Protein

Protein accession
A0A6G5Y3X8 [UniProt]
Representative
8tQ4T
Source
UniProt (cluster: phalp2_40151)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRNRIKTKIMTVLVAVLAALGLAQPAQAAMQGYDTSNWQCGINTAQVPGDFVVVGSTWGTGQVSGRCLSGGVNTDANRQLFQAQGAGKKIGIYHYAMGGNPVAEADFFVDNNLGWIRKAKLVLDWESVDNPAFGNTAWPRQWASRVEQRTGVNPEIYVSDSAYWQVAGMEQSHNTGIWIAQYASMAPTGYQDRPWNSGARGEVMRQYSSSGRLPGWGGNLDIDIFYGDQNAWDKIANPSGQPVPSNPAPPSATPPSQPAPVSGSCSTVRYGDTLSGIAARLGVGWQQLSGYRSGNPNVIYAGETVCVRGAVQSAPSGGTYVVRSGDYLSKIWPGSWQQVAAANGLRPPYTIYPGQVLHVSGPTVSQSNSGRAYRVQRGDTLSAIAARLGVSTGYLAQTNGLRNPNLIYAGTWIRY
Physico‐chemical
properties
protein length:415 AA
molecular weight:44415,1 Da
isoelectric point:9,36
hydropathy:-0,31
Representative Protein Details
Accession
8tQ4T
Protein name
8tQ4T
Sequence length
200 AA
Molecular weight
22484,28850 Da
Isoelectric point
6,94546
Sequence
MIRMWRSVLACVCVLSLLFVPSASADMRGVDVSNWQCDIDTYALDADFVVAGATWGVGGFNNVCLTNGVNQAANYQLERAVDSGKSIGVYHYAMGHDANTEADFFIDNVRGYVGNAVLVLDWESQDNPSFGNGAWVETWVRHVHDRIQVWPIVYVQASALGQLTSYVREHWRRGGWRNMRQWLPPAIKQRRGCMARMAKP
Other Proteins in cluster: phalp2_40151
Total (incl. this protein): 5 Avg length: 356,0 Avg pI: 8,01
Protein ID Length (AA) pI
8tQ4T 200 6,94546
A0A6G5XZJ6 415 9,09522
A0A6G5Y067 328 4,80241
A0AA86RTB5 422 9,84395
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_38994
84ePK
 348 42,5% 141 2.940E-43
2 phalp2_36349
n1oN
 6 40,3% 124 9.948E-31
3 phalp2_20806
5TBA5
 9 38,3% 133 3.476E-30
4 phalp2_20117
23DDy
 70 30,3% 188 9.643E-28
5 phalp2_39219
3xEyz
 21 32,8% 140 1.694E-19
6 phalp2_3635
4SEzC
 3 28,6% 143 4.432E-17
7 phalp2_2231
4klcC
 109 30,8% 136 7.107E-16
8 phalp2_36157
6TiaL
 25 32,3% 136 2.067E-12
9 phalp2_7474
4TFQX
 5 29,4% 139 5.415E-06
10 phalp2_4437
2ScQK
 2 25,7% 140 1.880E-04

Domains

Domains [InterPro]
Disordered region
GH25
Representative sequence (used for alignment): 8tQ4T (200 AA)
Member sequence: A0A6G5Y3X8 (415 AA)
1 200 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Caudoviricetes sp
[NCBI] 		2832643 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN855759 [NCBI]
CDS location
range 2743 -> 3990
strand -
CDS
ATGCGCAATCGCATAAAGACCAAGATAATGACTGTCCTGGTGGCTGTGCTTGCAGCGTTGGGTTTGGCTCAGCCTGCGCAAGCGGCCATGCAGGGCTACGATACCAGCAACTGGCAGTGCGGCATCAACACGGCGCAAGTGCCTGGCGATTTCGTGGTGGTTGGATCCACCTGGGGTACGGGTCAGGTTTCTGGCCGGTGCCTGTCTGGCGGGGTCAACACTGATGCCAACCGTCAGCTTTTCCAGGCTCAAGGTGCTGGCAAGAAGATAGGAATTTATCACTATGCCATGGGCGGCAACCCTGTAGCAGAGGCAGACTTTTTCGTAGACAACAATCTGGGCTGGATACGCAAGGCCAAGCTCGTGCTGGACTGGGAATCAGTCGATAATCCCGCGTTCGGCAACACTGCATGGCCCCGACAGTGGGCTAGCAGGGTAGAGCAGCGTACCGGTGTCAATCCAGAGATCTATGTTTCCGACTCCGCATACTGGCAGGTCGCCGGGATGGAACAGTCGCATAACACCGGCATATGGATAGCCCAGTACGCTTCCATGGCACCGACCGGATACCAGGATAGGCCCTGGAATTCCGGTGCGCGTGGCGAGGTGATGCGCCAATACTCCAGCAGCGGCAGGCTCCCAGGCTGGGGCGGCAATCTGGACATTGATATTTTCTACGGCGACCAAAACGCATGGGATAAGATAGCCAATCCCAGCGGTCAGCCTGTCCCGTCCAACCCGGCGCCACCGTCTGCAACGCCACCGTCGCAACCTGCACCAGTCTCAGGGTCTTGCAGCACAGTACGATACGGGGATACGCTCAGCGGCATAGCCGCGCGTCTTGGTGTGGGCTGGCAGCAGCTATCCGGCTACCGGTCAGGCAATCCGAACGTGATCTACGCTGGCGAGACGGTCTGCGTCAGGGGTGCTGTCCAGTCTGCCCCATCCGGTGGCACGTATGTGGTGCGATCCGGTGACTATCTCAGCAAGATATGGCCCGGATCATGGCAGCAGGTAGCTGCGGCTAACGGGTTGCGGCCACCGTACACGATCTACCCTGGGCAAGTGCTGCATGTGTCAGGGCCTACCGTCTCCCAGAGCAATAGTGGTAGGGCCTACCGGGTACAGAGGGGTGATACGCTGAGTGCCATCGCGGCACGGCTTGGTGTCAGCACCGGCTATCTCGCTCAGACCAATGGCCTGCGCAACCCCAACTTGATCTATGCTGGTACATGGATCAGATACTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8tQ4T) rather than this protein.
PDB ID
8tQ4T
Method AlphaFoldv2
Resolution 81.54
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50