Protein

Protein accession
B1ABI2 [UniProt]
Representative
7uafd
Source
UniProt (cluster: phalp2_3976)
Protein name
Lysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 93% (predicted by ML model)
Protein sequence
MTINSSDVTAWINQNKGKYIDFDGWYGVQCYDLFNAYGKKFWNITFFGFNDPGDYWYHATLPNGWSRIANCKISDMHVGDIIMFGTANSVPYGHVGIVSGSGKMIDENGIGHGDPVTERNITDVIGWAPARYIGVVRPNIVGNGSGTQPLTPEQSFVKKLRELKYVDTSIFAIMGSIYGESGFDPTIIEGGGHMDFKTAVTSGWSGGWGLIQWTPPSKIKAYPEWDMLNRAEVQADVIDDFYNPARHKWSNDGAGASLSVIAQYQSSSGWANVDWNKVISYNFEYNKFIPDNASLETKLAYFIVCCERPNFSAALASYPKRLAAAQRYATQDWSHLGDYNDSNGNTSSDKNTRDSIKEAIDPDHLMLLMQFNNFL
Physico‐chemical
properties
protein length:375 AA
molecular weight:41838,2 Da
isoelectric point:5,26
hydropathy:-0,36
Representative Protein Details
Accession
7uafd
Protein name
7uafd
Sequence length
241 AA
Molecular weight
26526,11240 Da
Isoelectric point
4,83361
Sequence
MTTKSDVANWVTNNTGKYLDFDGAYGTQCFDLINFYVNDLFSKVGVIQAAGGAAKNIPDWLQSHLGWEKFYWSNESDLKYGDIITWNAYPGTTSPEFGHVAIYIGNSQKFETNGGTGSGYGSGDNATIRTLVTGGAYMAVRPPIIDDTDNPSNNTNKKGETTMQCTFTTGDGTIFYFNGYDKIIALNNLDQLTMINDLYLKNNGQAMPHYAWTPQAAWYKRLVEATGAKCVSTDGTPYGMY
Other Proteins in cluster: phalp2_3976
Total (incl. this protein): 2 Avg length: 308,0 Avg pI: 5,04
Protein ID Length (AA) pI
7uafd 241 4,83361
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_25333
7ocj2
 56 28,9% 197 1.465E-12
2 phalp2_12284
7duN8
 6 29,0% 234 3.934E-11
3 phalp2_19777
7Ns5Q
 32 26,9% 252 1.035E-09
4 phalp2_13805
70eSG
 253 27,1% 228 2.787E-07
5 phalp2_20473
3PSj2
 16 26,2% 206 1.201E-06
6 phalp2_35297
6Ynr2
 1 26,1% 264 2.151E-06
7 phalp2_9275
76k47
 345 26,9% 182 3.851E-06
8 phalp2_11511
Isow
 3 25,9% 181 1.231E-05
9 phalp2_37199
1X3cR
 12 29,1% 158 9.335E-05

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 7uafd (241 AA)
Member sequence: B1ABI2 (375 AA)
1 241 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactococcus phage asccphi28
[NCBI] 		503388 Salasmaviridae >
Host Lactococcus lactis
[NCBI] 		1358 Firmicutes > Bacilli > Lactobacillales > Streptococcaceae > Lactococcus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
EU438902 [NCBI]
CDS location
range 6563 -> 7690
strand +
CDS
ATGACAATTAATTCAAGTGATGTTACTGCATGGATTAACCAAAATAAAGGAAAATATATAGATTTTGACGGTTGGTATGGGGTTCAGTGTTATGACTTATTTAATGCTTATGGCAAAAAGTTTTGGAATATCACTTTTTTTGGATTTAATGACCCCGGGGATTATTGGTATCATGCAACGCTTCCGAATGGGTGGAGTAGAATCGCTAACTGTAAAATATCAGATATGCACGTAGGCGATATCATTATGTTTGGGACAGCCAATTCTGTACCCTATGGACATGTGGGTATCGTTTCGGGTTCAGGTAAAATGATAGACGAAAATGGGATAGGACACGGCGACCCTGTGACCGAACGCAATATAACTGATGTTATCGGTTGGGCTCCCGCAAGATATATCGGAGTTGTCCGTCCGAATATTGTGGGAAATGGTTCAGGCACGCAACCCTTAACCCCCGAACAATCGTTTGTTAAAAAGCTAAGAGAATTAAAATATGTAGATACTTCTATTTTTGCAATCATGGGGAGTATTTACGGAGAAAGTGGTTTTGACCCGACAATAATTGAGGGAGGCGGTCACATGGATTTTAAAACAGCTGTCACATCAGGCTGGTCTGGTGGTTGGGGGTTGATTCAATGGACGCCACCTTCTAAAATAAAAGCTTATCCTGAATGGGACATGCTCAATCGAGCAGAAGTACAAGCGGACGTCATAGACGATTTTTATAATCCTGCACGACATAAATGGTCTAATGACGGGGCGGGCGCTTCACTTTCTGTTATTGCGCAATATCAAAGCTCAAGTGGTTGGGCAAATGTCGATTGGAATAAAGTCATTTCATACAACTTTGAATATAATAAGTTTATTCCTGATAACGCAAGCTTAGAGACAAAACTCGCCTATTTTATTGTTTGTTGCGAACGTCCTAATTTTAGTGCTGCCTTAGCCTCATACCCTAAACGGTTAGCAGCCGCCCAAAGATACGCAACGCAAGATTGGTCACATTTAGGGGATTATAATGACTCGAATGGGAATACAAGTAGTGATAAAAATACAAGAGATAGTATTAAAGAGGCAATAGACCCCGACCATTTAATGCTCCTTATGCAATTCAACAACTTTCTATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000165f867_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7uafd) rather than this protein.
PDB ID
7uafd
Method AlphaFoldv2
Resolution 83.24
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50