Protein

Protein accession
A0A7S5R8F6 [UniProt]
Representative
5H0F4
Source
UniProt (cluster: phalp2_4879)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MPNALVIDISHHQPDPDWKALKKGGTIGVILKATEGSSYVDPTYGKRNVEARAAGLCVATYHFLKPGDTAASQMDFYVKTVKPKDGDRLIIDYEANGLKISDLETAIKRLAQIAPKCEISVYGANGFLGAQLGGARNDVLASTSLWIASYTSASVPTNRDLKGTWPVWSLWQYSDKGRVDGLDVNVDVNRWNGDPDKLPGWFNSSLMPEETVTPVPPTPPVTTQPVVIEIKVPEGVSVVTVVNGKMLA
Physico‐chemical
properties
protein length:248 AA
molecular weight:26819,2 Da
isoelectric point:5,94
hydropathy:-0,19
Representative Protein Details
Accession
5H0F4
Protein name
5H0F4
Sequence length
381 AA
Molecular weight
41891,07270 Da
Isoelectric point
4,23970
Sequence
VSVLRGKCSWFGGPDDDGVAPDEPLAFIHDTADQPSLFLDQQPPDTTGLARRLDPEQFYLAMRWDYDETPRQMLLEEVALVRAIKTGIALTALPADWGPHQDTDRIADISPGLMDALGIETDDEVEIIFPYQGVEPMAEVVKCIDISHHQDFPDFQKVRAAGVIALVHKCSEGSSYVDPNRGKNCKNAIDAGIAVATYHWLSPGSSATQQMRFYLDTLQPVDGERVVIDYEEEGCTLDDLHEAVEALLADPRDLQITVYSGHLLKEQLNGNRDELLADNTDLWLAQYTSGTPSWSKGTYPEYTLWQYSESGTVNGISGSLVDLNRFNGSDDELLTWINPFGSVEPPQPAPPEMASVHLNLQTSGQVAISIAVNGEVIYGDA
Other Proteins in cluster: phalp2_4879
Total (incl. this protein): 11 Avg length: 337,4 Avg pI: 4,94
Protein ID Length (AA) pI
5H0F4 381 4,23970
15Hme 401 4,37623
1NEna 384 4,47467
4XNB7 394 4,56056
5GCih 388 4,13262
5GVgz 385 4,35179
6K7Gd 386 4,44608
A0A7S5URT1 248 5,94004
A0A7S5URW3 248 5,94004
A0A7S5URZ0 248 5,94004
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_39129
2CcXt
 6 22,2% 310 2.079E-22
2 phalp2_20768
5zEJO
 1 27,4% 248 2.255E-10

Domains

Domains [InterPro]
Unannotated
GH25
Disordered region
Representative sequence (used for alignment): 5H0F4 (381 AA)
Member sequence: A0A7S5R8F6 (248 AA)
1 381 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Rhizobium phage RHph_TM3_14A
[NCBI] 		2509560 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN988472 [NCBI]
CDS location
range 1315 -> 2061
strand -
CDS
ATGCCCAACGCTCTTGTAATCGATATCAGCCACCACCAGCCGGACCCGGACTGGAAGGCACTTAAAAAGGGTGGCACCATTGGTGTCATCCTGAAAGCCACGGAAGGCTCCAGCTACGTTGACCCCACCTACGGCAAGCGCAACGTTGAAGCACGCGCCGCTGGGCTGTGTGTGGCAACCTACCACTTCCTGAAGCCGGGTGATACCGCAGCTTCACAGATGGACTTCTATGTGAAGACGGTGAAGCCTAAGGACGGCGACCGGCTCATCATCGACTACGAAGCCAACGGGCTCAAGATCAGCGATCTTGAAACAGCCATCAAACGGCTGGCGCAGATCGCACCCAAGTGCGAGATTTCGGTGTACGGGGCAAACGGCTTCCTCGGTGCACAGCTTGGTGGCGCACGGAACGATGTGCTTGCGTCCACGTCTCTGTGGATCGCCAGCTACACATCAGCCTCGGTGCCGACAAATCGGGACCTGAAGGGGACGTGGCCTGTATGGTCGCTCTGGCAGTATTCGGACAAGGGGCGTGTGGATGGCTTGGACGTCAATGTGGATGTCAACCGCTGGAACGGCGACCCGGACAAGCTTCCGGGATGGTTCAATTCCAGTTTGATGCCAGAGGAAACGGTTACCCCCGTGCCCCCTACACCGCCGGTCACCACGCAACCAGTTGTGATTGAAATAAAGGTCCCGGAAGGCGTATCCGTCGTCACTGTTGTCAATGGGAAGATGCTTGCGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5H0F4) rather than this protein.
PDB ID
5H0F4
Method AlphaFoldv2
Resolution 90.28
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50