Protein

Protein accession
A0A3Q9R9W2 [UniProt]
Representative
41TB1
Source
UniProt (cluster: phalp2_37267)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MQLSSKGLEAIKFFEGYHSEVKNDNSVIPTIGYGTIRINGRPVTMGMKITAEQAEQYLLADVENYVGAQTK
Physico‐chemical
properties
protein length:71 AA
molecular weight:7852,8 Da
isoelectric point:5,68
hydropathy:-0,31
Representative Protein Details
Accession
41TB1
Protein name
41TB1
Sequence length
248 AA
Molecular weight
26793,24530 Da
Isoelectric point
5,02385
Sequence
MLYIGVVEDRNDPLKLGRCKVRVIGLHTHDAAKLPTADLPWAVPMQPTTSAAISGIGTTPLGLVEGTSVIVMFRDDEKQFPIILGSIAGIPQSTSSDISSDDSTIRIKIDGELKQVNEQTNVLLDGSGNPVVDSSGAPVTTSQESVTLENANKLKRAVEYTPSANCVALIKRFEGLRLQAYQDSVGIWTIGYGTTRINGSPVQPGMIITEVQAEKYLSEDLKEFVPLVQRNTRALITQSMFDALCSFT
Other Proteins in cluster: phalp2_37267
Total (incl. this protein): 18 Avg length: 245,8 Avg pI: 5,29
Protein ID Length (AA) pI
41TB1 248 5,02385
1AWqj 319 4,83867
1Idqp 275 5,07796
1MSDF 350 4,63638
1qpxx 282 6,11993
23078 302 4,53828
25vx7 261 5,76918
2fD7H 243 4,24294
460Cf 243 5,44332
4vQS7 212 4,99458
57boI 226 6,90738
5bcJI 318 5,43571
5gZiw 224 5,82153
6BKnc 224 4,92120
8ovNW 237 5,44440
ILVk 204 5,68841
SNDG 185 4,66127
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_30923
SAFq
 18 47,1% 267 9.088E-81
2 phalp2_39833
SgIH
 7 36,5% 241 1.394E-48

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Shigella phage vB_SflM_004
[NCBI] 		2500763 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK295205 [NCBI]
CDS location
range 71400 -> 71615
strand +
CDS
ATGCAACTCTCAAGTAAAGGCTTAGAAGCCATTAAGTTCTTTGAAGGGTATCACTCAGAGGTTAAAAATGACAATTCTGTAATCCCTACAATTGGTTATGGTACAATTCGTATCAACGGAAGACCTGTTACGATGGGGATGAAGATTACTGCCGAGCAAGCTGAACAATATCTCCTTGCAGATGTTGAGAACTATGTAGGTGCACAAACAAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (41TB1) rather than this protein.
PDB ID
41TB1
Method AlphaFoldv2
Resolution 83.28
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50