Protein

Protein accession
P89923 [UniProt]
Representative
7qQKH
Source
UniProt (cluster: phalp2_15054)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MYNEVTVHAGHTQGGGASGNGYEESAVARQFLPVLLNAFKAVGQKVTDVTDNVSTTQNANLNRLVASCNARPAAGRLDISLHFNASDDASATGVEVLYYDQVNLADRVSESISRVTGLRDRGPKVRKDLAVLARTNAPAILIELAFITNAEDMRKFFNNMQAIANAIVQTVTGKSVNIDPPVAKRTATIITTGGLGQEAAHQAIDMLFAKGWFGKVTVQSDGLAVLETGGLSGDKLQAAREYFTWRGWWTFDTVIEY
Physico‐chemical
properties
protein length:257 AA
molecular weight:27678,8 Da
isoelectric point:6,10
hydropathy:-0,10
Representative Protein Details
Accession
7qQKH
Protein name
7qQKH
Sequence length
318 AA
Molecular weight
35771,41430 Da
Isoelectric point
6,01580
Sequence
MSFQRFTSNAGHSYHTDGAQGNGYSEHAEAMKYNNEFIKQMKQVGYTVTNTTSEAKGQQAILSEQAHKANEVDRTGRLDVSFHFNSASASATGVEVLYYDQEVLASQVSQAIANALGIRNRGAKENKGLYFLANTNAPAILIEVAFISNAGDMKQATSKRVQAVAAIVKALTGKETPSAGFTGTWWRYARATHHIRTRPDWDSPVAFDIPNYYAVNMNYDKRENEFVEIEFQGQKGWFKDSLTEYWFEEKPTETYVVTAETVHFRDQQDWDSPVVQTKKKGDTVEVLREMDKPGWLQVILTEGVIGYIPDAPHYVKKV
Other Proteins in cluster: phalp2_15054
Total (incl. this protein): 6 Avg length: 333,2 Avg pI: 7,50
Protein ID Length (AA) pI
7qQKH 318 6,01580
A0A7R7G2D5 332 6,59249
A0AAE7SS33 364 8,89788
A0AAE7VHI0 364 8,69384
A0AAE7VHL0 364 8,69384
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11988
35NoL
 2 31,2% 205 1.712E-19
2 phalp2_7714
6PwWD
 2 28,2% 209 7.674E-13
3 phalp2_29154
7mKv1
 17 28,7% 226 2.489E-09

Domains

Domains [InterPro]
Ami3
Unannotated
Representative sequence (used for alignment): 7qQKH (318 AA)
Member sequence: P89923 (257 AA)
1 318 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage 12826
[NCBI] 		57476 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
Y11476 [NCBI]
CDS location
range 683 -> 1456
strand +
CDS
ATGTATAATGAAGTTACTGTCCATGCCGGGCATACACAAGGCGGAGGAGCTAGTGGTAACGGGTATGAGGAGTCGGCGGTTGCCCGTCAATTCCTCCCTGTCCTATTGAATGCTTTTAAAGCAGTCGGACAGAAGGTAACAGACGTAACTGACAACGTAAGCACAACGCAGAACGCTAACCTTAATAGATTAGTAGCAAGTTGTAATGCTCGACCTGCTGCGGGGCGCTTGGATATCTCATTACACTTCAACGCTTCAGATGATGCAAGCGCAACAGGTGTAGAGGTATTGTATTACGACCAAGTTAACCTTGCTGACCGTGTATCCGAAAGTATCTCACGTGTAACAGGACTGCGTGACAGAGGACCAAAGGTAAGAAAAGACTTAGCTGTTCTTGCTCGTACGAATGCGCCTGCAATCCTTATCGAACTTGCATTCATTACGAATGCAGAAGACATGAGGAAGTTCTTTAACAATATGCAAGCTATTGCGAATGCTATCGTACAGACTGTTACAGGGAAGTCAGTTAACATCGATCCACCTGTTGCGAAACGTACCGCTACTATTATTACTACTGGTGGTCTTGGACAAGAAGCAGCGCACCAAGCAATTGATATGTTATTCGCTAAAGGATGGTTCGGTAAAGTAACCGTACAGTCCGATGGGTTAGCCGTGCTAGAGACTGGTGGTCTATCAGGAGACAAGCTACAAGCTGCCCGTGAGTACTTCACTTGGCGTGGATGGTGGACATTTGACACAGTGATTGAATATTAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. N/A UniProt

Tertiary structure

PDB ID
upi00000ee7ab_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7qQKH) rather than this protein.
PDB ID
7qQKH
Method AlphaFoldv2
Resolution 93.63
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50