Protein

Protein accession
J7KIY0 [UniProt]
Representative
6sPcb
Source
UniProt (cluster: phalp2_3825)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MATYQEYKSRSNGNAYDIDGSFDAQCWDGYADYCGFLGVPYSNCTNTGYARDIWEQRHENGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGGGYGWFLGQNQGGANGAYNLVKIPYSATYPTAFRPKVFKNAVTVTGNTGLNKGDYFIDVSAYQQADLTTTCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSALAQREADLFLSNLPSKKVSYLVIDYEDSASADKQANTNAVIAFMDKIASAGYKPIYYSYKPFTLNNIDYQKIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAGGLDKNIVLLADDSSKMDIPKVDKPQELTFYQKLATNTKLDNSNVPYYEATLSTDYYVESKPNASSADKEFIKAGTRVRVYEKVNGWSRINHPESAQWVEDSYLVNATDM
Physico‐chemical
properties
protein length:443 AA
molecular weight:49529,3 Da
isoelectric point:4,82
hydropathy:-0,43
Representative Protein Details
Accession
6sPcb
Protein name
6sPcb
Sequence length
753 AA
Molecular weight
84128,52630 Da
Isoelectric point
6,22855
Sequence
MVDYKTFKSKWMNKGTDVDGSFGFQCWDLYAQWCKENGVPYANCTVSGYVKDLWEQRRTNGILKYFDEVEMMEEGDVAVFKEVAGWTPVSHVALFDSDAGGGFGWFFGQNQGSQLTNPAGGSSANLVKLPYSATYPTAFRLKKKATQAKTQGGNTAVAVPAKNINGEIYSGLITGVDPNPMNCDGNRVKIDRIVIHHNATTNDAVARHTWYVSSGHGTSAHYQVTPDKIWGCVGENYVAYHAGNYPMNQRSIGIEHLNNTGAPTWTIAEETYRNSAKLIRDICERYNIPIDRQHILKHGEVSSTACLPVENTELLTKQGWVSLKDIQVGDEIATYRLDDGSIIFDTVYNKVEPHIKDTWLFRDVEVTADHRMLWKSQAGKTYKVSEAKDMFSNKGTLVFPNAGNYVAEGLPVSDTYLQYLVAVQADGHYMKDNRTINKNPFGIEFHIKKGRKVELLTDILDELGKEYTFAEKKDGTYSFRIYGAEEVEEVEQYLDNKKFSWKFLEMSERQAELFLDYILDFDGCRAGNDYSSTLSQNIDVVQAIASLHNKGSRTSTEGNRLYFTNSTRSVNSTGTLAKSAQRKHGKLVSCVSVTSGLILIRQHGRTTIVGNCPGGIDIDRLVAMARGAEYVTPSKATPRPSAPGKMQHAYQVDDLKYVNGLWQVYCKELVPVAFNWTDNGIAVEDIIITDKNGAKLPDQMTHVGDYFVFDQTATGDTGVGGVGDGNYYWRKFKLRTSGEIWLSAWNLNHLLFG
Other Proteins in cluster: phalp2_3825
Total (incl. this protein): 23 Avg length: 594,6 Avg pI: 5,63
Protein ID Length (AA) pI
6sPcb 753 6,22855
5OeRC 753 6,12738
5ZiIi 1047 6,69600
60MiV 750 6,36639
6q4Hl 708 6,09572
6uVt4 752 6,28062
6v4Am 750 6,61239
80Q2a 752 6,30955
8kORg 571 6,29523
8qTJP 750 6,61148
CLRU 751 6,48717
A0A4D6B9M7 447 4,98617
A0A4D6A2N2 444 4,97207
Q5MY96 443 4,87584
A0A4D6A093 447 4,87920
A0A4D6B8X9 444 5,04261
A0A4D6AH66 447 4,90767
A0A4D6AQ58 447 4,75784
A0A4D6ADQ2 444 5,04261
A0A4D6B578 444 5,04261
A0A4D6B9B0 444 5,02726
A0A4D6BAR8 444 5,04261
Similar Clusters

No similar clusters were found for representative 6sPcb.

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptococcus phage LYGO9
[NCBI] 		1225805 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
JX409894 [NCBI]
CDS location
range 7743 -> 9074
strand -
CDS
ATGGCAACTTATCAAGAATATAAAAGCAGGTCAAATGGTAACGCTTATGATATTGATGGTTCGTTCGATGCACAATGCTGGGACGGTTATGCAGATTACTGTGGATTTTTAGGTGTACCGTACTCAAACTGCACAAATACAGGATACGCAAGAGACATCTGGGAACAGCGCCACGAAAATGGTATCTTAAACTACTTTGACGAAGTAGAGACTATGCAAGCGGGAGATGTCGCTATTTTTATGGTAGTTGCAGGTGTTACACCGTACAGTCATGTTGCTATCTTTGATAGTGATGCTGGTGGTGGATATGGCTGGTTTTTGGGGCAAAATCAAGGCGGTGCTAATGGCGCATACAACCTTGTAAAAATTCCATACTCCGCGACTTATCCTACTGCATTTAGACCAAAAGTTTTTAAAAATGCAGTTACTGTTACAGGTAATACTGGCTTAAATAAAGGTGATTATTTTATCGATGTATCAGCTTATCAGCAAGCAGATTTAACAACGACTTGTCAGCAAGCTGGCACTACTAAAACGATTATCAAAGTATCCGAGTCACTCGCTTGGCTGTCTGACAGACATCAACAACAAGCAAACACAAGCGACCCAATTGGCTATTACCACTTTGGACGTTTTGGCGGTGATAGTGCTTTAGCGCAACGGGAAGCAGACTTATTTTTGTCTAACTTACCAAGCAAAAAAGTATCATACTTAGTCATTGACTATGAAGATTCCGCAAGCGCAGACAAGCAAGCTAACACAAATGCAGTTATTGCATTTATGGATAAAATCGCTAGCGCTGGATATAAGCCTATTTATTACAGCTATAAACCATTTACGCTTAATAATATTGATTATCAGAAAATTATCGCTAAGTACCCTAATAGCATTTGGATAGCTGGTTATCCAGACTACGAAGTACGAACAGAGCCGCTGTGGGAGTTCTTCCCTTCAATGGATGGTGTTCGCTGGTGGCAGTTTACAAGTGTAGGAGTAGCAGGTGGTTTAGATAAAAATATTGTGTTGTTAGCAGATGATAGTAGCAAAATGGATATACCTAAGGTTGATAAGCCACAAGAACTTACTTTTTATCAAAAACTAGCTACTAACACTAAATTAGACAACTCAAATGTACCTTATTACGAAGCAACTCTTAGCACAGACTATTATGTAGAGTCTAAGCCAAACGCAAGTAGCGCTGATAAAGAATTTATCAAGGCAGGAACTCGTGTAAGAGTTTATGAAAAAGTGAATGGATGGTCACGCATTAACCATCCAGAGTCGGCGCAATGGGTAGAAGATAGCTACTTAGTTAACGCAACAGATATGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

PDB ID
upi00027f0476_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (6sPcb) rather than this protein.
PDB ID
6sPcb
Method AlphaFoldv2
Resolution 87.72
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50