Protein

Protein accession
E3SLR0 [UniProt]
Representative
3L6yL
Source
UniProt (cluster: phalp2_5188)
Protein name
Lysozyme
Lysin probability
98%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MATVKKGAKLDFYKFVDPNAGASTTSRANAKGGNRELTTVIKQNTRAINSMGRVVNSIGSTIVSIKDVQMRLLKIDEERLKKASFVPKYTKKQPPRKMKAFDSLFKGKIPGFFESLAKLASALIKFFLVLPALKWLSNPENQDKVVKGLEVLAKVFKFIASVAKFAFVNTIEGLYDLLKEDATWMERIGGFTRALAGLGTAFLALNFLTNPMGVIKTFSSVLLFFHKGLLAAFAKLATHPLIAGAALFLLPKYADQIPGLVNKNEEAIAEGLETTTNESGDTIIAESDEKAQRIADLKKQKEDLSLLDRLFGKGKEIEELIYYLETGKTKSYGFFENGGYLDGYAKGGWISGPQSGYPVSLDGNKPDFIGHGTEYVAQKSDGGAFIVPFDTPATKKDPDLTSRRMTEARLLGFFEEGGGYDKFAKRMIKIHEGFSPTAIPEPNGGMSIGYGHYIKPSDNFPPTISRAFANQLFKQDYKDHKNAAMKIPGFGKSSPQQKAALVDLTYNQGAGWHTGFPKFMAAFNKGDYEIAGDELKDSLWFNQVGRRGPTIVNLMKNKGLGDGIGQYLLDRGLVVPMDESKSSKGFDWTFGLAQFFGGAPAAAATLDSNINENRRDGMETNTKSDSYRVVPTSHADTGSGWGIEGVTDKFGRPLVFSQPAAQMFAKMMQASNGMVKGSDVASSGRSPSKNKEVDGHKNSVHLYGEGIDISGSSNAWMKNNASRFGWNYGYSHGPGSGHYDYEGEGAGKTPILGKAGSPSYSFMDLQKENAGRKLLASSSLSGLSLFGNNNDQPGSGRPFTDMFSEGTFGNMGDFFTTQGYQPNIFNSQNRTRFAQNNSEQIRVKKVTEQRNQARREINAKTSEIVQMALAAVEAQNGSNRQFISTAESAIRSLLGAQQGGGTFANVGGTTGTVLRTAVAVLNSFNNPLRGIFQ
Physico‐chemical
properties
protein length:933 AA
molecular weight:101415,6 Da
isoelectric point:9,39
hydropathy:-0,38
Representative Protein Details
Accession
3L6yL
Protein name
3L6yL
Sequence length
324 AA
Molecular weight
N/A Da
Isoelectric point
8,92631
Sequence
LEXXXXGGFLNGYAKGGWISGPQSGYPVSLDGNKPDFIGHGTEYVATKSDGSAFVVPFDTPATRAMPGLLSSRLAEASAMGFMSGGGELDHFAKRMIKENEGLRLKKYNDSLGNPTIGYGHLVKPDSKIPDTISKAYADQLFEKDYRYHKQAAQSIPGYDKMSLQQKAAMIDLTFNMGPQWYQDFPLMMAAIQRGDYKTAGAELKNSLYYTQVGRRGPVTVALIQNKGLVGVGEYLLNKGITIPKGSEAKKAGLFGGIFNVLLGASPAGASGLSDVEGFVEEGQRDKKGVLASNLGSLLIQPAGHSETGTGWGIKGAMDKHGRP
Other Proteins in cluster: phalp2_5188
Total (incl. this protein): 4 Avg length: 785,8 Avg pI: 9,34
Protein ID Length (AA) pI
3L6yL 324 8,92631
A0A345AW73 933 9,38507
E3SK58 953 9,66138
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_22830
2jJLb
 1 24,8% 221 1.886E-07

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Prochlorococcus phage P-RSM4
[NCBI] 		444862 Kyanoviridae > Thaumasvirus > Thaumasvirus stim4
Host Prochlorococcus marinus str. MIT 9303
[NCBI] 		59922 Cyanobacteria > Prochlorales > Prochlorococcaceae > Prochlorococcus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
GU071099 [NCBI]
CDS location
range 11904 -> 14705
strand +
CDS
ATGGCAACAGTAAAAAAAGGTGCGAAACTAGATTTTTATAAGTTTGTTGACCCTAATGCGGGAGCAAGCACTACTTCTAGAGCTAATGCAAAAGGAGGGAATAGAGAATTAACTACTGTTATAAAGCAAAATACAAGAGCAATTAATAGTATGGGTAGAGTTGTCAATTCTATTGGCAGCACTATAGTGTCTATAAAAGACGTGCAGATGAGGTTGTTGAAGATAGATGAAGAGAGATTAAAGAAAGCATCATTCGTACCCAAATATACGAAAAAACAACCTCCTCGTAAAATGAAAGCATTTGATAGTTTATTCAAGGGGAAAATACCAGGTTTCTTTGAATCACTTGCAAAATTAGCAAGTGCGTTGATAAAGTTTTTCTTAGTTCTTCCTGCTCTTAAATGGTTATCTAATCCTGAGAATCAAGATAAGGTTGTTAAAGGACTTGAAGTTCTTGCTAAAGTTTTTAAATTTATTGCATCTGTTGCTAAATTTGCCTTTGTTAATACTATAGAAGGACTGTACGATCTTTTAAAAGAAGATGCTACATGGATGGAAAGAATAGGTGGTTTTACGAGAGCACTTGCAGGATTGGGAACCGCATTCTTAGCATTAAATTTTCTTACAAATCCAATGGGGGTTATCAAAACCTTCTCAAGTGTGCTATTATTCTTTCACAAGGGTCTCCTTGCTGCCTTTGCCAAACTTGCTACCCATCCTTTGATTGCAGGTGCAGCACTGTTTCTTCTTCCAAAATATGCTGATCAAATTCCTGGTTTAGTCAATAAAAATGAGGAAGCGATTGCAGAGGGTTTAGAAACAACAACAAATGAATCTGGTGATACTATCATTGCAGAATCTGATGAAAAAGCACAAAGAATCGCAGATCTTAAAAAACAAAAAGAAGATCTTTCCCTTCTTGATAGGTTGTTTGGTAAAGGTAAAGAAATTGAAGAGTTAATTTATTACTTAGAAACTGGTAAAACTAAAAGTTATGGATTTTTTGAAAATGGAGGTTATCTAGATGGTTATGCTAAGGGTGGTTGGATTTCTGGTCCTCAGTCAGGGTATCCTGTATCACTAGATGGTAATAAACCTGATTTTATTGGACATGGAACTGAATATGTTGCACAGAAGTCGGATGGTGGTGCATTTATTGTTCCGTTTGATACTCCTGCAACTAAAAAGGATCCTGATCTAACATCTCGAAGAATGACTGAAGCAAGACTTCTAGGATTTTTTGAAGAAGGTGGTGGGTACGATAAGTTTGCTAAGAGAATGATTAAGATTCATGAGGGTTTCAGTCCAACAGCAATACCTGAACCTAATGGTGGAATGTCTATTGGATATGGTCATTATATTAAACCTTCTGATAATTTCCCTCCCACTATTAGTAGAGCGTTTGCAAATCAACTGTTCAAACAAGATTATAAAGATCATAAAAACGCTGCTATGAAAATACCTGGTTTCGGTAAATCTAGTCCTCAACAAAAAGCAGCATTGGTTGATCTAACCTATAATCAAGGTGCAGGTTGGCATACAGGATTCCCCAAGTTCATGGCAGCGTTCAACAAAGGTGATTATGAAATCGCAGGAGATGAACTAAAAGATAGTCTTTGGTTTAATCAAGTTGGACGTAGAGGACCTACTATTGTCAATTTGATGAAGAATAAAGGTTTGGGAGACGGTATTGGACAATACCTTTTAGATAGAGGTTTAGTAGTCCCTATGGACGAGTCGAAATCAAGTAAAGGATTTGATTGGACATTTGGATTAGCACAATTTTTTGGTGGAGCACCTGCTGCAGCTGCAACATTAGATTCTAATATCAATGAGAATAGACGTGATGGTATGGAGACTAATACTAAAAGTGATTCATATAGAGTCGTTCCTACTTCACATGCAGATACAGGTTCTGGATGGGGTATTGAGGGAGTTACCGATAAATTTGGTCGTCCTTTGGTATTCTCTCAACCTGCTGCTCAAATGTTTGCTAAGATGATGCAAGCATCAAATGGAATGGTAAAAGGATCTGATGTTGCAAGCAGTGGTAGATCACCATCAAAAAATAAAGAAGTTGACGGTCACAAAAACTCAGTTCATTTATATGGAGAAGGTATAGACATCTCTGGTTCTTCAAATGCATGGATGAAAAACAATGCTTCTAGATTTGGTTGGAATTATGGATACAGTCACGGACCTGGTAGTGGTCACTATGATTATGAGGGTGAAGGTGCAGGTAAGACTCCTATCTTAGGAAAAGCTGGATCTCCTTCATATTCGTTCATGGATTTACAGAAAGAAAACGCAGGAAGAAAATTACTTGCTTCAAGTAGTCTATCTGGATTAAGTTTATTTGGTAATAATAATGATCAACCAGGTTCTGGAAGACCTTTTACTGACATGTTCTCGGAGGGAACATTTGGTAATATGGGAGATTTCTTCACAACCCAAGGGTATCAACCAAACATATTTAATTCTCAGAATAGAACGAGGTTTGCACAAAATAATAGTGAACAAATCAGAGTTAAGAAAGTAACTGAACAAAGAAACCAAGCAAGAAGAGAAATCAATGCAAAGACTTCGGAGATTGTGCAGATGGCGTTGGCTGCTGTTGAAGCGCAAAATGGTTCCAATAGGCAATTCATTTCGACGGCTGAGTCGGCGATTAGGAGTTTATTAGGTGCTCAACAAGGTGGAGGTACGTTCGCTAATGTTGGTGGAACAACAGGAACAGTATTACGAACTGCTGTTGCTGTCTTAAATTCATTTAATAATCCTTTAAGAGGTATTTTCCAATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

PDB ID
upi0001e79e02_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (3L6yL) rather than this protein.
PDB ID
3L6yL
Method AlphaFoldv2
Resolution 75.41
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50