Protein

Protein accession
A0AAE8BMP4 [UniProt]
Representative
xiY3
Source
UniProt (cluster: phalp2_10187)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAAVRNGFIGCSVAAVLGLVSQIYPNALETSPEGLKLLAGYEDCTLTAYKDHVGVPTIGVGSTGCVTMGDTITLEEAAERFVQDVKEAEQCVITYFNGAEMPQPVFDSVTSLVYNVGCYGTRWNRKQDRPTYINMYANSGDWYKVCYRLGDFTKAGGVVSKGLVNRRTEEQRHCLTYRTYPASIQSE
Physico‐chemical
properties
protein length:187 AA
molecular weight:20568,0 Da
isoelectric point:5,47
hydropathy:-0,19
Representative Protein Details
Accession
xiY3
Protein name
xiY3
Sequence length
247 AA
Molecular weight
28488,69140 Da
Isoelectric point
6,64643
Sequence
MKISENGLKLIRSFEGCRLEAYKCPAGVWTIGWGHTGNVKAGQRITQAEADKMLTDDMEPYERNVDKYGTKYMWNQNEFDALVSFAYNVGSIDQLTAKGTRSRAEISEKILAYNRGGGKVLAGLTRRRQAEQKLFLTPISEQKKKGWQQEDGDWKYYLGNGEPVRNDWYWYDDKWYWFDGAGRMVKNTWYKYKDKWYYLGTDGAMLTGQQTIDGKWYVLNEDGAMVTDPVTLTPDQDGALTWPGLKE
Other Proteins in cluster: phalp2_10187
Total (incl. this protein): 70 Avg length: 254,4 Avg pI: 8,35
Protein ID Length (AA) pI
xiY3 247 6,64643
15K1m 312 7,16657
1G0Te 297 9,09689
1Hr4E 264 9,58176
21fWk 286 9,40789
21zFe 247 9,63507
239Ar 313 6,73283
23hIQ 288 9,30081
24oJM 285 8,49134
2lTDU 255 8,29246
3TG8m 255 9,57847
3WIhm 248 9,61012
3dO0R 248 9,69741
3dY6l 278 6,84759
3k2Uk 252 9,14079
3kIDu 255 8,30039
3kWMg 252 8,34693
3kY9y 254 6,33319
3ldso 255 8,94365
3leKD 255 8,75276
3mvls 255 8,28459
3pKvu 255 9,01972
3ppeg 228 9,21468
3qnNJ 255 8,28459
3qq8E 255 8,92347
3qqmE 255 9,01959
3rUQh 255 8,29246
3s7ZL 255 6,75142
3sOL6 252 7,66709
3sZxk 255 8,29246
3sqi4 255 8,20936
3t5LA 255 7,63270
3wr8m 255 7,54506
5PHmE 244 8,80814
5PgX4 252 5,86296
5Q792 226 9,02185
5Unyp 255 8,60887
5WLDh 247 7,61338
5XEIF 228 9,01115
5XJhP 255 9,06176
5XgnJ 255 7,65004
60raK 255 7,60048
64sUE 254 9,04790
67iDB 244 8,46459
6d1X2 269 8,88537
6dQDY 255 8,70131
6eNXf 240 9,12938
6gHZg 253 8,70396
6itTA 244 8,14863
6n2LS 252 8,60210
6uRcU 255 8,12406
6vvhN 257 5,97994
7rg7A 233 9,53528
82qOh 252 9,25993
84OEk 244 8,47148
84pll 255 8,58282
88Bbq 255 8,57444
8ddee 263 5,98858
8fc8q 252 9,33755
8jH3i 238 8,97982
8k3cY 255 8,54375
8keBL 274 9,29965
8lgeI 252 9,03649
8nXEF 255 7,54341
8synf 254 5,80914
8tTH7 252 8,28098
8vRbX 255 8,27692
a49V 247 9,64810
ouga 212 9,79077
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_23833
1mogV
 302 56,3% 158 1.131E-61
2 phalp2_2764
1lyD
 3 41,9% 231 4.382E-56
3 phalp2_24016
7V0GL
 4 38,2% 191 6.573E-30
4 phalp2_12668
1Z1Pv
 3 32,0% 178 2.870E-22
5 phalp2_34935
4zXUV
 2 30,9% 168 9.664E-20
6 phalp2_38353
ATmM
 19 28,5% 196 9.912E-15

Domains

Domains [InterPro]
GH24
Unannotated
Representative sequence (used for alignment): xiY3 (247 AA)
Member sequence: A0AAE8BMP4 (187 AA)
1 247 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Vibrio phage vB_VpaP_G1
[NCBI] 		2862773 Autographiviridae > Youngvirus > Youngvirus G1
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MZ592920 [NCBI]
CDS location
range 7827 -> 8390
strand -
CDS
ATGGCTGCTGTCAGGAACGGTTTCATTGGCTGTTCAGTGGCAGCAGTCCTCGGTCTGGTATCCCAGATTTACCCGAATGCGTTAGAGACCTCACCAGAAGGTCTCAAACTCCTTGCGGGTTACGAGGACTGCACACTGACCGCTTACAAAGACCACGTAGGAGTCCCTACAATCGGCGTAGGGAGCACGGGCTGTGTTACTATGGGTGATACCATTACTTTAGAGGAAGCCGCTGAGAGGTTCGTACAGGACGTTAAAGAGGCTGAACAATGTGTAATCACGTACTTTAATGGTGCTGAGATGCCCCAGCCTGTATTCGATAGTGTTACCTCCTTGGTATATAATGTAGGTTGCTACGGTACTCGCTGGAACCGTAAACAGGATAGACCTACTTACATTAACATGTATGCTAACTCCGGTGACTGGTACAAGGTATGCTACCGACTCGGTGACTTCACTAAGGCAGGTGGTGTAGTATCCAAGGGGTTAGTTAATAGACGTACAGAGGAACAGAGACATTGCTTAACTTACAGAACCTACCCAGCCTCGATACAGTCCGAGTAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (xiY3) rather than this protein.
PDB ID
xiY3
Method AlphaFoldv2
Resolution 94.41
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50