Protein

Protein accession
I3ULH9 [UniProt]
Representative
20UhE
Source
UniProt (cluster: phalp2_10421)
Protein name
Peptidase C39-like domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 94% (predicted by ML model)
Protein sequence
MLPLVRSFLAFGDIILSKILRVLNIEDPFLSKMEIDLHNFFRFYKHENPQHVAAVQWLEDNLPKEYLDDNSEWVKIFRKPAPGPAGITNPLKVPYYPQTDNYTNAERTCNSSSCAMCLEYFKPGTLPAGPKGDDAYVKEVFKIGDTTDHAVQTKVLEKFGVKSHFSYNLSFADLDKQLAAGKPVVIGILHRGTLAAPKGGHMCVVIGKKGEDYIVNDPYGDLNDGYSSDVMNGKGAVYKKSHLAKRWCPGGNDGWGRIFTQDLPK
Physico‐chemical
properties
protein length:265 AA
molecular weight:29586,5 Da
isoelectric point:7,64
hydropathy:-0,37
Representative Protein Details
Accession
20UhE
Protein name
20UhE
Sequence length
297 AA
Molecular weight
33219,71570 Da
Isoelectric point
5,07535
Sequence
MRIDFSNFFKYYNSDLKNHIESIDLLEREIEKVAPHLLEDEAEWVKLYRNTPEVDKPDKVIALPVPYFPQTDNYTQPERTCNSSSCAMCLEYFRPGTLVGSKGDDAYIRKVFAVGDTTDHSVQTKVLADYGVDSEFNYSLSFDNLDHELENKRPVVIGILHRGTLAHPTGGHMVVVIGKTAEGDYICHDPYGDLNDGYTTNVYNGQSVVYKRSVLESRWTPDGPTSGWGRTFQAKVIAKKSEEGKLPSAGVELIKEFEGLHVVKSDGMIHAYPDPLSGGEPWTIGWGSTRDLDGSAF
Other Proteins in cluster: phalp2_10421
Total (incl. this protein): 95 Avg length: 263,3 Avg pI: 7,12
Protein ID Length (AA) pI
20UhE 297 5,07535
13U92 231 8,29407
14fbH 232 8,89427
158xq 228 8,54143
15qUm 237 6,60056
1NQPK 226 6,03087
1ixxU 292 8,64935
1ke8r 310 9,18431
1kyZa 278 6,75215
1s1wg 407 5,12156
1tejg 405 5,05437
1wUIU 226 8,22663
22hTl 229 8,73787
25wHT 244 6,70253
274Ic 233 5,88274
27MpO 236 9,12468
27gMK 228 6,95967
2JNw9 308 6,02285
2cUjH 280 6,74982
2d5hS 280 6,35786
2nhI8 235 4,90074
2s8nA 405 5,33254
31Jx1 226 7,68482
31oTh 226 6,48615
3Xhao 236 9,21261
3aRf3 315 4,83412
429HQ 226 6,22287
46Poa 229 7,00554
46SnK 226 6,14125
46Y9S 278 7,69187
46b3Z 230 7,66834
46bTW 280 6,59136
473EA 280 6,06867
48hq5 226 6,34428
48jOg 278 6,35837
496hE 278 7,69591
4A1s9 230 8,84411
4NZQ2 279 8,12097
4WPVw 235 6,53264
4X5nK 236 6,60130
4b5u0 233 6,44716
4hM3v 405 5,34920
4iEaQ 405 4,95343
4iG71 235 5,17447
4ijcc 405 5,28508
4nAjP 238 8,37826
4qEAo 192 6,64876
4rWYv 332 5,86342
4tdi2 405 5,15282
4uG2n 271 7,65214
4zwLt 233 8,24926
51iK3 232 8,46768
54cQD 231 8,65831
565yW 274 8,06308
5BuJ2 231 8,36872
5GPxY 405 5,25411
5Hk8h 230 8,58011
5cvuh 228 6,51485
5hziE 230 8,52493
5kAva 228 6,52485
5mlcY 231 8,30412
5wFGx 237 6,59613
5zur2 230 8,52493
6Blo3 232 9,05963
6LDpS 230 7,63179
6LNTt 233 6,90363
6LUeZ 236 6,23986
6LVoD 236 7,72166
6LnQz 230 7,64089
6Mhzm 238 7,04414
6x9ZF 233 8,43048
7ghx 231 7,69625
80t28 229 6,94984
8Bl5A 236 9,41969
8Bld0 231 7,69886
8HjPI 247 5,09933
8bada 279 8,12097
8jFZm 240 7,72586
8msUL 278 7,11638
8nDWz 230 8,59816
8o4af 230 8,53363
8ucU 405 5,19300
AEFO 230 8,77603
C8uN 231 6,51167
PFuX 234 7,69568
TmUE 233 8,21161
Ya6R 405 5,12082
ijC1 232 7,68369
iyoT 231 7,68284
x3N0 240 8,62698
Q5GQI4 231 6,30324
A0A1D8KUP2 247 5,09933
A0A1D8KU76 235 5,01731
A0A9X9JM91 393 8,76050
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_9409
8H6wD
 41 77,1% 297 6.659E-181
2 phalp2_29834
276so
 38 46,1% 184 7.183E-63
3 phalp2_27442
7D9tM
 13 33,0% 284 5.743E-36
4 phalp2_4465
3aWb1
 922 29,3% 242 1.743E-30
5 phalp2_37765
4p7Ry
 12 26,6% 323 1.200E-24
6 phalp2_10615
2jt7K
 3 23,7% 248 2.813E-22
7 phalp2_5654
4rudF
 12 24,5% 187 3.436E-17
8 phalp2_84
4WuCJ
 39 29,6% 189 6.234E-17
9 phalp2_15779
3XLuq
 27 20,8% 201 8.413E-06

Domains

Domains [InterPro]
Unannotated
PET_C39
Unannotated
Representative sequence (used for alignment): 20UhE (297 AA)
Member sequence: I3ULH9 (265 AA)
1 297 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF13529

Taxonomy

  Name Taxonomy ID Lineage
Phage Synechococcus phage S-CBM2
[NCBI] 		351708 Kyanoviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
HQ633061 [NCBI]
CDS location
range 105158 -> 105955
strand +
CDS
ATGCTGCCACTGGTCAGATCATTCCTGGCATTTGGTGACATAATACTGTCAAAAATATTGAGGGTCCTAAATATTGAGGACCCTTTTTTGTCTAAAATGGAAATCGATCTTCATAATTTTTTCAGATTTTATAAGCATGAAAATCCACAGCACGTAGCAGCAGTGCAGTGGCTTGAAGATAATCTCCCCAAAGAATATCTTGATGATAATTCTGAGTGGGTGAAGATTTTTAGGAAACCTGCACCTGGACCAGCTGGTATTACCAATCCACTTAAGGTTCCTTACTACCCTCAAACTGACAACTATACAAACGCAGAACGTACATGTAACTCGTCTTCCTGTGCTATGTGTCTAGAGTATTTCAAACCAGGCACACTTCCAGCAGGTCCTAAGGGAGATGATGCTTATGTTAAAGAAGTCTTTAAGATCGGTGACACTACTGACCATGCTGTTCAGACTAAAGTTCTAGAAAAGTTTGGTGTTAAATCACACTTCTCATACAACCTATCATTTGCTGATCTCGATAAGCAACTTGCTGCTGGTAAACCAGTAGTAATTGGTATCCTCCACAGAGGTACTCTTGCTGCTCCTAAAGGTGGTCACATGTGTGTAGTCATTGGCAAGAAGGGTGAAGACTATATCGTTAACGATCCTTATGGTGATCTGAACGATGGTTATTCTTCCGATGTCATGAATGGTAAGGGTGCTGTCTACAAGAAGTCTCACCTTGCTAAGCGTTGGTGCCCTGGTGGTAACGATGGTTGGGGTCGTATCTTTACTCAAGACCTCCCAAAGTAA

Gene Ontology

No Gene Ontology terms available.

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi00026334df_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (20UhE) rather than this protein.
PDB ID
20UhE
Method AlphaFoldv2
Resolution 89.91
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50