42
Protein ID Length (AA) pI
4SuEX 366 9,54978
5MSo9 362 7,73297
6YpDi 371 5,77435
7gX0O 361 6,39179
Kztu 371 5,56973
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_7658
6ucuX
 7 27,2% 393 1.208E-69
2 phalp2_11124
5oePU
 31 28,7% 393 1.668E-64
3 phalp2_7780
7iNFi
 6 24,0% 374 5.005E-17
4 phalp2_12277
79IyY
 11 25,9% 239 3.847E-13

Domains

Domains [InterPro]
GH25
Unannotated
Representative sequence (used for alignment): 4SuEX (366 AA)
Member sequence: A0A6G5YAM4 (351 AA)
1 366 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Caudoviricetes sp
[NCBI] 		2832643 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN855822 [NCBI]
CDS location
range 429 -> 1484
strand +
CDS
ATGCTTAATGTTATTGATGTCAGCAATAATAATGGTGGACTAAATGTAGCCAATATTACAGCAGATGGTGTAATTGCCAAGGCAACAGAGAGCAGTAACTTTACTGACTCAGCGCTACCAACTTTTATGGCTCAATCAAAAAATACTAGTAAATTAACCGGTGTCTACCATTTTGCACGTCCTGGAGACTGGAAAGTTCAAGCTGATTTTTTCCTACGTACAGCAAAACCATATCTAAATAACTCTATTATCGTGCTCGACTATGAGAGTACGGTAGTAACATATGGTGGCGTGCAATGGGCACTTAATTGGCTAGATTATGTTTATAAGCAAACTGGAATTAAGCCTATGATTTACATGGGACTAGCAGACGAAAACTACTACAATTGGGCACCAGTTGCTAAAAAGTACGCACTATGGGTTGCACAATATAATGACATGGCACCACATTATGGTTTTCAGCCACGCAATCTATATGGTTCAGTTCGTCACTTTAAAAAAATGACCATGTTTCAGTATTCAGCAAACGGCCGCTTGACTGGCTATAACGGCCCACTAGATCTAGATGTCTATTATGGTCCAAAATCTGATTGGTCCAAGCATCAGAATAATGATACAGGAGATGAAAACAAATTAATGGAATGGCATGTTAAGGTACCAGTTACAGCATACGGTGGCTTCCTGGTGACAAAGAAAAAAGGTGCAACAATCTGGGCTGCACCAAATAATGATAAAAAAGTCGGTATTCTTAAATATAATGAGCCAATCACTATTTTGGCAGCAGAGCATGGTTTTTTTAAAACAAGTAAAGGATACATTGATCCACGTACTGGTGTAGCCAAACTCAATCCATTGTTGGATAATCCAAATATCCACTCCGTAATTGAAGTAACTGGTAGTGCCAAAGGTCATGCTGAAGCAGCTGGACCTATTACTGGCCGCAAATTCAAAAAGGGTAATAGATACAAAGCATACAAGTTCAGCAAAGGCTATCTATTAATTGGTAGCGGTGTTGATCGTTGGATTAATGGTCAAAAAGTCAAAATCATTCTATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4SuEX) rather than this protein.
PDB ID
4SuEX
Method AlphaFoldv2
Resolution 88.96
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50