Protein

Protein accession
A0A6J5NMC9 [UniProt]
Representative
2Foe6
Source
UniProt (cluster: phalp2_19412)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKINKAGTDLIIRFEGGHILKSYRDPINIWTISVGLTRIYNRSVVESDIITLEESEKLFRIELNRFCDGVTRLLFTRLTENQFSALVSISFNIGLGALRGSTLLKMVNRNPNDPLIRNEFLRWNKINKIESRGLTRRRKAESDLYFS
Physico‐chemical
properties
protein length:147 AA
molecular weight:17049,5 Da
isoelectric point:10,06
hydropathy:-0,25
Representative Protein Details
Accession
2Foe6
Protein name
2Foe6
Sequence length
292 AA
Molecular weight
33120,16010 Da
Isoelectric point
9,46056
Sequence
MKLDINGINLIAELEGLKLKAYKDLGGIWTIGFGNTFYADGSKVKEGDVVTKEQAYYLFHLIATKFEKTINDNVKKPLTQNQFNSLFCFCYNLGQTAFINSTLLKLVNINPTDANIAKEFLKWNKIARVESKGLTNRRIKESALYYTKILFVLFLLTSCGTRKVQKSDTTEDIKAEVNVKVENNIKKSSDSFTEVVDNSEIITIEAIDTINPLIIGGVTYKNARLSYVKNKIRTNTTSKETVVDKGYTKVKEQIKVNKEQIKVNKERTTNPLLYLIFPLVIGIMLIFGKKFL
Other Proteins in cluster: phalp2_19412
Total (incl. this protein): 6 Avg length: 219,3 Avg pI: 9,55
Protein ID Length (AA) pI
2Foe6 292 9,46056
1LX5P 289 9,31886
ZNYb 292 9,59317
A0A345BPP4 148 9,47036
A0A6J5N192 148 9,37398
Similar Clusters

No similar clusters were found for representative 2Foe6.

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 2Foe6 (292 AA)
Member sequence: A0A6J5NMC9 (147 AA)
1 292 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage uncultured Caudovirales phage
[NCBI] 		2100421 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LR796667 [NCBI]
CDS location
range 19474 -> 19917
strand +
CDS
ATGAAAATAAATAAGGCTGGTACAGATTTAATTATTAGATTTGAAGGTGGTCATATATTAAAATCATATAGGGATCCTATTAATATATGGACTATATCTGTGGGTCTCACAAGGATCTATAACAGGTCTGTTGTTGAAAGTGATATCATAACACTAGAAGAGAGTGAGAAGCTCTTTAGGATTGAATTAAATAGGTTCTGTGATGGTGTTACTAGACTATTGTTTACTAGATTAACAGAGAATCAGTTTTCAGCCTTAGTATCCATAAGTTTTAATATTGGATTGGGAGCACTTAGAGGATCTACACTTCTTAAAATGGTAAATAGGAATCCAAATGACCCTTTAATTAGAAATGAGTTTTTAAGATGGAATAAAATAAATAAAATAGAATCAAGAGGATTAACAAGGAGAAGAAAAGCTGAATCAGACCTATACTTCTCATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0030430 host cell cytoplasm cellular component None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0044659 viral release from host cell by cytolysis biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2Foe6) rather than this protein.
PDB ID
2Foe6
Method AlphaFoldv2
Resolution 62.73
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50