Protein

Protein accession
A5GZ20 [UniProt]
Representative
7stqi
Source
UniProt (cluster: phalp2_8224)
Protein name
Putative endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSSIENMIAWMQARKGRVTYSMTSRMGPRSYDCSSSVFFAMIAGGFLSAGSMGNTETLFGMSGTKLKEISRGEVQRGDIFISGTPGGSAGSDGHTGIFLSNGSFIHCSYTHNGIAVDTNDAYMSTRLPHHFYRIVGSGLANTDSKPQMVTLNVDGQFGNATAKRLQEYFDTAGKDGVISHQYKQTFNQNIYAAQFDSSLTGSNVVKALQRFLGIGQDGLFGQGTIKALQKHLGTTQDGTISPVSDSVRELQRRLNANKL
Physico‐chemical
properties
protein length:259 AA
molecular weight:27955,1 Da
isoelectric point:9,23
hydropathy:-0,31
Representative Protein Details
Accession
7stqi
Protein name
7stqi
Sequence length
355 AA
Molecular weight
38522,17320 Da
Isoelectric point
8,89897
Sequence
MKTIDKGTLTRTILLWLAILNQVLTALGKNPLPLDDNTVSTLITAVFALLAWWKNNDFTHAAKKGTELTKSLKNGDSVQVVKASDADHEFTEGGRMMSSIENMIAWMQARKGKVTYSMTSRMGPTSYDCSSSVFFAMIAGGFLSVGSMGNTETLFGMSGTKLKEISRGEVQRGDIFISGTPGGSAGSDGHTGIFLSNGSFIHCSYTHNGIAIDTNDAYMSTRLPHHFYRIVGSGSANTDDKPQMVTLNLDGQFGNATAKRLQEYFDTAGKDGVISHQYKQTFNQNIYAAQFDSSLTGSNVVKALQRFLGIGQDGLFGQATIKALQKHLGTTQDGIISPVSDFVRELQRRLNANKL
Other Proteins in cluster: phalp2_8224
Total (incl. this protein): 171 Avg length: 263,9 Avg pI: 9,04
Protein ID Length (AA) pI
7stqi 355 8,89897
13qGC 263 9,31705
13qRk 316 9,41936
1bImr 319 9,43993
1bLeL 271 9,36482
1bVwE 260 8,98427
1c0Nh 263 9,20913
1c93e 259 9,55913
1c9fV 196 9,20507
1cbxj 316 9,55842
1ceDt 316 9,09696
1cjIc 267 8,56045
1deUR 263 9,47848
1jLfR 259 9,03642
1jOdL 259 9,20443
1jPf2 259 9,11378
1jQbt 259 8,94210
1mHiz 259 9,22557
1mLrB 260 8,83180
1n4KF 260 9,31705
1nSqp 259 9,33710
1o2le 259 8,86668
2Vw8e 259 9,03642
2jYkS 260 9,39403
3MAdD 316 9,17890
3MLK4 263 9,41182
3MOTf 260 8,81562
3uGbM 261 9,59684
4ET7J 273 9,37282
4ET8H 316 9,07568
4EZy3 259 9,03642
4Eklj 259 7,05397
4F0iy 263 9,41208
5Gzxf 325 9,22686
5Sco4 259 8,83180
5TcDe 258 9,18431
5hRnX 316 9,43993
5i2hX 263 9,41201
5i3VR 300 9,38674
5i50J 263 9,33478
5ip3p 316 8,91767
5tQE2 259 9,18444
63PkB 259 9,32040
67beI 259 9,03642
6BACy 246 7,12229
6BzgY 326 8,50462
6Ezrl 243 7,75707
6Qe4q 242 7,75707
6SHFQ 316 8,99058
6lhKQ 259 9,20417
6mKVr 263 9,30010
6nVfU 258 9,23730
6oM8m 318 9,17902
6oqVO 267 9,15233
6sMrU 259 9,20443
6taL2 263 9,30010
71EV7 259 8,46691
72l2q 260 9,41201
74AYT 316 9,01444
75TMM 259 9,20443
75kAT 259 9,18444
76k5r 263 9,53154
78hry 259 9,18444
78hsG 259 9,07491
79Iuz 259 8,48090
79IyW 259 9,29939
7C3mJ 259 9,34213
7PP7a 259 9,03642
7QDkU 259 9,20449
7QDpq 259 9,18418
7QDrc 259 9,20443
7QGhJ 259 9,16523
7VqO2 316 8,98046
7WDmv 259 9,18418
7YyAQ 259 8,81562
7b8kT 267 8,98207
7bjfu 259 9,18444
7cJH1 259 9,03642
7cJHc 259 7,80159
7cNeW 258 9,13196
7cOgx 259 9,21854
7dcVE 259 8,84901
7dmll 253 9,32040
7dmmp 259 8,81562
7eOfc 259 9,03623
7ezHT 260 8,48231
7ezIs 259 9,03642
7fDeT 259 8,49385
7fte8 259 8,80008
7gXFC 259 9,18444
7gXFh 259 6,58556
7iceL 259 9,29939
7ig29 259 7,82100
7iihk 260 9,03642
7lDTH 316 8,97060
7lIQp 259 9,03623
7mvAk 260 8,95390
7mvzi 260 8,98427
7sD7A 259 9,03642
7sSLO 259 9,18444
7sSQN 259 9,03623
7sSRG 259 8,49373
7sSrP 259 7,12684
7sSxD 259 9,03642
7sSy8 259 8,48225
7t3oi 249 9,43683
7tM8E 259 9,03623
7tXSx 259 9,18444
7taRq 259 9,05525
7taSG 259 9,18444
7tb5G 259 9,27966
7uG2b 259 9,31789
7uU6I 259 9,05525
7uUl2 259 9,20443
7usMT 259 7,78812
7usRk 259 9,36540
7v8sF 259 9,20443
7vZqx 239 9,40157
7vkR0 259 8,81562
7vkYs 259 8,83180
7wXKd 259 9,39274
7xeiD 259 9,05525
7z9KH 259 9,20443
7zHDH 249 9,16510
886Kx 279 9,28508
8IEwA 253 9,43683
8IEwB 259 9,16542
8IEwF 259 9,22557
8IEwI 259 9,27966
8IEwJ 259 9,03642
8IEwM 259 9,22531
8IEwN 259 9,18450
8IEwQ 259 8,84882
8IEwS 259 9,03642
8IEwT 259 9,23685
8IEwU 259 9,16542
8LNBb 259 9,05505
8Momt 259 9,03642
8fhbL 259 9,18444
8ob16 267 9,21893
8omQQ 271 9,47332
DSah 259 9,16542
A0A1P8BMN4 112 9,39590
A0A649V176 259 9,16523
Q9AZW7 259 9,03642
A0A1B1IN46 253 9,43683
A0A1P8BM38 259 9,16542
A5GYY0 259 9,22557
A0A1P8BLX0 259 9,27966
Q38323 259 9,03642
A0A1P8BMG9 259 9,22531
A0A1P8BM94 259 9,18450
A0A1P8BKD1 259 8,84882
A0A1P8BKR7 259 9,03642
A0A1P8BMC3 259 9,23685
A0A1P8BKK1 259 9,16542
R9QNI8 259 9,05505
A0A1B1IMF2 259 9,03642
A0A1B1IM47 259 9,03642
A0A1B1IMJ5 253 9,43683
A0A1B1IMR2 259 9,03642
A0A1P8BLQ4 259 9,16542
A0A649V126 259 9,16523
A5GYT2 259 9,22557
Q9AZK9 259 9,16523
A0A977KEM5 259 9,22557
A0AA48S0K6 258 9,23698
A0AAE7S344 259 9,03642
Q9AZR1 259 9,20443
Q9FZS9 259 8,83180
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_16344
5tY8v
 2 88,4% 225 3.603E-117
2 phalp2_24701
6a9a2
 161 31,2% 285 5.946E-26
3 phalp2_6346
7lBVC
 7 27,5% 287 3.499E-13
4 phalp2_18014
3fSwu
 12 25,4% 279 6.217E-13

Domains

Domains [InterPro]
Disordered region
Ami5
Unannotated
Representative sequence (used for alignment): 7stqi (355 AA)
Member sequence: A5GZ20 (259 AA)
1 355 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05382

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactococcus phage phismq86
[NCBI] 		444474 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
DQ394810 [NCBI]
CDS location
range 31808 -> 32587
strand +
CDS
ATGTCAAGTATTGAAAATATGATTGCTTGGATGCAGGCACGAAAAGGCAGAGTAACTTACTCAATGACTTCACGAATGGGTCCTAGAAGTTATGACTGCAGCTCGTCAGTATTCTTTGCAATGATTGCTGGTGGTTTTCTGTCAGCAGGTTCAATGGGAAATACTGAAACCTTGTTTGGAATGTCAGGAACAAAACTGAAAGAAATTAGTCGAGGAGAAGTGCAACGTGGCGATATTTTCATTTCAGGCACTCCAGGAGGTTCGGCTGGCTCTGACGGACACACCGGTATCTTCCTAAGCAATGGCTCATTCATTCACTGCTCTTACACTCACAATGGAATTGCGGTTGATACGAATGATGCTTATATGAGTACAAGATTGCCACATCACTTTTACAGAATTGTTGGTTCAGGTTTAGCAAATACTGACAGTAAGCCTCAAATGGTTACATTAAATGTCGATGGTCAATTTGGAAATGCGACCGCTAAACGATTGCAAGAATATTTTGATACAGCTGGTAAAGATGGAGTAATCAGTCACCAGTACAAACAAACCTTTAACCAAAATATTTATGCTGCTCAGTTTGATTCATCGCTGACAGGTTCAAACGTGGTTAAAGCATTGCAAAGATTCTTAGGCATTGGCCAAGACGGACTGTTTGGCCAAGGTACAATTAAAGCACTACAAAAACATCTTGGAACGACGCAAGACGGAACTATCAGCCCAGTTTCTGATTCTGTGAGAGAATTACAACGTCGATTGAATGCGAATAAACTGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000150d6a1_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7stqi) rather than this protein.
PDB ID
7stqi
Method AlphaFoldv2
Resolution 79.92
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50