Protein

Protein accession
A0AAF0LUT0 [UniProt]
Representative
82zJS
Source
UniProt (cluster: phalp2_15486)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MATIKEILKPNNTANDIVLHVGANKTTTPENAYSDLQFQAGFYWPIVKVRSTTFTKPAIKTFELNFGYQLLPTLEFMVVDDSRSFQQSDYPVKNDVVTVYLGNQYDTSSKPIQLDFLIDDVTTLNSMDGSGAVKHSFTCTLAIEHAFENINFAKDETSMGVLYELCKAMNLGLVTNLESTNDRYKYRQYSKTNIEYLKDVCSKVYVDDATIIHYYIDQYFRLNVIDINAILSAPAPRLPVRRDITFFKTLATPEELVLNNAQYNLNNVQFKFGSYTTSSNAFETYKEVKPVESTVINKDYSQAIVKSSVKDTRVKANATTGGATKSENVTENNVTNSKRIQTIAINGEHNSNVQQLGANANKSRFRYLTNNSITLRLNNPSNLLNINQMVPVELYKPDQFVQTPLKNSDTNLDSTQKPITPDGTEAMNPTLSGDYAITGMTFAYRQNQNLWQELKLIRREWKPQHYDVDKSRKIDLSEATFGAPKPYTYPPPPPPPPVDNSGYGGQYGGSLGNWMQIARGELGTSEVAGAGSNPRIDEYHRVGGGLSGNQANDATAWCGSFVGWCMVKAGYPKPNGSAAAISWANYGIPCAPGTIGAIIVLKLKPSSMTYSGNHVGFCAGLNGDKVSILGGNQGNSVSQLNMASAKVIAWRLPPGSPSQGIANAGNSVAPTGPLRISNQGVEFIKSKEGCKLTAYWDSYGKVWTIGYGNTKQARPGMTITYQQAEQLLRQDIVYFENYINQNVKVKLTQAMFDALVCLTFNTGPGKVSPSSAIGIALRNRQYQTAADTFLRYNTSKGKFLQGLDTRRKQERQMFMSQGVNPI
Physico‐chemical
properties
protein length:822 AA
molecular weight:90828,4 Da
isoelectric point:8,92
hydropathy:-0,41
Representative Protein Details
Accession
82zJS
Protein name
82zJS
Sequence length
261 AA
Molecular weight
29336,00690 Da
Isoelectric point
5,40479
Sequence
MYKIFSTLLLIVNLGGVTEGIAPPFSMANENKHISDRGISVITYYEGCYLEAYWDPYGKVWTIGYGHTNGVYEGMVITKEQAIEFLKEDCLIAEKGIKDYITRELKQYEFDALVSFLFNVGEYTLYNDKKLRTYVNEGNSQAVYDRLQEYVYGGGQVLPGLVKRRRTEGELYRDNDLSSIGGGSGEVDPTPPDPPDPPKPPTEGNYRLKSRLVYGSSALFPILIQSTDYVFNLVSIIGDVAIIKDSTGKVYKTNKKNLIKI
Other Proteins in cluster: phalp2_15486
Total (incl. this protein): 6 Avg length: 447,7 Avg pI: 6,62
Protein ID Length (AA) pI
82zJS 261 5,40479
82rGY 258 5,19482
82tQY 264 5,21977
82yrr 259 6,12823
A0AA96HAT1 822 8,86790
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_29738
1pBjt
 830 38,9% 177 5.230E-32
2 phalp2_2498
5GMvl
 297 38,7% 160 3.352E-31
3 phalp2_2176
3Yhf4
 930 36,9% 176 1.371E-29
4 phalp2_15045
7iQxx
 18 37,9% 166 3.463E-29
5 phalp2_3619
4ONI2
 18 36,9% 165 1.046E-25
6 phalp2_6008
4MOEK
 54 35,5% 169 2.622E-23
7 phalp2_34268
3g7XB
 9 33,1% 172 5.590E-22
8 phalp2_29434
1lLit
 2 30,5% 213 1.397E-21
9 phalp2_14179
2AnJ3
 6 33,8% 183 1.896E-21
10 phalp2_34935
4zXUV
 2 27,6% 159 8.716E-21

Domains

Domains [InterPro]
Disordered region
GH24
Unannotated
Representative sequence (used for alignment): 82zJS (261 AA)
Member sequence: A0AAF0LUT0 (822 AA)
1 261 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Chryseobacterium phage MA9V-1
[NCBI] 		2936916 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OR050627 [NCBI]
CDS location
range 119283 -> 121751
strand +
CDS
ATGGCAACAATTAAAGAAATTTTAAAGCCTAACAACACAGCTAACGATATCGTTTTGCATGTTGGCGCTAACAAAACTACTACGCCAGAGAATGCATACTCAGACTTACAATTTCAGGCTGGATTCTATTGGCCTATTGTAAAAGTTAGGTCGACTACATTTACTAAGCCAGCAATCAAAACTTTTGAGCTAAACTTTGGCTACCAACTATTACCTACATTAGAGTTTATGGTAGTTGATGACTCTAGGTCATTCCAACAATCTGACTATCCTGTTAAAAATGATGTAGTTACTGTGTATTTGGGCAATCAATATGACACCTCGTCAAAGCCGATACAGCTAGACTTCCTAATTGATGACGTAACTACACTAAATAGCATGGACGGTTCTGGTGCAGTTAAGCATAGCTTTACTTGTACGTTAGCAATCGAACATGCATTTGAAAACATAAATTTTGCTAAGGACGAAACATCAATGGGCGTTTTGTATGAACTTTGTAAAGCTATGAACTTGGGGTTAGTTACAAACCTAGAAAGTACTAATGACCGTTACAAATATCGTCAATATAGCAAAACAAACATTGAATATTTGAAAGATGTTTGTTCCAAAGTTTATGTTGATGATGCTACAATTATTCATTATTACATAGATCAGTACTTTAGACTTAACGTTATTGACATCAACGCAATACTTAGTGCACCAGCGCCTAGATTGCCAGTACGTCGTGACATTACGTTCTTCAAAACGTTAGCAACTCCTGAGGAGCTAGTGCTAAACAATGCTCAGTACAACTTAAATAATGTGCAATTTAAGTTTGGTAGCTACACTACGTCTAGCAATGCGTTTGAAACGTACAAAGAAGTTAAGCCTGTTGAGTCTACAGTAATTAACAAAGATTATTCACAAGCTATTGTTAAAAGCTCAGTAAAAGATACGCGAGTTAAGGCTAACGCTACAACCGGCGGCGCTACAAAAAGTGAGAACGTTACAGAAAATAACGTAACAAATAGCAAACGTATACAAACAATTGCAATTAATGGCGAACACAATAGTAACGTTCAGCAACTAGGAGCTAATGCAAACAAAAGTAGATTCCGCTACCTAACTAACAACTCCATAACGTTACGACTTAACAATCCTAGCAACTTACTCAACATTAATCAAATGGTACCTGTTGAGTTGTATAAACCAGATCAATTTGTACAAACGCCGCTAAAAAATTCAGATACAAACCTAGATAGCACACAAAAACCAATAACGCCAGATGGTACTGAGGCTATGAATCCTACGCTATCAGGTGACTATGCCATAACAGGAATGACTTTTGCATATCGTCAAAATCAAAACTTATGGCAGGAATTGAAATTGATTCGTAGAGAATGGAAACCTCAACATTACGATGTAGACAAATCTCGTAAAATTGACTTATCTGAAGCTACGTTCGGAGCGCCAAAGCCTTATACTTACCCACCGCCACCACCACCGCCACCAGTAGATAACTCAGGCTATGGCGGTCAATATGGTGGGTCATTGGGCAACTGGATGCAAATTGCTAGAGGTGAGCTAGGAACTTCAGAAGTTGCTGGTGCAGGTTCAAATCCAAGAATTGACGAATATCACAGAGTTGGCGGAGGACTTTCAGGAAACCAAGCTAACGATGCTACTGCATGGTGCGGATCATTCGTAGGCTGGTGTATGGTCAAGGCGGGCTACCCTAAGCCTAATGGCTCGGCTGCAGCAATTTCATGGGCTAACTATGGTATACCCTGTGCTCCTGGCACAATTGGCGCAATCATCGTATTGAAACTTAAGCCTAGTAGCATGACTTATTCAGGAAACCACGTAGGATTTTGTGCAGGTTTAAATGGCGATAAAGTTTCAATTTTAGGAGGTAACCAAGGCAATAGCGTTAGCCAACTTAACATGGCTTCTGCAAAAGTTATTGCATGGAGGCTACCACCAGGTTCGCCTAGTCAAGGCATAGCTAATGCAGGCAATAGTGTAGCACCTACTGGACCTTTACGAATTTCTAACCAAGGTGTTGAATTTATCAAATCTAAGGAAGGTTGTAAACTTACCGCATACTGGGATAGCTACGGTAAAGTTTGGACTATAGGCTACGGAAACACTAAACAGGCTCGGCCAGGCATGACAATTACATACCAACAAGCCGAACAACTATTACGTCAAGACATTGTTTACTTTGAGAACTACATAAATCAGAATGTAAAAGTTAAGCTAACACAGGCTATGTTTGACGCTCTAGTATGTTTAACTTTCAACACTGGACCTGGTAAAGTATCGCCAAGCTCAGCAATTGGAATTGCTTTGCGTAATAGACAATACCAAACTGCAGCAGATACATTCTTACGCTACAATACGTCAAAGGGTAAATTTTTACAGGGCTTAGATACTAGGCGTAAACAAGAACGTCAAATGTTTATGTCGCAAGGCGTAAATCCAATATAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (82zJS) rather than this protein.
PDB ID
82zJS
Method AlphaFoldv2
Resolution 78.17
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50