Protein

Protein accession
A0A6G5Y9H2 [UniProt]
Representative
3QBcV
Source
UniProt (cluster: phalp2_4532)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRVSNVNAIKEHEGLRLVAYLDSVGVWTIGYGDTGPDVVEGLVITKEEAEERLRKRLREFEGYVLKYVRVGLTQNQFDALVSLVYNIGPTNFSSSTLLKKLNAGDYQGAADQFLVWNKGRVNGKLVVIKGLSNRRAAERQLFMS
Physico‐chemical
properties
protein length:144 AA
molecular weight:16136,3 Da
isoelectric point:9,39
hydropathy:-0,20
Representative Protein Details
Accession
3QBcV
Protein name
3QBcV
Sequence length
218 AA
Molecular weight
23937,13100 Da
Isoelectric point
5,08399
Sequence
MNPIWTILKDVLSMFAPGLQEKIEVGAKIIPFPTKYKPEDDAEQPEEQTSEPAGSTVEPEKGTNLSEKLIVPIVLRRTINDEGCTLIKKFEGLCTKAYKDVIGVVTIGYGSTGEHVQMGMEISEQEAEDLLKLDLERFEKGVEKLVTVALTDNQFAALVSFSFNCGLGNLKSSTLLRKLNAGDYSGAAMEFQKWNKAGGKVYPGLTKRRAAESELFGN
Other Proteins in cluster: phalp2_4532
Total (incl. this protein): 9 Avg length: 197,4 Avg pI: 7,02
Protein ID Length (AA) pI
3QBcV 218 5,08399
1OYZy 227 9,37997
4sbOX 197 5,08404
59MWL 199 8,87370
6zkMM 197 5,29605
89k5p 197 5,17351
M4W600 254 5,19226
A0A2P9FI97 144 9,71295
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28113
7zmZV
 50 60,1% 143 1.223E-58
2 phalp2_6830
8n5Jv
 121 56,1% 155 9.012E-56
3 phalp2_2632
6RhYr
 14867 59,2% 140 2.314E-55
4 phalp2_2498
5GMvl
 297 59,7% 139 3.917E-54
5 phalp2_33221
5jbqV
 447 58,5% 140 9.072E-53
6 phalp2_4451
31DIk
 4919 57,9% 145 1.701E-52
7 phalp2_3550
4CbTI
 96 50,3% 153 2.875E-51
8 phalp2_15045
7iQxx
 18 56,2% 135 2.335E-49
9 phalp2_17663
6R9yG
 6 59,3% 145 1.122E-48
10 phalp2_6905
2wnW6
 22 54,0% 137 1.536E-48

Domains

Domains [InterPro]
GH24
Representative sequence (used for alignment): 3QBcV (218 AA)
Member sequence: A0A6G5Y9H2 (144 AA)
1 218 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacteriophage sp
[NCBI] 		38018 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN855795 [NCBI]
CDS location
range 11085 -> 11519
strand +
CDS
ATGCGAGTGAGTAATGTAAACGCCATTAAGGAGCACGAGGGGCTACGTCTGGTAGCCTACCTCGATTCTGTAGGTGTGTGGACGATTGGCTATGGTGACACAGGCCCTGATGTAGTTGAGGGCCTAGTCATTACCAAGGAGGAAGCTGAGGAACGCCTCAGGAAGCGTCTCAGAGAGTTTGAGGGCTATGTCTTGAAGTATGTTCGGGTTGGTTTGACACAGAACCAGTTCGACGCCTTAGTAAGTTTGGTCTATAACATTGGACCCACTAACTTCTCCAGCTCTACACTTCTCAAGAAGCTGAACGCTGGTGACTACCAAGGGGCTGCTGACCAGTTCCTTGTATGGAACAAAGGGCGTGTCAATGGCAAGCTTGTAGTGATCAAAGGACTATCTAACCGAAGGGCTGCGGAAAGACAATTATTTATGAGTTGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3QBcV) rather than this protein.
PDB ID
3QBcV
Method AlphaFoldv2
Resolution 77.27
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50