Protein

Protein accession
A0A345BNP2 [UniProt]
Representative
7YA8O
Source
UniProt (cluster: phalp2_15490)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTEIIKYFADESNYKKSKGRTIKYIVYHYTGNINDSALSNCRYFKNKNIGSSAHFFVDDKSIYCSVDPENIAWSVGLGNRKEPYKNMPMFGVITNSNSISIEMCGGKTSYEAPEETIKNAIELGSFLMGVYGLTTNDVFRHYDVTGKQCPAWLIADDKWNKFKERFEEMNYEKFMYYMNMFFNDKSKMSASEWARKYFEYIKELGIMNGTEPKSFVTREELAVVIWRLINKINED
Physico‐chemical
properties
protein length:235 AA
molecular weight:27444,9 Da
isoelectric point:6,84
hydropathy:-0,53
Representative Protein Details
Accession
7YA8O
Protein name
7YA8O
Sequence length
251 AA
Molecular weight
28763,63970 Da
Isoelectric point
8,10801
Sequence
MIALSDIPLILAHKQNFSSVRRSTLTIKYIVLHYTSNINDTALNNVKYFNSTVVKASAHYFVDDETIYQSVPCDYPAYSVGLGSMSKPYIPDPPFYTKCTNSNSISIEMCGGKTSRECSTKTKQRACELTVALMKRYNIPPTRVIRHYDVTGKKCPAWAVEDPAKWLEMQIEINSLYHEEDDTMLETDANYEVFKRFMDRYLAEIAKEPATWDKNAMIYTEERGIITGNRPKSFVTRGELATVVERVMKFK
Other Proteins in cluster: phalp2_15490
Total (incl. this protein): 2 Avg length: 243,0 Avg pI: 7,48
Protein ID Length (AA) pI
7YA8O 251 8,10801
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_29669
8sfID
 1005 47,9% 167 4.736E-44
2 phalp2_29527
23SbO
 38 50,6% 162 6.235E-41
3 phalp2_1605
81mMl
 270 41,7% 175 1.159E-30
4 phalp2_29517
21wOt
 7 38,5% 187 4.155E-28
5 phalp2_3793
5X3JD
 59 41,0% 178 5.660E-28
6 phalp2_424
7xFGZ
 10 29,5% 257 2.653E-27
7 phalp2_40668
5i2H9
 1 34,5% 200 1.076E-25
8 phalp2_20567
4ya0O
 12 35,6% 174 2.713E-25
9 phalp2_25288
86peP
 187 35,5% 163 2.341E-24
10 phalp2_3939
7bfSL
 153 33,3% 165 9.256E-21

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 7YA8O (251 AA)
Member sequence: A0A345BNP2 (235 AA)
1 251 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctbd591
[NCBI] 		2675445 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MH552495 [NCBI]
CDS location
range 15828 -> 16535
strand -
CDS
ATGACCGAAATAATTAAATATTTCGCTGATGAATCTAATTACAAAAAATCAAAAGGCAGAACAATTAAGTATATTGTGTATCACTATACTGGAAACATAAATGATTCAGCCTTATCTAACTGTAGGTACTTTAAAAATAAAAATATTGGTTCTAGCGCACACTTTTTTGTCGATGACAAGTCTATTTATTGTAGCGTGGACCCTGAAAATATCGCATGGTCTGTTGGATTGGGAAATAGAAAAGAACCCTATAAGAATATGCCGATGTTTGGTGTTATAACTAATTCAAATAGTATCAGTATAGAAATGTGTGGTGGTAAAACCAGTTATGAAGCACCAGAAGAAACTATAAAAAATGCTATCGAGTTAGGTTCATTTTTAATGGGTGTGTATGGCCTAACAACAAATGACGTGTTTAGACATTACGATGTGACAGGAAAACAGTGTCCAGCATGGTTAATTGCCGATGACAAATGGAATAAATTTAAAGAGAGGTTCGAAGAAATGAATTACGAAAAATTTATGTATTATATGAATATGTTTTTTAATGATAAAAGCAAAATGTCTGCTAGCGAATGGGCTAGAAAATATTTTGAATATATAAAAGAATTAGGTATAATGAATGGCACGGAGCCGAAATCGTTTGTAACAAGAGAAGAATTAGCCGTAGTTATCTGGCGATTGATTAATAAAATTAATGAGGATTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0009254 peptidoglycan turnover biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00001561

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7YA8O) rather than this protein.
PDB ID
7YA8O
Method AlphaFoldv2
Resolution 92.03
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50