Protein

Protein accession
V5UT96 [UniProt]
Representative
8yFyU
Source
UniProt (cluster: phalp2_14898)
Protein name
N-acetylmuramoyl-L-alanine amidase domain-containing protein
Lysin probability
100%
PhaLP type
VAL
Probability: 98% (predicted by ML model)
Protein sequence
MIGKVVLPATALWLLSEGLATRPAADGTLDAQKDAQGRLPEDPGFDKTTKGQYKPPEKAQGGILPQAASGGWINGPQSGYPVSLDGGRSTSFIGHGSEYVARKSNGGAFVVPFNTPATKTQPNLTSRRMGEAKSQGFSLPGFSSGGNTARSGAPSIKLPELPEFSRGGNLDKQIYLHWTATDYNYKKGPYNAVIQGDGKVYNDRPSDQVGGEHTWRRNSKGVGISMAAMSGYNWDSYGPKPIQIENMSKEAANVAKKWGWKPSDINIKRVMNHAEAASNKDGKSPTPNYGPTWWNGTGERSDLHKLKKSDKDGTGGDKLRAKIRKYMGGEDTIVPTAGLKPGDHGPATTGGSAKIASGDYALLQKLVLAEAGGEGHLGMALVARSVLNRAGLVQKGIVGPGIFMAESGSVKDIIMADNGGQYTPAKPGGSLFKNRSDADMLRAQKAIETARNPTGLRGYLESKNVPAEQINYLMGSTGFRNYDAAFTDPSQQVNEVKFGNHTFNTASNPNILTPVSEITGHGGTGGGHSSSPLESTPESGGYNYDIGTNGAVFTPSSADSMTTRLGVPSPKSNFQPGVGSNITSGKDQFKLQRHTQEVTTARQQTTQMQKDLISAVLTQVAGSNQSNNVAIQKANKMIQEIMSSAGSSTPTPVTTGSSKSDDGSTASLLNSFNNPLRGAFK
Physico‐chemical
properties
protein length:681 AA
molecular weight:71877,3 Da
isoelectric point:9,46
hydropathy:-0,61
Representative Protein Details
Accession
8yFyU
Protein name
8yFyU
Sequence length
757 AA
Molecular weight
79002,77850 Da
Isoelectric point
9,75563
Sequence
lsdetswwekllgfgqallgigtlilgirwlrnplkivtdfagvlkflannlfdakkklarragrrgrgggfvksaailgggiligagvnqamqggdnneggdspppekaqggklpeaatggfidgpqsgyrvsldggrstsfighgreyvarksnggafviplntpatktqphltqkrigeaksqgyrvpgfaaggkasgskqkgggkdskkgnasgiskfnkmmgqatsflgsigkktmkpvmnaaksvyrapgwmgfaqggnvrekykngevprsemkevtgyagygaagkgilhnsvadkfqsmieaakkdghplgindtyrtyedqvymkqtkgrlaatpgtsnhgyglaadlnyfdggykwlwanadkfgfrplsgwglspntpdkaeawhwenldgsgtadpnvktepagdaadagqqpvnapaqgygklldligkyesdssggydavnqigtsgghgvkgyagpfskmeqhggkkltsltvaevmqlqsgwdggmsdeewikkgklhavgryqiigptlaslvnkgivsksdkfneatqnklgialvkgrgndpaalqqewiglqkastqdiaaeiqaggdttsgghasvggrikpaggaqtppgssaggaggneaakiilggttqvtsgtgkpnynrvsskdlpeqaiartargsgsamtdatkerndarqkisdktqsmmneviskvsaannfnaqaikqaqqgiqqaaqqgggggqqqmmpsggkpkessasklgsqinplkqllr
Other Proteins in cluster: phalp2_14898
Total (incl. this protein): 12 Avg length: 898,2 Avg pI: 9,63
Protein ID Length (AA) pI
8yFyU 757 9,75563
1s0FO 979 9,83183
3outs 924 9,84937
4Sk21 924 9,87161
5dGAD 926 9,84292
7Z3NQ 740 9,83654
81v3p 936 9,93434
8I8xK 981 9,86174
8I8yh 982 9,85897
M1T2Q1 974 8,70770
M1UG82 974 8,70770
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_40218
2qjSX
 23 41,7% 541 1.731E-97
2 phalp2_21079
8LRzV
 133 30,4% 865 9.588E-63
3 phalp2_22754
8gQfh
 42 25,8% 770 1.943E-47

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Synechococcus phage S-MbCM100
[NCBI] 		1340812 Kyanoviridae > Acionnavirus > Acionnavirus monteraybay
Host Synechococcus sp. WH 7803
[NCBI] 		32051 Cyanobacteria > Oscillatoriophycideae > Chroococcales > Synechococcus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KF156340 [NCBI]
CDS location
range 9714 -> 11759
strand +
CDS
ATGATAGGCAAGGTTGTCCTTCCTGCTACTGCTCTCTGGTTACTTTCTGAGGGTTTAGCAACCCGTCCTGCTGCAGATGGCACTCTGGATGCCCAAAAAGATGCACAGGGGAGATTGCCAGAAGATCCAGGATTTGACAAAACAACTAAAGGACAATACAAACCACCCGAAAAAGCACAAGGTGGAATATTACCACAAGCAGCATCAGGAGGATGGATTAATGGACCACAATCAGGATATCCCGTATCATTGGATGGAGGGAGATCAACCTCGTTTATCGGACACGGATCCGAATATGTTGCTAGAAAGTCTAATGGGGGAGCTTTCGTCGTTCCTTTTAATACTCCTGCAACAAAAACACAACCAAATCTAACCTCTAGGAGGATGGGTGAGGCAAAAAGTCAAGGATTTAGTCTTCCTGGATTTTCTAGCGGTGGTAATACTGCAAGATCTGGTGCTCCTAGTATAAAATTACCAGAACTACCAGAATTTTCAAGAGGTGGTAACTTAGACAAGCAAATCTATTTGCATTGGACTGCTACTGATTATAATTATAAAAAAGGACCTTATAATGCAGTAATTCAAGGTGATGGAAAAGTATATAATGATAGACCTTCTGACCAGGTTGGAGGGGAGCATACCTGGAGACGTAATAGCAAGGGTGTAGGAATTAGCATGGCAGCAATGTCAGGTTATAACTGGGATTCCTATGGTCCAAAACCCATCCAGATTGAAAATATGTCAAAGGAAGCAGCAAATGTTGCTAAAAAATGGGGATGGAAACCTAGTGATATTAATATCAAGAGAGTGATGAATCACGCTGAAGCAGCGTCAAACAAAGATGGTAAGAGTCCAACTCCTAACTATGGTCCTACTTGGTGGAATGGTACGGGTGAAAGATCCGACTTACATAAGTTGAAGAAAAGTGATAAGGATGGCACAGGTGGTGATAAACTTCGTGCAAAAATTAGAAAATATATGGGTGGGGAGGACACAATAGTTCCTACTGCTGGATTAAAACCAGGCGATCACGGTCCAGCGACAACTGGTGGCAGTGCCAAGATTGCTAGTGGTGATTATGCATTACTCCAAAAACTTGTTCTTGCTGAAGCTGGAGGAGAAGGTCATTTAGGAATGGCATTAGTTGCACGATCTGTTTTGAACAGAGCAGGATTAGTCCAAAAAGGCATTGTAGGACCTGGGATCTTCATGGCAGAAAGTGGAAGTGTTAAAGATATTATCATGGCAGACAATGGCGGACAATACACTCCAGCAAAACCAGGCGGATCTCTATTCAAAAATAGAAGTGATGCTGATATGTTGAGAGCACAGAAAGCAATTGAAACTGCTAGGAATCCGACAGGTCTTAGAGGATATCTTGAATCTAAAAATGTTCCAGCAGAGCAAATTAATTATCTTATGGGTTCTACTGGATTTAGAAATTATGATGCTGCTTTCACAGATCCATCTCAACAGGTCAATGAGGTTAAGTTTGGGAATCATACATTCAATACTGCAAGTAATCCAAATATCCTCACTCCTGTAAGTGAAATTACTGGTCATGGTGGAACTGGTGGAGGTCATAGTAGTTCTCCTCTTGAAAGCACGCCTGAATCTGGTGGATATAATTATGATATCGGAACAAATGGAGCAGTATTTACGCCATCCTCTGCAGATAGTATGACTACTAGGTTGGGTGTTCCTTCTCCTAAAAGCAACTTCCAACCTGGTGTAGGTAGTAACATAACCTCTGGAAAAGATCAGTTTAAGTTACAAAGACATACACAAGAAGTAACTACTGCTCGTCAGCAAACCACTCAAATGCAGAAAGATTTAATTTCTGCAGTATTGACACAAGTTGCTGGATCTAATCAATCTAATAATGTAGCAATTCAGAAGGCAAATAAAATGATTCAAGAAATAATGAGTTCCGCTGGATCAAGCACACCAACTCCAGTAACAACTGGTAGTAGTAAATCTGATGATGGTAGTACTGCATCATTACTAAATTCTTTCAATAACCCCCTTAGAGGTGCGTTCAAATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8yFyU) rather than this protein.
PDB ID
8yFyU
Method AlphaFoldv2
Resolution 62.68
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50