Protein

Protein accession
A0AAE9X6T6 [UniProt]
Representative
2soYi
Source
UniProt (cluster: phalp2_20321)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKRLVAPIAAMVVVGAAGTGLIKQSEGLRFNVYLDGAKIPTVCYGHTGPDVQMGQPARTQEECDKLLKEDLLRHSVAVTKCVNTPLTQYQYDALVSFAYNVGPTKFCRSTLAKKVNQRDFKGAAAEFPRWNKIVVDGKVTVSAGLSARREREKQLFEGKVPK
Physico‐chemical
properties
protein length:162 AA
molecular weight:17799,5 Da
isoelectric point:9,61
hydropathy:-0,25
Representative Protein Details
Accession
2soYi
Protein name
2soYi
Sequence length
120 AA
Molecular weight
13549,13600 Da
Isoelectric point
7,98217
Sequence
CESARRVTREAGRLFIYQEVADKLLEQDVKQVALFVHSVSRVPLSQHQFDALCSFVFNVGQNNFVESTLRKKLNAGDYEGASSEFPRWKYGTVNGEKAVLPGLVARRDTEQALFNLKEPS
Other Proteins in cluster: phalp2_20321
Total (incl. this protein): 3 Avg length: 126,3 Avg pI: 9,08
Protein ID Length (AA) pI
2soYi 120 7,98217
7sWGq 97 9,64255
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37101
1bvx6
 877 52,4% 101 6.835E-31
2 phalp2_2632
6RhYr
 14867 51,5% 99 1.764E-30
3 phalp2_20456
3zJV8
 14 54,8% 82 1.844E-27
4 phalp2_9410
8Hj1q
 5109 50,0% 94 8.953E-27
5 phalp2_33221
5jbqV
 447 50,0% 100 8.953E-27
6 phalp2_4451
31DIk
 4919 47,0% 100 1.121E-25
7 phalp2_7764
77796
 37 58,3% 72 2.200E-22
8 phalp2_8099
6AkO5
 4 45,0% 102 1.067E-21
9 phalp2_39267
4724r
 247 42,0% 100 8.877E-20
10 phalp2_10930
4Fwcs
 17 41,4% 94 3.138E-19

Domains

Domains [InterPro]
GH24
Representative sequence (used for alignment): 2soYi (120 AA)
Member sequence: A0AAE9X6T6 (162 AA)
1 120 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Caulobacter phage KSC
[NCBI] 		3020398 Autographiviridae > Percyvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OQ135104 [NCBI]
CDS location
range 42388 -> 42876
strand +
CDS
ATGAAAAGACTAGTTGCCCCGATTGCCGCTATGGTGGTCGTCGGGGCGGCTGGTACTGGCCTCATCAAACAGTCCGAAGGGCTTCGCTTCAATGTCTACCTTGACGGCGCGAAGATACCCACGGTGTGCTACGGGCACACCGGTCCGGACGTTCAGATGGGCCAACCGGCCAGAACTCAAGAGGAGTGCGATAAGCTCCTCAAAGAAGACCTCCTGCGGCATAGTGTCGCAGTGACAAAGTGCGTTAACACTCCCTTAACACAATACCAGTATGATGCTCTGGTCAGCTTTGCGTATAACGTAGGGCCGACGAAGTTCTGCCGCTCGACCCTCGCCAAGAAGGTCAACCAGCGGGACTTCAAGGGGGCGGCTGCTGAGTTTCCGCGCTGGAACAAGATCGTGGTGGACGGCAAGGTGACCGTTTCCGCCGGACTTTCCGCGCGCAGGGAGCGTGAGAAGCAGCTATTTGAGGGGAAGGTACCCAAATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2soYi) rather than this protein.
PDB ID
2soYi
Method AlphaFoldv2
Resolution 86.93
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50