Protein

Protein accession
A0A6J5PTM4 [UniProt]
Representative
1ADQo
Source
UniProt (cluster: phalp2_29467)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MIKRQSVAGIGVSAALLIAVLQFEGYTDKAVIPVPGDVPTIGAGRTEGVKLGDKTEPVREMVFLLNNLENKYARKIRECIHVPLHVYEFDAYVSLSYNIGTSAFCKSTLVKKLNAGDYAGACQQILVWDKFKGKPLRGLTVRRQEEYAKCLNSAD
Physico‐chemical
properties
protein length:155 AA
molecular weight:17079,6 Da
isoelectric point:9,03
hydropathy:-0,06
Representative Protein Details
Accession
1ADQo
Protein name
1ADQo
Sequence length
255 AA
Molecular weight
28128,11550 Da
Isoelectric point
8,96080
Sequence
MLNLPEVLKQGKVVTNPEAWKNGQINVAYLVGFLGLVLASLSFFGINLVVDDTTLNTIAGAIMALYGIYNQIATMASSDKVGFKSEPKTKPKVDKKEESKTGRVAIASLVIGSALTVGTITHFEGFRSKAYVDMAGIPTIGYGTTEGVKLGDTITKEEAERKLIKDVANKFHPAIAQCVKVPLYQHEYDAYASLVYNIGGANFCKSTLVKYLNESKYKEACEQILRWNRVKGEVVQGLNNRRQEEYRICLGEYNK
Other Proteins in cluster: phalp2_29467
Total (incl. this protein): 2 Avg length: 205,0 Avg pI: 9,00
Protein ID Length (AA) pI
1ADQo 255 8,96080
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_6864
3heUl
 25 36,8% 239 1.851E-28
2 phalp2_30186
3R0K4
 1 34,3% 172 1.920E-24
3 phalp2_23830
1lpLy
 242 37,3% 158 2.157E-19
4 phalp2_8169
6Xyoc
 32 32,3% 164 1.277E-13
5 phalp2_15693
38DRK
 2 33,7% 175 7.674E-13
6 phalp2_26895
4iseZ
 2 27,7% 180 1.326E-08
7 phalp2_4663
4DGWZ
 1 31,1% 228 3.356E-05

Domains

Domains [InterPro]
Unannotated
GH24
Representative sequence (used for alignment): 1ADQo (255 AA)
Member sequence: A0A6J5PTM4 (155 AA)
1 255 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796887 [NCBI]
CDS location
range 30209 -> 30676
strand -
CDS
ATGATCAAGCGGCAATCGGTTGCTGGGATCGGAGTGAGTGCCGCGCTTCTGATAGCCGTTTTACAGTTCGAGGGCTACACTGACAAAGCTGTGATACCAGTGCCAGGCGATGTGCCGACGATTGGTGCTGGTCGGACGGAGGGGGTTAAACTTGGGGATAAGACCGAGCCAGTTCGTGAGATGGTCTTTCTGCTGAATAACCTCGAAAATAAATATGCACGAAAAATCAGGGAATGTATACACGTCCCACTTCATGTGTACGAATTCGATGCCTACGTTTCCTTGTCCTACAATATCGGTACTTCTGCATTTTGTAAATCTACGCTGGTGAAAAAGCTAAACGCTGGGGATTATGCTGGAGCTTGTCAGCAAATTTTGGTCTGGGATAAATTTAAGGGCAAGCCGCTTCGCGGTCTAACCGTTCGCAGGCAGGAGGAATACGCAAAATGCTTAAACTCAGCGGATTAA
CDS Source ID
[NCBI]
CDS Source
LR796966 [NCBI]
CDS location
range 20840 -> 21307
strand +
CDS
ATGATCAAGCGGCAATCGGTTGCTGGGATCGGAGTGAGTGCCGCGCTTCTGATAGCCGTTTTACAGTTCGAGGGCTACACTGACAAAGCTGTGATACCAGTGCCAGGCGATGTGCCGACGATTGGTGCTGGTCGGACGGAGGGGGTTAAACTTGGGGATAAGACCGAGCCAGTTCGTGAGATGGTCTTTCTGCTGAATAACCTCGAAAATAAATATGCACGAAAAATCAGGGAATGTATACACGTCCCACTTCATGTGTACGAATTCGATGCCTACGTTTCCTTGTCCTACAATATCGGTACTTCTGCATTTTGTAAATCTACGCTGGTGAAAAAGCTAAACGCTGGGGATTATGCTGGAGCTTGTCAGCAAATTTTGGTCTGGGATAAATTTAAGGGCAAGCCGCTTCGCGGTCTAACCGTTCGCAGGCAGGAGGAATACGCAAAATGCTTAAACTCAGCGGATTAA
CDS Source ID
[NCBI]
CDS Source
LR797054 [NCBI]
CDS location
range 21671 -> 22138
strand +
CDS
ATGATCAAGCGGCAATCGGTTGCTGGGATCGGAGTGAGTGCCGCGCTTCTGATAGCCGTTTTACAGTTCGAGGGCTACACTGACAAAGCTGTGATACCAGTGCCAGGCGATGTGCCGACGATTGGTGCTGGTCGGACGGAGGGGGTTAAACTTGGGGATAAGACCGAGCCAGTTCGTGAGATGGTCTTTCTGCTGAATAACCTCGAAAATAAATATGCACGAAAAATCAGGGAATGTATACACGTCCCACTTCATGTGTACGAATTCGATGCCTACGTTTCCTTGTCCTACAATATCGGTACTTCTGCATTTTGTAAATCTACGCTGGTGAAAAAGCTAAACGCTGGGGATTATGCTGGAGCTTGTCAGCAAATTTTGGTCTGGGATAAATTTAAGGGCAAGCCGCTTCGCGGTCTAACCGTTCGCAGGCAGGAGGAATACGCAAAATGCTTAAACTCAGCGGATTAA
CDS Source ID
[NCBI]
CDS Source
LR797319 [NCBI]
CDS location
range 13631 -> 14098
strand +
CDS
ATGATCAAGCGGCAATCGGTTGCTGGGATCGGAGTGAGTGCCGCGCTTCTGATAGCCGTTTTACAGTTCGAGGGCTACACTGACAAAGCTGTGATACCAGTGCCAGGCGATGTGCCGACGATTGGTGCTGGTCGGACGGAGGGGGTTAAACTTGGGGATAAGACCGAGCCAGTTCGTGAGATGGTCTTTCTGCTGAATAACCTCGAAAATAAATATGCACGAAAAATCAGGGAATGTATACACGTCCCACTTCATGTGTACGAATTCGATGCCTACGTTTCCTTGTCCTACAATATCGGTACTTCTGCATTTTGTAAATCTACGCTGGTGAAAAAGCTAAACGCTGGGGATTATGCTGGAGCTTGTCAGCAAATTTTGGTCTGGGATAAATTTAAGGGCAAGCCGCTTCGCGGTCTAACCGTTCGCAGGCAGGAGGAATACGCAAAATGCTTAAACTCAGCGGATTAA
CDS Source ID
[NCBI]
CDS Source
LR797419 [NCBI]
CDS location
range 22682 -> 23149
strand +
CDS
ATGATCAAGCGGCAATCGGTTGCTGGGATCGGAGTGAGTGCCGCGCTTCTGATAGCCGTTTTACAGTTCGAGGGCTACACTGACAAAGCTGTGATACCAGTGCCAGGCGATGTGCCGACGATTGGTGCTGGTCGGACGGAGGGGGTTAAACTTGGGGATAAGACCGAGCCAGTTCGTGAGATGGTCTTTCTGCTGAATAACCTCGAAAATAAATATGCACGAAAAATCAGGGAATGTATACACGTCCCACTTCATGTGTACGAATTCGATGCCTACGTTTCCTTGTCCTACAATATCGGTACTTCTGCATTTTGTAAATCTACGCTGGTGAAAAAGCTAAACGCTGGGGATTATGCTGGAGCTTGTCAGCAAATTTTGGTCTGGGATAAATTTAAGGGCAAGCCGCTTCGCGGTCTAACCGTTCGCAGGCAGGAGGAATACGCAAAATGCTTAAACTCAGCGGATTAA
CDS Source ID
[NCBI]
CDS Source
LR798407 [NCBI]
CDS location
range 13634 -> 14101
strand +
CDS
ATGATCAAGCGGCAATCGGTTGCTGGGATCGGAGTGAGTGCCGCGCTTCTGATAGCCGTTTTACAGTTCGAGGGCTACACTGACAAAGCTGTGATACCAGTGCCAGGCGATGTGCCGACGATTGGTGCTGGTCGGACGGAGGGGGTTAAACTTGGGGATAAGACCGAGCCAGTTCGTGAGATGGTCTTTCTGCTGAATAACCTCGAAAATAAATATGCACGAAAAATCAGGGAATGTATACACGTCCCACTTCATGTGTACGAATTCGATGCCTACGTTTCCTTGTCCTACAATATCGGTACTTCTGCATTTTGTAAATCTACGCTGGTGAAAAAGCTAAACGCTGGGGATTATGCTGGAGCTTGTCAGCAAATTTTGGTCTGGGATAAATTTAAGGGCAAGCCGCTTCGCGGTCTAACCGTTCGCAGGCAGGAGGAATACGCAAAATGCTTAAACTCAGCGGATTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1ADQo) rather than this protein.
PDB ID
1ADQo
Method AlphaFoldv2
Resolution 80.10
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50