Protein

Protein accession
A7XXT9 [UniProt]
Representative
7QoNY
Source
UniProt (cluster: phalp2_15995)
Protein name
Peptidoglycan hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MHGQTNHEGIPHPGYDLNFGPTPDADYGQAVYAPEDGKVVFAKQGLGTWGGLVVVLGASGYAHRLGHVERMTVKEGQRVKEGDQVAVIGRVQGMAPHLHYDMVRPEVIKTITILLKAPYERWDFWHVNFPKLFDVMYLDPAKFHPELARLLSK
Physico‐chemical
properties
protein length:153 AA
molecular weight:17142,5 Da
isoelectric point:6,75
hydropathy:-0,28
Representative Protein Details
Accession
7QoNY
Protein name
7QoNY
Sequence length
165 AA
Molecular weight
18549,10400 Da
Isoelectric point
8,78119
Sequence
MRLPTKTSRFGYVHGQTNHEGIPHPGYDLNFGPTPDADYGQAVYAPEDGKVVFAKQGLGTWGGLVVVLGASGYAHRLGHVERMTVKEGQRVKEGDQVAVIGRVQGMAPHLHYDMVRPEVIKTITILLKAPYERWDFWHVNFPKLFDVMYLDPAKFHPELARLLSK
Other Proteins in cluster: phalp2_15995
Total (incl. this protein): 18 Avg length: 181,9 Avg pI: 8,85
Protein ID Length (AA) pI
7QoNY 165 8,78119
2NqNx 197 9,32775
3sF9 196 9,07478
45LPg 197 9,50382
5DlsL 171 9,51297
7AZIV 196 8,56819
7QoMf 165 8,01299
7cXeM 209 9,21564
7o0Y2 196 9,24008
7vXL9 196 9,07471
84rW5 216 10,68630
8J9qg 166 8,01305
8evxA 189 9,29694
8jGo4 166 9,07252
A7XXE4 165 8,01299
A0A1L4BKS4 166 8,01305
A0A411CWC0 166 9,12584
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_21326
1KVjU
 4 33,5% 140 8.421E-24
2 phalp2_25763
4QogS
 4 33,3% 141 6.072E-21
3 phalp2_32931
3R3GB
 42 24,5% 167 6.072E-21
4 phalp2_1625
8dQyh
 5 28,4% 116 3.198E-13
5 phalp2_35838
4GGll
 4 31,2% 131 3.198E-13
6 phalp2_30262
4ib6k
 5 30,8% 107 3.820E-12
7 phalp2_27996
15l2O
 11 36,7% 117 5.207E-12
8 phalp2_34915
4pbkX
 159 29,9% 127 4.539E-11
9 phalp2_27905
l4Bb
 39 27,3% 117 1.146E-10
10 phalp2_18623
3ebV
 83 32,7% 110 2.125E-10

Domains

Domains [InterPro]
PET_M23
Representative sequence (used for alignment): 7QoNY (165 AA)
Member sequence: A7XXT9 (153 AA)
1 165 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Thermus virus P74-26 (Thermus thermophilus phage P74-26)
[NCBI] 		466052 Oshimavirus >
Host Thermus thermophilus
[NCBI] 		274 Deinococcus-Thermus > Deinococci > Thermales > Thermaceae > Thermus >

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
EU100884 [NCBI]
CDS location
range 78904 -> 79365
strand +
CDS
GTGCACGGCCAGACCAACCACGAAGGTATTCCCCATCCAGGTTATGACCTAAACTTTGGCCCTACACCTGATGCCGACTATGGGCAAGCCGTGTACGCCCCCGAAGACGGCAAGGTGGTATTCGCCAAACAAGGCTTAGGCACTTGGGGCGGGCTAGTGGTGGTGCTAGGAGCATCGGGCTACGCCCACCGCCTAGGTCATGTAGAGCGCATGACGGTAAAGGAAGGCCAACGGGTCAAAGAGGGCGACCAGGTGGCGGTGATTGGCCGCGTGCAGGGCATGGCACCGCACCTGCACTACGACATGGTCAGGCCGGAGGTCATCAAGACCATCACCATACTGCTCAAGGCGCCCTACGAGCGTTGGGACTTCTGGCACGTGAACTTCCCAAAGCTTTTTGACGTGATGTACCTGGACCCGGCCAAGTTCCACCCGGAGCTAGCCAGGCTTCTAAGCAAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi00015c337f_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7QoNY) rather than this protein.
PDB ID
7QoNY
Method AlphaFoldv2
Resolution 89.25
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50