Protein

Protein accession
A0A6G5XZE5 [UniProt]
Representative
3WE0c
Source
UniProt (cluster: phalp2_24350)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MTVLNAHDNASYQAGIDNSIVESDIVITKISEGTSYLNPARDTQISSALRGNKLIGLYHFALGGDYKAEANFFLRNAKPYLKNAVLVLDYENGVVPVGKADYAEKWLDYVYQCTGVKPMLYIGLADENLYKWDGVAKKYCLWYAQYDTMAPWYGFTPNKKLTYGRVIHWSQKKIAMYQYTPSGYIKGYNGPLDLSAYYGTKVDWANHSNNDIKGDYREMEWHPKVNALDMGVFMVTKKGKTTTVWDSPDIATRKDTGLRLENGKNYIIFGDKNGFLKLGKNQWVDSATGVVKKNKLHYYAKANCTCIVERETRGYSSTKEKATGRVFKKGEKYKTFGYFDGFLQVGAGKDKFIPAKDVKIIL
Physico‐chemical
properties
protein length:362 AA
molecular weight:41010,3 Da
isoelectric point:9,24
hydropathy:-0,48
Representative Protein Details
Accession
3WE0c
Protein name
3WE0c
Sequence length
600 AA
Molecular weight
65510,49950 Da
Isoelectric point
6,43852
Sequence
MIKFYVPGFGTPKKPDDRHGDAQVLSDGAYTLVIDGGDATMSDKLITWLRAQGMKEVCLVVSHWHYDHYHGIERIIKDKAFTVSKLYCPKPSNLVPGLSSKWAGDIQSEINAAGRIISEAKDRGTEVVYLTRGDEVTLGDIRFKVYLAQPNKCANDDAHAWAFVNYGSLCLYFPDLCYLTTGDGPEAIKDAVAYFGGPVKWFKIPHHGNACTQSNTAACKAAGAVLAWYNGLEPQGPGTTAFTQYGARRCKQAGLMVWDTIGEISGRADAGRLTLTHNGTTYVENIPYKKGEVKVPTLYGIDIASYQAGIDLGKVPGDFVIVKATQGTGYVNPYFTAQIESAIKGGKLIGLYHYAGGNDARAEAEYFVSKITKYLKSAVLVLDWESIQNRAFNKSMVSWCKKWLDRVYELTGVRPLIYMSQSVTNSYDWSSVANDYGLWVAAYGSNTATGYKETYAYGKTGAWKYPAIFQYTSNGQLAGWNGRLDLNIAYMDKTAWGKYADPGVVQEAETETMNEPKPAAVETRTVTVTLPVCKLGSEGMPVRLIEAALGAEMEGVETTTTGVFNDELDAKVKAFQAAHSLTVDGIVGGATWPALLGSWK
Other Proteins in cluster: phalp2_24350
Total (incl. this protein): 3 Avg length: 441,3 Avg pI: 8,43
Protein ID Length (AA) pI
3WE0c 600 6,43852
A0A6G5YJX9 362 9,60593
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_25237
40EaA
 18 31,3% 706 4.192E-83
2 phalp2_1517
23Keb
 4 26,0% 533 1.382E-31

Domains

Domains [InterPro]
Unannotated
GH25
PG_1
Representative sequence (used for alignment): 3WE0c (600 AA)
Member sequence: A0A6G5XZE5 (362 AA)
1 600 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacteriophage sp
[NCBI] 		38018 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN855673 [NCBI]
CDS location
range 340 -> 1428
strand -
CDS
ATGACTGTACTCAACGCACACGATAATGCAAGCTATCAAGCGGGCATTGACAATAGCATTGTGGAGAGCGATATTGTTATTACCAAAATAAGTGAGGGGACATCTTACCTCAACCCTGCTCGCGATACACAAATATCAAGTGCTTTACGTGGAAATAAACTAATAGGGCTATATCATTTTGCCCTTGGAGGCGATTATAAAGCCGAAGCTAATTTCTTTTTAAGGAATGCAAAGCCCTATCTAAAAAATGCTGTGCTTGTTTTAGATTATGAAAATGGTGTTGTTCCAGTCGGCAAAGCTGATTACGCTGAAAAATGGCTAGACTATGTTTACCAATGTACAGGTGTTAAGCCTATGCTGTATATTGGACTTGCTGATGAAAACCTGTACAAATGGGATGGAGTAGCGAAGAAATACTGCTTGTGGTATGCACAATATGACACTATGGCACCATGGTATGGTTTTACGCCAAACAAAAAGCTAACGTATGGCAGAGTTATCCATTGGTCGCAAAAAAAAATAGCAATGTACCAGTACACACCTAGCGGGTACATTAAGGGATATAATGGACCACTTGACCTTAGCGCATACTATGGTACTAAAGTCGACTGGGCAAATCACTCTAACAACGACATTAAAGGAGATTATAGAGAAATGGAATGGCACCCAAAAGTTAACGCGTTAGATATGGGCGTGTTTATGGTTACAAAAAAAGGAAAAACAACTACAGTGTGGGATAGCCCTGACATTGCTACACGTAAGGACACCGGTTTAAGATTAGAAAATGGGAAGAACTATATTATCTTTGGCGACAAAAATGGCTTCTTGAAGCTTGGCAAAAATCAGTGGGTAGATAGTGCTACTGGGGTTGTAAAAAAGAACAAACTCCATTATTATGCAAAAGCAAATTGTACGTGCATTGTTGAGCGAGAAACTCGTGGATATTCTTCCACAAAAGAAAAAGCTACTGGAAGAGTATTTAAAAAAGGCGAAAAGTACAAGACTTTTGGCTACTTTGACGGCTTTCTACAAGTTGGAGCGGGGAAAGACAAATTTATCCCTGCAAAAGATGTGAAAATTATATTGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3WE0c) rather than this protein.
PDB ID
3WE0c
Method AlphaFoldv2
Resolution 83.63
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50