Protein

Protein accession
A0A7S5USA3 [UniProt]
Representative
3bvr0
Source
UniProt (cluster: phalp2_24269)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MPINKILPSKRAAVAIASIISLSAGGYVTMSSGYKVHDDVALASTYLIGPWEGRELVAYLDKLAKPPVVTICDGDTTNVKLGMRETPAGCDKRLQSKMETVYRPALVKCVIDFDKHPVAWRAMADSIAWNIGTGAACNSTAIRIVNDAMRKKTVPDYVASCKAATAFNKAGGKVYIGLVNRREMGDKTRIGEAEMCVTGAQ
Physico‐chemical
properties
protein length:201 AA
molecular weight:21584,9 Da
isoelectric point:9,22
hydropathy:-0,02
Representative Protein Details
Accession
3bvr0
Protein name
3bvr0
Sequence length
78 AA
Molecular weight
8953,18940 Da
Isoelectric point
8,70879
Sequence
MRVLLPLVAKWEGKKNTAYLDTIASPAVWTVCYGETRGVKRGDTYTDAQCSAMLERGLVQFRDGLHEFFTRETRDLRL
Other Proteins in cluster: phalp2_24269
Total (incl. this protein): 10 Avg length: 179,4 Avg pI: 8,88
Protein ID Length (AA) pI
3bvr0 78 8,70879
3NYyA 104 5,71285
A0A7S5QXQ2 201 9,21706
A0A7S5R4H8 201 9,21706
A0A7S5RCX9 202 9,40557
A0A7S5RDC4 202 9,33123
A0A7S5RFT3 202 9,40557
A0A7S5UYZ2 201 9,21706
A0A7S5UZF9 202 9,33123
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_35600
1fedL
 106 42,8% 56 1.549E-05
2 phalp2_20859
6H4ds
 4 36,2% 58 1.549E-05
3 phalp2_20443
3oSz5
 1 38,3% 60 3.747E-04

Domains

Domains [InterPro]
GH24
Representative sequence (used for alignment): 3bvr0 (78 AA)
Member sequence: A0A7S5USA3 (201 AA)
1 78 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Rhizobium phage RHph_TM3_3_9
[NCBI] 		2509558 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN988470 [NCBI]
CDS location
range 17144 -> 17749
strand -
CDS
ATGCCGATCAACAAGATACTACCGAGTAAGCGCGCCGCCGTCGCGATCGCTTCGATCATCAGTCTTTCCGCCGGTGGTTACGTGACCATGTCTTCCGGTTACAAAGTGCATGACGACGTGGCGCTTGCGTCGACCTATCTGATTGGTCCGTGGGAAGGGCGCGAACTGGTCGCGTATCTGGACAAGCTGGCAAAGCCGCCCGTCGTGACGATCTGCGACGGTGACACGACGAACGTCAAGCTTGGTATGCGCGAAACTCCGGCCGGCTGCGACAAGCGATTGCAGTCGAAAATGGAAACGGTGTATCGGCCGGCGCTGGTCAAATGCGTGATCGATTTCGACAAACACCCTGTCGCATGGCGCGCAATGGCTGATTCGATCGCTTGGAACATCGGCACCGGTGCCGCGTGTAATTCCACGGCGATCAGGATCGTCAACGACGCGATGCGTAAGAAGACTGTCCCGGATTACGTCGCAAGCTGCAAAGCCGCCACGGCGTTCAACAAGGCCGGCGGTAAGGTCTATATCGGGTTGGTCAACCGGCGCGAAATGGGCGACAAGACCCGAATCGGCGAAGCTGAAATGTGCGTGACAGGTGCCCAATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016020 membrane cellular component None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3bvr0) rather than this protein.
PDB ID
3bvr0
Method AlphaFoldv2
Resolution 92.82
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50