Protein

Protein accession
S0A321 [UniProt]
Representative
wgKr
Source
UniProt (cluster: phalp2_11495)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRTAILIGHTKNSPGACSPHGLPCEFDFNKSIAIAAAKKNCGITVFENGSYDKGYYEMTKATAKELNEFKPDLILELHYNAADPSAHGSEALYYFKNKKTKALGYYFTKLLQLHMGYRDRGAKALVNKNDRGYWSVFLPDAPSLILEPFFGSNKSDVQRMNKDKYIDVILKTIKYYETIK
Physico‐chemical
properties
protein length:180 AA
molecular weight:20397,2 Da
isoelectric point:9,15
hydropathy:-0,45
Representative Protein Details
Accession
wgKr
Protein name
wgKr
Sequence length
171 AA
Molecular weight
19217,41770 Da
Isoelectric point
7,00367
Sequence
MNDNQIAIVIGHDYISKGAYSEYINQYEFDYNIGVAQITGLDTYTHSPSSSYTHKMQKTYRHLDNYSLTLEMHFNAASEGVQGVEALYYGGNMEGKRIAELYCDLVAKEYGIRNRGAKPLNSDKDRGFRAVASGKPTGLILEPFFGSNSKCKAFKDKERHAALMCDFISKI
Other Proteins in cluster: phalp2_11495
Total (incl. this protein): 11 Avg length: 181,5 Avg pI: 8,34
Protein ID Length (AA) pI
wgKr 171 7,00367
1lhn3 197 6,52463
1lyXH 197 7,60673
2kx7 176 9,25839
XjZ4 192 6,44994
uy3r 172 9,23434
S0A0K5 180 9,15382
R9ZY40 180 9,14196
A0A6G6XU35 172 9,03449
R9ZZI3 180 9,15382
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_7941
wIlS
 251 42,4% 179 2.022E-58
2 phalp2_40411
4aXVp
 16 30,0% 163 6.290E-28
3 phalp2_11016
4Prl3
 67 32,4% 179 1.613E-27
4 phalp2_36343
kBxJ
 714 30,0% 193 1.985E-26
5 phalp2_6329
79LaP
 54 28,1% 185 2.439E-25
6 phalp2_21852
4t88M
 271 26,8% 164 8.548E-25
7 phalp2_31845
4B5i6
 56 30,2% 175 4.010E-21
8 phalp2_21590
2ns10
 22 28,1% 160 5.943E-19
9 phalp2_39328
4t9kP
 35 29,1% 151 1.516E-18
10 phalp2_5086
1FA9p
 33 25,1% 175 1.344E-17

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): wgKr (171 AA)
Member sequence: S0A321 (180 AA)
1 171 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Cellulophaga phage phi18:2
[NCBI] 		1327995 Helsingorvirus > Helsingorvirus Cba181
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
KC821627 [NCBI]
CDS location
range 37454 -> 37996
strand +
CDS
ATGAGAACAGCGATATTAATAGGCCATACGAAGAATAGCCCAGGAGCATGCAGCCCGCACGGTTTGCCTTGTGAGTTTGATTTTAATAAATCAATTGCAATTGCAGCGGCCAAAAAAAATTGTGGAATTACGGTTTTTGAAAATGGATCTTATGACAAGGGATATTATGAAATGACAAAGGCAACGGCTAAGGAGCTCAATGAGTTTAAGCCTGATCTTATATTGGAATTACATTATAATGCAGCGGATCCCTCCGCTCATGGCTCAGAGGCTTTGTATTACTTCAAAAATAAAAAGACAAAGGCTCTTGGTTATTATTTCACAAAACTTTTACAACTCCATATGGGGTATAGGGACAGAGGGGCAAAGGCTTTAGTTAATAAAAATGACAGAGGCTATTGGTCCGTATTTTTGCCAGATGCACCATCATTGATCTTGGAGCCTTTTTTCGGTTCCAATAAATCCGACGTTCAAAGAATGAATAAGGATAAGTATATTGATGTAATCCTTAAAACTATAAAATATTATGAAACGATTAAGTAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000351f022_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (wgKr) rather than this protein.
PDB ID
wgKr
Method AlphaFoldv2
Resolution 93.71
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50