Protein

Protein accession
A0A7U0G803 [UniProt]
Representative
8tcB0
Source
UniProt (cluster: phalp2_13095)
Protein name
Lysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRTLDEGIKWINNSVGKQYDFDNAYGYQCYDYANSYFNYMTGYRLSGMYAKNIHTDNAKLLSNIATVYENTPNFLPLPGDIVIFNGRYGSGAGHVAVVTKATLNSFEVVEQNWEGGGFVNGRPGWESATRRWHYYDNPMWFIRLNYATKKSITNLLPSKTPKPTKLKVALVPGHGYADPGAVGNGTNERDFIRKNIVPNVAKYLRSAGHDVYLYGGSKMTQDMYQDTAYGQRLGNKKDYGFYWLKRNQKPDIVVEFHLDAAGASASGGHVIISNQFNADTIDNGIQSVIKSNLGQIRGVTPRNDLLNVNVSAELNVNYRLVELGFITNASDMNYIKNNTDKYCRDIAGAIHGKPVGGTLAGKTQIKRTSWYLKGIFYPDRTIKVRRQPGLKGEEVDQGSWLYNKNNWVEFDQVIKKDKYWWIRFKYQAPGSSKSYFYCAVCPITDKNEVMKNEKFWGSIKWK
Physico‐chemical
properties
protein length:462 AA
molecular weight:52462,7 Da
isoelectric point:9,40
hydropathy:-0,57
Representative Protein Details
Accession
8tcB0
Protein name
8tcB0
Sequence length
160 AA
Molecular weight
18843,53810 Da
Isoelectric point
9,84537
Sequence
MTPRNDLLNVNVSAELNVNYRLAELGFITNKNDMDYIKKNADKYCRDIAGAIHGKPYWRYLAGKSQVNRISWSWKGIFYPDRAIKVRRQPGLKGEEVDKGSWLYNKNDWVKFDQVIKKDKYWWIRFKYQAPGSSKSYFYCAVALLLTKQKKSKMRSIGEV
Other Proteins in cluster: phalp2_13095
Total (incl. this protein): 3 Avg length: 361,3 Avg pI: 9,58
Protein ID Length (AA) pI
8tcB0 160 9,84537
A0A7D7F7D7 462 9,48009
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_4322
8ftop
 34 57,5% 153 7.718E-54

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 8tcB0 (160 AA)
Member sequence: A0A7U0G803 (462 AA)
1 160 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Staphylococcus phage PMBT9
[NCBI] 		2796498 Rockefellervirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MW221967 [NCBI]
CDS location
range 23726 -> 25114
strand +
CDS
ATGAGAACACTTGATGAGGGTATAAAATGGATTAACAACTCTGTAGGTAAGCAATACGACTTCGATAATGCATATGGATACCAATGTTACGACTACGCTAACAGTTACTTCAATTATATGACTGGTTACAGATTAAGTGGAATGTACGCTAAAAATATACACACTGATAATGCAAAATTATTAAGTAATATAGCTACAGTATACGAAAACACACCTAACTTTTTACCATTACCAGGCGACATAGTTATATTTAATGGACGCTACGGAAGTGGCGCGGGGCATGTTGCGGTAGTAACTAAAGCGACTTTAAATAGCTTTGAGGTAGTCGAACAGAACTGGGAAGGTGGCGGGTTTGTAAATGGTCGTCCTGGTTGGGAATCCGCTACACGCCGTTGGCATTATTACGATAATCCGATGTGGTTTATTCGCTTAAATTACGCGACTAAGAAGTCGATCACTAACCTTTTACCTAGCAAGACGCCTAAACCGACTAAACTTAAAGTGGCGCTTGTGCCAGGGCATGGATACGCAGACCCGGGAGCGGTTGGTAACGGTACAAATGAACGTGACTTTATCCGTAAGAATATTGTGCCTAACGTGGCTAAATACTTACGTAGTGCAGGGCATGACGTGTATTTATATGGCGGTTCAAAAATGACACAAGACATGTACCAAGACACGGCATATGGTCAACGTCTAGGTAACAAAAAGGATTACGGGTTCTACTGGCTCAAACGTAATCAAAAGCCCGATATTGTTGTTGAATTCCACTTAGATGCAGCAGGTGCTAGCGCTAGTGGAGGTCATGTAATCATTTCAAACCAATTTAATGCCGACACAATAGATAATGGAATACAATCTGTTATTAAGTCTAATTTAGGTCAAATTCGAGGTGTGACGCCACGTAATGACTTGTTGAATGTCAATGTATCGGCAGAACTTAACGTCAATTACAGACTGGTAGAATTAGGTTTTATCACTAACGCATCAGACATGAATTACATCAAGAATAATACTGATAAATACTGTCGTGATATTGCAGGTGCAATTCACGGTAAACCCGTTGGTGGTACATTAGCTGGTAAGACACAAATAAAAAGAACGTCATGGTATTTAAAAGGTATATTCTACCCTGACCGCACTATTAAGGTACGTCGTCAACCAGGACTTAAAGGCGAAGAGGTAGACCAAGGCTCATGGCTATACAATAAAAATAATTGGGTTGAATTTGATCAAGTCATAAAAAAAGACAAGTATTGGTGGATTAGATTCAAGTACCAAGCACCAGGTTCAAGCAAATCATACTTTTATTGCGCTGTGTGTCCAATCACAGATAAAAATGAAGTGATGAAAAACGAAAAGTTCTGGGGCTCTATCAAATGGAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8tcB0) rather than this protein.
PDB ID
8tcB0
Method AlphaFoldv2
Resolution 84.59
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50