Protein

Protein accession
Q4ZCS7 [UniProt]
Representative
7spQX
Source
UniProt (cluster: phalp2_11347)
Protein name
ORF013
Lysin probability
100%
PhaLP type
endolysin
Probability: 64% (predicted by ML model)
Protein sequence
MLKKKLIDKVKSWFEDFGGGGDGSYLFEYPIWQRFGRYTGGLNFNDGRHYGIDFGMPTGTNVYAVKGGIADKVWTDYGGGNSIQIKTGANEWNWYMHLSKQLARQGQRIKAGQLIGKSGATGNFVRGAHLHFQLMQGSHPGNDTAKDPEKWLKSLKGSGVRSGSGVNKAASAWAGDIRRAAKRMGVNVTSGDVGNIISLIQHESGGNAGITQSSSLRDINVLQGNPAKGLLQYIPQTFRHYAVRGHNNIYSGYDQLLAFFNNRYWRSQFNPRGGWSPSGPRRYANGGLITKHQLAEVGEGDKQEMVIPLTRRKRAIQLTEQVMRIIGMDGKPNNITVNNDTSTVEKLLKQIVMLSDKGNKLTDALIQTVSSQDNNLGSNDAIRGLEKILSKQSGHRANANNYMGGLTN
Physico‐chemical
properties
protein length:408 AA
molecular weight:44818,0 Da
isoelectric point:9,95
hydropathy:-0,59
Representative Protein Details
Accession
7spQX
Protein name
7spQX
Sequence length
1867 AA
Molecular weight
203163,15520 Da
Isoelectric point
6,54878
Sequence
MASKKPLGNMVVELDLNSSAFSKGLDGAKKAVTSSMKSMKSQMKIMDASGDKMGKLEAKQSGLTRTIEAQEEEVRRLQDAYDNSFDANGNATEATAKYANKLNDAQGRLASYRKQLSDVGQEIASYKKQLELAENPMYKAGQSMQEAGNKMQGFGSNMMSVGSKISGFGSSLTKNITKPILGIGAALGGLTLGLGMKRLVGIDDAKAKLEALGNSTEEVDEIMQNADKAIEGTSMRLDETATVAASASAAGVDAGEDLTRYLGLTADAASVAGTSMSDMGNVLNKATTQGKAQNDVLQQMSEQGLPVYQWLGEEANKAGDEIFQMASDGKISTEMLLDAIENNIGGAAQIMGEKSFTSALQNMSTYLGHVGAAFLDGKGEGEGFFSAIKPLMVDFSEYLQSITPQAEELGEKFGQSFTNMIDKLKEAKSWYDNLSDGQQDLIKKVATFGTVGLVALGPVAQLIGNLTTVVGGATWAFGGLIKGMGKGLKKVAPLFTPILDQLKLLPLRFQMLSLSIKESGGLLAWLKGGFAALNWPITLIVGAIAAVTAGLVVLYNKSETFREIVNTAVEAVKNKFLQFKEVVSTLFGLFTGGLDFTQAKEQLNGVVSESTVQRFQSVRNFIEKIKLSFEALGAVISDEAGIGQLKNLFGDTFSDETLGRILIVGETVRNFVDMVKQKFAEFAEALSQAFQGNFEPLLEFIQQLIPKIVMMLIGGLPALIYTGMSLITKLAEGMGISVPELIEKVAGIITTMLMKFTEALPRIIETGANIILKLINGFTQMLPNLIEAATGIISTILQTISEILPRVIYAGVSILTSLISGIIDTLPQIINTSVKMINVLVNTLINLLPKIINAGIKILKALINGILKILPQLINAGVKLITTVASAVIDNLPKIIDAGIEILLALIDGIIKILPQLIEAGLKIIVSLFKALIDNLPKIIEAGVELLFALIDGLIKTIPELVKAIPKIVKAIFDAFKDVDWAGLGKDILDGILEGLKDIGSNVWDSVKDVGNNIKDSFADFFDIHSPSRVMADLAKFLPEGIAKGITDNQDVVAQAMQMLNGMMRDSVQQSATVDVEANANQDDENANTANPLEKIMKGFAEQIPQAQEKVKQFIAQWNQLFIANDEVMLKIGFAWLNRLLQGANEAYPKIVERVKQLINQINTIVKNNYEPMQNQGRTLLKKLLDGWNSVYDAMVNRVKQLISQINKLIQNNYSPMYNQGRTWLQRLLDGFNSLYSQMINRIKQLISQINKLIQNNNKPMYNQGRRWLQELRNGFNSLYDSFMSLISRLCSEAVDRIRDKHGDFYNAGKYLIEGLKDGISAMKGPIGDIMNDVANKMIGGIANGVSGVRSGVNHILKEVDSDKRIDEWDVPKYAKGTKGGGHPADGPAIVNDQSGPISRRRELIQNPDGSTFMAKAKNSLVNLQKGARVFNADMTNKLKKSGHIPHYKDGTDDTDVFDLVDDKDKFYKFIKDKINLDNVGEPWKDMSKKASKMMIDAAYDMVEDEASFGMFDGKMDKSGKWKVYNYLWDVAQKVMDKFTGMSVTSGYRDGDPNHHGKHQAIDIAYPASANGSSKYLKPANYAFDKFKDQIAYVITQGRVKDRVGSSGHGPSKSWMNWGSSDHDDHLHLSGQYGPGDVGKGGGKNGDWTEAINQAAKRMKVKPTKKQISGINSMIQAESGGDEKVSQQIHDANSTNGSGGAKGLLQYIQSTFDAYAVKGHKNIWSGLDQLMAFFNNSNWKSAIAPSGGWGPTGSRRFEHGGLINRHMVAEMGEGNKPEMVLPLTNKARSLDLMAKAMHIMGVDGGKTTTTGQSYDDADLIALLIEQHKETVSVLKAIAYKDTTVDADSLTDYTNDRLGKQLKRLGVV
Other Proteins in cluster: phalp2_11347
Total (incl. this protein): 5 Avg length: 1425,4 Avg pI: 8,17
Protein ID Length (AA) pI
7spQX 1867 6,54878
1QQ3q 1907 9,61444
7cPSB 1448 5,35778
7wcEs 1497 9,38726
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_33306
6eT1I
 21 37,5% 1685 0.000E+00
2 phalp2_7794
7rQ6d
 55 24,9% 1851 6.122E-134
3 phalp2_6330
7c3Ed
 8 20,1% 1720 7.129E-88
4 phalp2_8198
7fTRt
 93 21,9% 2038 8.348E-64
5 phalp2_22501
1enlE
 152 22,3% 1866 5.188E-62
6 phalp2_2887
ugAr
 2 23,4% 1331 2.914E-59
7 phalp2_18794
1bXeZ
 6 21,4% 1163 8.312E-45
8 phalp2_18582
7iQOB
 13 19,0% 2140 3.372E-31
9 phalp2_9304
7rjcd
 9 21,9% 1702 4.269E-28
10 phalp2_17324
4kx54
 4 18,8% 1206 2.137E-11

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Staphylococcus phage 3A
[NCBI] 		2952374 Triavirus > Triavirus tv3a
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
AY954956 [NCBI]
CDS location
range 13581 -> 14807
strand +
CDS
TTGCTCAAAAAGAAATTAATAGACAAAGTAAAATCGTGGTTTGAAGATTTTGGTGGTGGAGGCGATGGAAGCTATCTATTTGAATATCCAATCTGGCAAAGATTTGGACGCTACACAGGTGGACTTAACTTTAATGACGGTCGTCACTATGGTATAGACTTTGGTATGCCTACTGGAACAAACGTTTATGCCGTTAAAGGTGGTATAGCAGATAAGGTATGGACTGATTACGGTGGCGGTAATTCTATACAAATTAAGACCGGTGCTAACGAATGGAACTGGTATATGCATTTATCTAAGCAATTAGCAAGACAAGGCCAACGTATTAAAGCTGGTCAACTGATAGGGAAATCAGGTGCTACAGGTAATTTCGTTAGAGGAGCACACTTACATTTCCAATTGATGCAAGGGTCACATCCAGGGAATGATACAGCTAAAGATCCAGAAAAATGGTTGAAGTCACTTAAAGGTAGTGGCGTTCGAAGTGGTTCAGGTGTTAATAAGGCTGCATCTGCTTGGGCAGGCGATATACGTCGTGCAGCAAAACGAATGGGTGTTAATGTTACTTCGGGTGATGTAGGAAATATCATTAGCTTGATTCAACACGAATCAGGAGGAAATGCAGGTATAACTCAATCTAGTTCGCTTAGAGACATCAACGTTTTACAGGGCAATCCAGCAAAAGGATTGCTTCAATATATCCCACAAACATTTAGACATTATGCTGTTAGAGGTCACAACAATATATATAGTGGTTACGATCAGTTATTAGCGTTCTTTAACAACAGATATTGGCGCTCACAGTTTAACCCAAGAGGTGGTTGGTCTCCAAGTGGTCCAAGAAGATATGCGAATGGTGGTTTGATTACAAAGCATCAACTTGCTGAAGTGGGTGAAGGAGATAAACAGGAGATGGTTATCCCTTTAACTAGACGTAAACGAGCAATTCAATTAACTGAACAGGTTATGCGCATCATCGGTATGGATGGCAAGCCAAATAACATCACTGTAAATAATGATACTTCTACAGTTGAAAAATTGTTGAAACAAATTGTTATGTTAAGTGATAAAGGAAATAAATTAACAGATGCATTGATTCAAACTGTTTCTTCTCAGGATAATAACTTAGGTTCTAATGATGCAATTAGAGGTTTAGAAAAAATATTGTCAAAACAAAGTGGGCATAGAGCAAATGCAAATAATTATATGGGAGGTTTGACTAATTAA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi0000505938_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7spQX) rather than this protein.
PDB ID
7spQX
Method AlphaFoldv2
Resolution 52.69
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50