Protein

Protein accession
A0A6G5Y7Q1 [UniProt]
Representative
6wAjV
Source
UniProt (cluster: phalp2_36076)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTLKVIDIASYQSVEAAADPNAAGVIIKATQGNYYVNPKCNAQYALAKKSGKLLGLYHYAGGGNPEVEAQYFIRNIKNYVGEATLWLDWESGENPSWGDTGWCLRFVNEVYKITGVYPGIYIQASSVWQAASCADKSALWIAGYPTRGAGWDVPAFIYSTAPWKTYTIWQFTDGGGLDKNIANLDAAGWKALAKGSKQDAKPTPTPTPSPAPGKYSTAGKNLEAMAGDVQAGNVGDGDTRKNNLGKYYIGVQAIVNHRVTGKDATDVLVGETKKGVYGNGDGRKNLLGNYYKSVQAKIDGAAPTAATRSYTVQNGDTLSGIGSKLGISYLTLAAKNGIKAPYTIFPGQKIKY
Physico‐chemical
properties
protein length:352 AA
molecular weight:37600,9 Da
isoelectric point:9,19
hydropathy:-0,34
Representative Protein Details
Accession
6wAjV
Protein name
6wAjV
Sequence length
388 AA
Molecular weight
42934,53330 Da
Isoelectric point
4,98628
Sequence
MLRGIDVSSHDGWSNGRFGKQNTETAYGESDFVIAKATQGTGYVNKYCDPAIQRAKSDGKLWGFYHYAGGNDPVAEANFFYNNCKGYFGEGIPCLDWERTQNSSWGSTTWCRRFVDRIHELTGIWCMVYIQASAVGQAASCASDCALWIAGYPDNRNSWEMPTFRYGTGAWATWTLWQYTSSGELTDRNYAQLTREGWLAIAGASPSSGPAGWVYDESDADKQWYRHADGSYTTNDWELIDGEWYHFDASGWVQWGWFCDDAGKWYRLHDRHDGRFGACDSGWITDAAGDKYFASQTSGDPWGSLYTGVHVIDGERYCFADAPSCRLVRNAAYASDGKVHVADSEGRAVRGRIAQVGGKMYALGDDGAALTGAIVLQAGEDGVLKATN
Other Proteins in cluster: phalp2_36076
Total (incl. this protein): 94 Avg length: 351,4 Avg pI: 4,93
Protein ID Length (AA) pI
6wAjV 388 4,98628
11t3b 354 4,54152
19ap3 385 8,57283
1HIQR 354 4,55021
1HIe6 354 4,65747
1HJWT 354 4,64689
1cxO4 354 4,69742
1errM 340 8,92624
1kQhS 354 4,56260
1lGOu 315 4,57397
1lHFV 354 4,60307
2VcIM 348 5,76799
2blgF 356 5,03181
3c4tK 361 4,72982
5HE4W 304 5,37381
5KDtm 354 4,64525
5NmUe 354 4,55021
5VObk 345 9,11675
5Wx6F 375 4,99390
5YvR2 361 4,57442
5oGKG 386 6,31267
5tGGu 304 5,54853
648bk 361 4,69293
65JBY 356 4,98793
66yM8 354 4,59108
69M3Y 305 4,80940
6ZIsl 315 4,62041
6ZgXt 354 4,63615
6ZtlK 312 4,42636
6bui6 354 4,55214
6cvj8 354 4,54152
6gOGi 354 4,58034
6i5Cd 355 9,25007
6if8U 354 4,56249
6r4OR 354 4,63615
6vylR 361 4,66304
70aaY 354 4,64689
70jqp 361 4,67134
7Bz6c 361 4,65605
7OTwC 361 4,74312
7OozC 354 4,51383
7XtRr 352 5,11820
7pxVW 377 5,12576
84nqq 354 4,50088
853NB 361 4,74977
88UDi 361 4,63996
8HHoI 361 4,63610
8bpEb 354 4,64525
8cafm 361 4,71948
8hOtP 354 4,63615
8hjv0 362 4,61398
8mKop 304 4,65292
8nd4A 312 4,57869
8ontc 354 4,51383
8qUys 354 4,55021
C72K 354 4,53970
Cqdm 297 4,49468
DEzl 362 4,64053
Dvj1 361 4,57261
EIs2 354 4,60176
ESuV 354 4,64689
Hu9b 354 4,60307
HwJD 354 4,64689
K8sG 354 4,55209
K9w7 361 4,63041
N9mg 354 4,56948
NETU 362 4,86248
NJrC 354 4,63615
Ng2Z 317 4,47962
NoiC 354 4,61575
O5oC 361 4,80513
OI3F 354 4,44290
OSEa 354 4,47825
OpgD 354 4,71311
OqIf 354 4,65570
oGLX 354 4,64689
oIrg 354 4,52907
oNrW 354 4,63865
oP6V 319 4,46672
oPf1 319 4,50417
p5yH 375 4,95530
p7qR 354 4,59256
p7yq 354 4,56260
qkbR 362 4,79502
wXaK 354 4,56249
x5ng 363 4,64286
xBn2 358 4,62262
ynRT 354 4,51219
ynSa 354 4,51219
yoOF 354 4,51383
yobn 354 4,60307
yokL 361 4,72488
A0A6G5Y8S0 347 5,46827
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12276
79roT
 46 32,5% 323 5.168E-51
2 phalp2_36209
7jVrq
 19 28,4% 376 6.147E-46
3 phalp2_38194
7g15T
 1 24,1% 393 1.238E-33
4 phalp2_40149
8qW5P
 4 26,0% 299 9.107E-28
5 phalp2_25079
1fQ0R
 67 27,8% 251 4.578E-19
6 phalp2_6287
6QxUm
 6 25,9% 262 6.293E-17

Domains

Domains [InterPro]
GH25
Unannotated
Representative sequence (used for alignment): 6wAjV (388 AA)
Member sequence: A0A6G5Y7Q1 (352 AA)
1 388 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Caudoviricetes sp
[NCBI] 		2832643 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN855775 [NCBI]
CDS location
range 30880 -> 31938
strand -
CDS
ATGACCTTAAAAGTCATTGATATTGCGTCATATCAATCAGTAGAAGCTGCTGCTGATCCAAATGCGGCTGGCGTGATTATTAAAGCTACTCAAGGTAACTACTATGTCAACCCTAAGTGTAATGCTCAGTATGCCTTAGCTAAAAAGTCAGGTAAACTATTAGGTCTTTATCACTATGCTGGTGGCGGTAATCCTGAAGTAGAAGCTCAGTACTTCATTCGCAACATTAAGAACTATGTAGGTGAAGCAACCTTATGGCTTGACTGGGAATCTGGTGAAAATCCGTCATGGGGCGACACAGGTTGGTGTTTACGCTTTGTAAATGAAGTGTATAAGATCACTGGTGTCTATCCAGGTATCTATATTCAAGCTTCGTCTGTTTGGCAAGCTGCTTCATGTGCTGATAAGTCTGCATTATGGATTGCGGGTTATCCAACTCGTGGTGCAGGATGGGATGTTCCAGCATTTATCTATAGTACAGCCCCTTGGAAGACCTATACAATCTGGCAATTTACAGATGGTGGCGGTCTAGACAAGAACATTGCAAACTTAGATGCTGCTGGTTGGAAAGCTTTGGCAAAAGGTTCTAAACAAGATGCCAAACCTACTCCGACCCCTACACCAAGTCCAGCTCCTGGTAAATACTCTACTGCAGGCAAGAATTTAGAAGCTATGGCAGGTGACGTACAAGCTGGTAATGTTGGAGATGGCGATACACGTAAAAACAATCTTGGTAAGTACTATATAGGAGTTCAAGCAATCGTAAACCACCGTGTAACCGGTAAAGATGCGACTGATGTCCTAGTTGGTGAAACTAAGAAAGGTGTGTATGGCAATGGTGATGGACGTAAGAACCTATTGGGCAATTACTACAAGTCAGTTCAAGCTAAGATTGATGGAGCAGCACCTACAGCGGCCACCCGATCGTACACAGTTCAAAATGGCGACACTTTGTCTGGAATCGGATCCAAGCTAGGTATCTCTTATCTAACATTGGCTGCTAAGAACGGGATCAAAGCACCATACACAATATTCCCGGGACAAAAGATTAAGTATTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6wAjV) rather than this protein.
PDB ID
6wAjV
Method AlphaFoldv2
Resolution 93.99
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50