Protein

Protein accession
A0AAV2C6J5 [UniProt]
Representative
1uHlG
Source
UniProt (cluster: phalp2_33847)
Protein name
Baseplate central spike protein
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MFNNSVKWFTGIVENREDPLMLGRVQVRIHGIHPSLSAHGDIQGLPTEDLLWITPVQDITSAAISGIGQSPTGIVEGSMVFGLALDERYLNCVILGTIAGQYTEKPLTTEGFCDPSGAYPRYIGNDVNILARGGINPETGQTTKPDSVYIRDENTGVAVNPDDEPLDQIPVDDNPDFTIEKMLRGDEGYREKWYLDSEGYPTIGIGHLIIYKKTSDLGIINNELSKLVGREVTNGRLTAEEVSKVFADDIEKTRRDMRKHPRIAPVYNKCNASRRMALENMAFQMGVGGLGKFKNSLAAMLAEEWKQAYDGLRQSVWANQTPGRSSRVSKIILTGNLESYGVIAPKKEESISDDPRARLRNARIAAYKTQRAEEDPEAPFTPQDTRIMFKEPKSSYSARYPYNHVYESESGHIIEIDDTPSHERYHRKHPSGTFEETRPDGTRVEKIEGDDYLIVKQGRKVNVKGNLQVVVEGDAQVYYMGNVMQTVDGNVTEFIRGNVNQTVEGTANMHVVGDVTAQLDANLTANVKGNAELMIEGNTTETIKGNYDLTVEGNFNMTVNGTKSDQVNGDWSRNCGASVKDIASGTVKIDGSRIDLG
Physico‐chemical
properties
protein length:597 AA
molecular weight:66004,1 Da
isoelectric point:5,19
hydropathy:-0,54
Representative Protein Details
Accession
1uHlG
Protein name
1uHlG
Sequence length
353 AA
Molecular weight
38473,35910 Da
Isoelectric point
5,37040
Sequence
MSYRIDAGTVTFQEAPREGAEVEIIVSKVNTLKGFSDPRGFYPRRVNEADTNRLAVNDQRNQHPVNIFKSNNVDDLTGEPKSSYNAQYPFNHVKETESGHIVEFDDTPGHERIHEFHRSGTFYEVHPDGTKVTKIVGDDFEIVHNNKQVRVRGNMKVFVDGDADLYVRGSMNAQVDEHLKFNVGQNIDFHAGKNIRMFANESIEMTAQTTMTQQSVGKFLQQSQGDMQIITAANFTNAVLGNYDMVVDGDSLTDIKGNLSTNITGNVGMLAEGTFATTIKGATSFHTESTMELASTLAMKIDTGNKLDIGSGNAMNLAGSTIDLNSAPRSAATITAVVPIVPRAKPSPPAGDG
Other Proteins in cluster: phalp2_33847
Total (incl. this protein): 27 Avg length: 573,0 Avg pI: 5,18
Protein ID Length (AA) pI
1uHlG 353 5,37040
1sJrw 277 5,25041
6OtC3 436 4,68418
A0A0B7MRI8 599 5,19062
C4MYV6 599 5,14691
A0A5B9MWH8 599 5,19062
A0A220NTH3 599 5,19062
A0A345BRV0 599 5,19062
A0A482GDE3 599 5,19448
A0A482GFR9 599 5,15396
A0A482GG25 599 5,14691
A0A482GPG5 599 5,14691
A0A650DG43 599 5,19062
A0A6B9LNU3 599 5,19062
A0A6B9SQR1 597 5,19062
A0A6B9SVJ2 599 5,19062
A0A6B9WS51 599 5,19062
A0A7S5VJK0 640 5,37472
A0A7S6HTR7 599 5,15003
A0AAE7SAV4 599 5,19062
A0AAE9P4Y5 599 5,23308
A0AAF1KAY0 599 5,14691
A0AAX4QXG8 597 5,19062
A0AAX4R193 597 5,19062
A0AAX4R1A7 597 5,19062
A0AAX4R4R9 597 5,19062
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_21289
1xsTC
 5 83,9% 230 6.232E-114
2 phalp2_1719
2n3Y4
 45 38,7% 232 3.923E-57
3 phalp2_10203
IyZJ
 2 36,3% 256 6.604E-35

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage vB_Eco_SAP
[NCBI] 		3044329 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OZ034687 [NCBI]
CDS location
range 153067 -> 154860
strand +
CDS
ATGTTTAATAACTCCGTTAAATGGTTTACCGGAATTGTAGAAAACAGGGAAGACCCATTAATGCTGGGGCGCGTTCAGGTTAGGATTCATGGTATACATCCTTCGCTATCCGCACACGGTGACATTCAAGGTCTTCCAACCGAAGATCTATTATGGATTACGCCAGTACAAGATATTACAAGCGCGGCGATCTCCGGTATAGGTCAAAGCCCTACTGGTATTGTTGAAGGTTCAATGGTATTTGGTTTGGCTTTAGATGAACGTTATTTAAACTGCGTTATTCTTGGTACTATTGCCGGACAATATACAGAGAAACCACTCACTACAGAAGGTTTTTGTGACCCTTCTGGTGCATATCCTCGTTATATTGGTAATGATGTTAATATTCTTGCTCGTGGCGGTATTAACCCAGAAACCGGACAAACAACAAAACCTGATAGTGTCTATATTCGAGATGAAAACACTGGAGTTGCAGTAAATCCAGACGACGAGCCATTAGACCAAATTCCGGTTGATGATAATCCTGATTTTACAATAGAAAAAATGCTGCGGGGCGATGAGGGATATCGCGAGAAATGGTATCTTGATTCAGAAGGATATCCGACAATAGGCATCGGGCATTTGATCATTTATAAGAAAACCAGTGATCTTGGTATTATCAATAATGAACTTTCTAAGCTGGTAGGGCGTGAAGTTACAAACGGAAGACTTACCGCCGAAGAAGTTAGTAAAGTATTTGCTGACGATATAGAAAAGACTCGTCGTGATATGCGCAAACATCCACGAATTGCACCTGTCTATAATAAATGTAATGCCTCACGTCGTATGGCATTAGAAAATATGGCGTTTCAAATGGGTGTTGGAGGATTGGGTAAATTTAAGAATAGTCTTGCTGCGATGTTAGCGGAAGAATGGAAACAAGCCTATGATGGATTACGTCAATCGGTATGGGCTAACCAAACTCCAGGACGCTCCAGCCGTGTTTCTAAAATTATTTTAACTGGTAACTTAGAATCATATGGCGTAATTGCTCCAAAGAAAGAGGAATCAATTTCGGATGATCCGCGAGCACGTTTGAGAAATGCCCGTATTGCTGCCTATAAGACGCAGAGAGCAGAAGAAGACCCAGAAGCACCGTTTACCCCACAAGACACACGAATCATGTTTAAAGAGCCTAAGAGTTCGTATTCTGCAAGGTATCCATATAACCATGTGTACGAGTCAGAGAGCGGTCATATTATCGAGATTGATGATACTCCTTCTCATGAGCGATATCATCGTAAACATCCTTCTGGTACATTTGAAGAAACCAGACCGGACGGAACGAGGGTAGAAAAGATTGAAGGCGATGATTATCTGATCGTTAAACAAGGCCGGAAAGTAAACGTCAAGGGTAATTTGCAAGTTGTTGTTGAAGGTGACGCGCAAGTTTATTATATGGGTAATGTGATGCAAACCGTTGATGGTAACGTCACTGAATTTATTCGTGGCAATGTTAATCAGACCGTTGAAGGTACTGCTAACATGCATGTTGTAGGTGATGTTACCGCTCAGCTTGACGCTAATTTAACGGCTAATGTCAAGGGTAATGCTGAATTAATGATCGAGGGTAACACTACCGAAACAATTAAAGGTAACTATGATTTAACCGTTGAGGGTAATTTTAATATGACCGTCAATGGCACTAAATCAGACCAGGTTAATGGTGACTGGTCCCGTAATTGTGGTGCAAGCGTTAAAGATATTGCATCTGGTACAGTTAAAATTGATGGTAGCCGTATTGATCTTGGATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0098003 viral tail assembly biological process None (UniProt)
GO:0098025 virus tail, baseplate cellular component None (UniProt)
GO:0098932 symbiont entry into host cell via disruption of host cell wall peptidoglycan biological process None (UniProt)
GO:0098994 symbiont entry into host cell via disruption of host cell envelope biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		HAMAP-Rule:MF_04151

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1uHlG) rather than this protein.
PDB ID
1uHlG
Method AlphaFoldv2
Resolution 88.58
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50