Protein

Protein accession
A0A8F4TCS4 [UniProt]
Representative
jqQ5
Source
UniProt (cluster: phalp2_30848)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MRENFLRKVVKEEYSEFLEQIKTFIKLWENRESPVSGIIDLSHWQENVDFELAKENGIVGVIHKATQGTEYIDSKYKERRKEAKDLSLLWGSYHFGVGEDGRDQANHFLNTVGETKNTIVVLDIEENESGKNIEPKQAEDFVKKIQEETGRLPLVYGGANFLKDFATPILTKCPLWIARYGDQPVLPQGWNKWILWQYTDGKNGPEPHEVSGIGKCDRNKFNGTLKELREFWLV
Physico‐chemical
properties
protein length:234 AA
molecular weight:27089,3 Da
isoelectric point:5,54
hydropathy:-0,66
Representative Protein Details
Accession
jqQ5
Protein name
jqQ5
Sequence length
467 AA
Molecular weight
51384,49710 Da
Isoelectric point
4,63155
Sequence
MTEIFPHVVDLSHHNTDDGSEIDWGAAKRDGIWGVIYKATESDDYVDPTYDESRRQAKAVGLLWGAYHFFRPGNVQRQVDHFLENAMPGPDTLLVLDHEDEGCSVQDVKEFLRLVEQQTGQRPALYSGNVIKEQLGNRIDSYLAGTRLWLAQYGSEAEAPATWPRGPWLWQFTDGNVGPSPHSINGIGRCDINSYEGTPQQLQQTWAQAGVAPPSPPDPPTPPPDPGVPAWLTAMRSITGMTEAPGSADNPKIIGMARYVGDKWPEQKSYSDQYTADATAWCGVTVAYCVSVADIKPVFGPTDTDKWMWAESWSRWPNSVHLDEPRLGCIVVFRWDSGSHHVTLYESTEGSNYKCRGGNQSDMVNVASFPAANAIALVWPGTQAPPPRPTLKLSAIDLMWVQASLNLVDAAGLDVDGEYGPMTHGAITSYQRDNDLPVTGYASKETVDELISEVMAWNQARPEPGEA
Other Proteins in cluster: phalp2_30848
Total (incl. this protein): 8 Avg length: 418,1 Avg pI: 4,80
Protein ID Length (AA) pI
jqQ5 467 4,63155
2YTfa 482 4,70805
6IbE5 528 4,50934
6Ifjo 543 4,69589
6QAOP 390 4,51736
jGGN 470 4,75000
A0A6B9SX07 231 5,04681
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_35982
5nNrs
 19 26,9% 342 7.239E-25

Domains

Domains [InterPro]
GH25
Unannotated
PG_1
Representative sequence (used for alignment): jqQ5 (467 AA)
Member sequence: A0A8F4TCS4 (234 AA)
1 467 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Wolbachia phage WO
[NCBI] 		112596 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MW788653 [NCBI]
CDS location
range 1941 -> 2645
strand +
CDS
ATGAGGGAGAATTTTCTGAGAAAAGTTGTAAAAGAGGAATATTCTGAATTTTTAGAGCAAATAAAAACTTTCATAAAACTATGGGAGAATAGAGAGAGTCCAGTAAGTGGAATAATAGATTTGTCACATTGGCAAGAAAATGTGGATTTTGAGTTAGCTAAAGAGAATGGTATAGTTGGAGTAATTCACAAGGCAACGCAAGGAACAGAGTACATAGATTCAAAATACAAAGAAAGAAGAAAAGAAGCCAAAGACTTGAGTCTATTATGGGGTTCATATCATTTCGGTGTAGGAGAAGATGGAAGAGATCAGGCAAATCACTTTTTGAATACAGTGGGTGAAACTAAAAATACAATTGTTGTGCTTGATATTGAAGAGAACGAAAGTGGAAAAAATATAGAACCAAAACAAGCAGAAGATTTTGTTAAAAAAATTCAAGAAGAAACAGGGCGTTTACCTTTAGTGTATGGAGGTGCTAATTTTTTGAAAGATTTTGCCACACCAATTTTGACGAAATGTCCATTATGGATAGCAAGATATGGAGATCAACCTGTTTTACCGCAAGGATGGAATAAGTGGATTTTATGGCAATACACCGACGGTAAAAATGGTCCAGAGCCACATGAAGTAAGTGGAATCGGAAAATGTGACAGAAATAAATTTAACGGAACTTTGAAAGAATTAAGAGAATTTTGGTTAGTATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (jqQ5) rather than this protein.
PDB ID
jqQ5
Method AlphaFoldv2
Resolution 88.40
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50