Protein

Protein accession
A0A7T6ZLZ2 [UniProt]
Representative
285Oe
Source
UniProt (cluster: phalp2_5171)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MANFKKRLSTDHIVIHCSATRPSMDVGVRQIRQWHLAQGWLDVGYHFIIKRDGTVEEGRPIDAVGSGVKNHNHNTVHICLVGGVPEDNPNGFEANFTDAQNESLKELVAKCQKYYSRADVIGHHDLDSGKACPSFSVSHWLDTGEFITASKG
Physico‐chemical
properties
protein length:152 AA
molecular weight:16838,7 Da
isoelectric point:6,53
hydropathy:-0,44
Representative Protein Details
Accession
285Oe
Protein name
285Oe
Sequence length
212 AA
Molecular weight
23415,88220 Da
Isoelectric point
9,06440
Sequence
VRTATSYICVHCSASPAKMDIGIKEITEWHRERGFFTIGYHYVIRRDGTRERGRPLNEIGAHVVGHNHHSVGVCLVGGVSGDGTLTPEDNFTSEQWTTLYLTLKELHEAYPKAVIVGHRDLDAGKACPSFDVSPIRCAEQQDYALASKWRSGRSALMRRERRRSSRLNTRRSDHGSTIPTSNCPTESSSSARAGSGQPIGRSICVSSFNDQS
Other Proteins in cluster: phalp2_5171
Total (incl. this protein): 13 Avg length: 157,5 Avg pI: 8,52
Protein ID Length (AA) pI
285Oe 212 9,06440
A0A385IFJ8 155 9,37540
A0A385IGH5 155 9,24330
A0A385IFR3 155 9,21829
E5RV07 156 9,14434
A0A0U1ZH11 181 8,90729
A0A385IGT7 155 9,21829
A0A6G5Y6J6 152 6,53423
A0A873WRN5 152 7,14747
A0A9Y1HTY5 156 8,79292
A0AAE9VNM7 156 8,45917
A0AAF0GQC8 111 9,09741
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11894
2jrH4
 329 58,3% 137 7.870E-54
2 phalp2_12381
8yxE3
 11 54,8% 133 3.790E-53
3 phalp2_2237
4n15b
 512 53,0% 147 6.453E-49
4 phalp2_36193
72BPm
 409 57,5% 132 8.849E-46
5 phalp2_23565
7vNZv
 154 40,8% 137 2.410E-34
6 phalp2_12261
71VXz
 7 45,2% 148 2.410E-34
7 phalp2_24952
kjdf
 441 41,0% 156 3.880E-30
8 phalp2_31037
1Au9U
 14 39,1% 143 1.063E-27
9 phalp2_19329
8knGF
 9 33,1% 145 9.211E-22
10 phalp2_26402
1DZug
 12 36,1% 130 2.770E-20

Domains

Domains [InterPro]
Ami2
Disordered region
Representative sequence (used for alignment): 285Oe (212 AA)
Member sequence: A0A7T6ZLZ2 (152 AA)
1 212 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Providencia phage PSTRCR_120
[NCBI] 		2800826 Autographiviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MW358928 [NCBI]
CDS location
range 36940 -> 37398
strand -
CDS
GTGGCGAACTTTAAGAAACGTTTATCAACTGACCATATTGTTATTCATTGTAGTGCAACTAGACCAAGTATGGATGTAGGTGTACGTCAGATTCGCCAATGGCATTTAGCTCAAGGCTGGTTGGACGTTGGATATCACTTTATCATCAAACGTGATGGAACGGTTGAAGAAGGTCGACCAATTGATGCTGTAGGTTCAGGCGTTAAGAACCACAATCATAACACTGTACACATTTGTCTAGTAGGTGGAGTACCAGAAGATAATCCAAATGGATTCGAGGCTAACTTTACAGATGCTCAGAATGAGTCACTAAAGGAACTTGTAGCTAAGTGCCAGAAGTATTACTCACGAGCAGACGTTATTGGTCATCATGACTTGGACTCAGGTAAAGCTTGTCCTTCATTTAGTGTTAGCCATTGGTTAGACACTGGTGAGTTTATTACAGCATCAAAGGGGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (285Oe) rather than this protein.
PDB ID
285Oe
Method AlphaFoldv2
Resolution 84.21
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50