Protein

Protein accession
A0A7S5WS12 [UniProt]
Representative
4LryU
Source
UniProt (cluster: phalp2_35865)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRPVDVKYPVSQGFGSGATQGVDPYGDDPMAELVRLYGNYQPFGHAGMDIACPVGTPVYAMSSGLVLWADWGTNLPGDDSGAGWASRWYLYKGFPGIVTVIQHPWGIGVYAHLSSNDAAPAGTVVKEGQLIGYSGNTGGVAPHLHVEALINLSYVTAGALIYGRTDPAPFFGRLTPQSTGTTAQAKGFLMALSDKQQTDLYNRIIRYVDSPVSAVPKKVWGITILRGGKKVSALQELADAKTLIQKQQATIDALTAVVKAQQAPVQAVTK
Physico‐chemical
properties
protein length:270 AA
molecular weight:28635,3 Da
isoelectric point:8,50
hydropathy:-0,03
Representative Protein Details
Accession
4LryU
Protein name
4LryU
Sequence length
326 AA
Molecular weight
34862,61310 Da
Isoelectric point
6,79359
Sequence
MRPVSAKFPVSQPFGGGATQGVDPYGNDPMAELVRQYGNYQPYGHAGEDIACPVGTPVYAAAPGTVLWADWGTNLPGDDSDWGYRQRWYLYKGFPGIVTVIQHPGWIGVYAHLSNNDPAPAGTVVKEGQLIAYSGNTGGVAPHLHREALVDLNYTTGGGLIYGRTNPAKYDGVTLRPESSTVKAAPAASTTKESEMPVTKRVDSTFKARHRLPKGSAYTLSVKDDGTSANFAVNGVGHYVIHNYIRGEGLLPGQRIKAQFFLVKSGKASGHFEQDIVGTIDGTFDHPVVLNRTIEAGTLVTCLLTSSNTETAYITGFGAEVTTWKA
Other Proteins in cluster: phalp2_35865
Total (incl. this protein): 8 Avg length: 299,1 Avg pI: 6,86
Protein ID Length (AA) pI
4LryU 326 6,79359
4MRqW 329 6,70083
7zTJH 331 6,86589
A0A649VNF3 205 4,82543
A0A5J6TGU3 331 6,86589
A0A3G3M3C4 275 7,73911
A0A8F3E612 326 6,54782
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_276
6CCkj
 17 55,1% 203 1.640E-68
2 phalp2_21748
3Ptm0
 18 35,2% 335 1.084E-54
3 phalp2_33817
1joRs
 29 39,6% 232 4.409E-39
4 phalp2_14600
5kHaZ
 35 32,1% 202 2.759E-22
5 phalp2_8917
3eyO9
 2 33,3% 252 6.419E-19

Domains

Domains [InterPro]
PET_M23
Unannotated
Representative sequence (used for alignment): 4LryU (326 AA)
Member sequence: A0A7S5WS12 (270 AA)
1 326 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Arthrobacter phage Jinkies
[NCBI] 		2743903 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MT498043 [NCBI]
CDS location
range 23927 -> 24739
strand +
CDS
ATGAGACCTGTTGACGTGAAGTACCCCGTTTCGCAGGGGTTCGGCTCGGGCGCGACGCAGGGCGTTGACCCCTACGGCGACGACCCTATGGCCGAACTCGTCCGCCTGTACGGGAATTACCAGCCGTTCGGGCATGCGGGCATGGATATCGCCTGCCCGGTCGGCACGCCCGTCTATGCCATGTCATCCGGGCTGGTGTTGTGGGCGGACTGGGGCACGAACCTGCCCGGCGACGACTCAGGCGCCGGCTGGGCGTCCCGCTGGTACTTGTACAAGGGGTTCCCCGGGATCGTGACCGTCATACAGCACCCGTGGGGCATCGGCGTCTACGCGCACCTGTCCAGCAACGACGCGGCCCCTGCCGGGACGGTCGTCAAAGAGGGGCAACTGATCGGCTACTCCGGTAACACCGGGGGCGTCGCCCCGCACCTGCACGTCGAAGCGCTGATCAACCTCTCCTACGTGACCGCGGGCGCCTTGATATACGGCCGCACCGACCCGGCCCCGTTCTTCGGACGCCTCACCCCCCAATCAACCGGCACGACCGCCCAAGCGAAAGGTTTCCTTATGGCACTCTCGGATAAGCAACAGACCGACCTTTATAACCGGATCATCCGTTACGTCGATTCCCCGGTCTCGGCCGTCCCGAAGAAGGTGTGGGGGATCACCATCCTGCGCGGCGGGAAGAAGGTCAGTGCCCTGCAGGAACTCGCCGACGCGAAGACCCTGATCCAGAAGCAGCAGGCCACGATCGACGCGCTGACCGCCGTCGTGAAGGCGCAGCAGGCCCCCGTTCAGGCGGTGACGAAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4LryU) rather than this protein.
PDB ID
4LryU
Method AlphaFoldv2
Resolution 85.17
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50