Protein

Protein accession
A0A7R7G2D5 [UniProt]
Representative
7qQKH
Source
UniProt (cluster: phalp2_15054)
Protein name
MurNAc-LAA domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MATYNVHGGHNGIVMGANSQFGKEHILDRQVKDALISKLRALGHTVYDCTDEVGATQSANLRNIVAKCNAHKVDLDISLHLNAFNGTANGVEVCYYDQQALAAKVSKQLSDDIGWSNRGAKPRTDLYVLNNTAAPAILIELGFIDNAGDMGKWNTDKIANSIVKALTGQTVGGGSTGGSTGGGGTVAPPSDGRYGTLTVTGDVVNIRKGPGTNYDIAPGTGYQGDGKARQGETYIVWAEQNGWYNVGGDAWIIKDFVDFIPAPQANEVGKLVVALVDGLYTYNSANWNDKGKQINKGTALTITEVLTVDGYKMYKTKSGIYITAAKEYVVVK
Physico‐chemical
properties
protein length:332 AA
molecular weight:35314,2 Da
isoelectric point:6,59
hydropathy:-0,26
Representative Protein Details
Accession
7qQKH
Protein name
7qQKH
Sequence length
318 AA
Molecular weight
35771,41430 Da
Isoelectric point
6,01580
Sequence
MSFQRFTSNAGHSYHTDGAQGNGYSEHAEAMKYNNEFIKQMKQVGYTVTNTTSEAKGQQAILSEQAHKANEVDRTGRLDVSFHFNSASASATGVEVLYYDQEVLASQVSQAIANALGIRNRGAKENKGLYFLANTNAPAILIEVAFISNAGDMKQATSKRVQAVAAIVKALTGKETPSAGFTGTWWRYARATHHIRTRPDWDSPVAFDIPNYYAVNMNYDKRENEFVEIEFQGQKGWFKDSLTEYWFEEKPTETYVVTAETVHFRDQQDWDSPVVQTKKKGDTVEVLREMDKPGWLQVILTEGVIGYIPDAPHYVKKV
Other Proteins in cluster: phalp2_15054
Total (incl. this protein): 6 Avg length: 333,2 Avg pI: 7,50
Protein ID Length (AA) pI
7qQKH 318 6,01580
P89923 257 6,09595
A0AAE7SS33 364 8,89788
A0AAE7VHI0 364 8,69384
A0AAE7VHL0 364 8,69384
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_11988
35NoL
 2 31,2% 205 1.712E-19
2 phalp2_7714
6PwWD
 2 28,2% 209 7.674E-13
3 phalp2_29154
7mKv1
 17 28,7% 226 2.489E-09

Domains

Domains [InterPro]
Ami3
Unannotated
Representative sequence (used for alignment): 7qQKH (318 AA)
Member sequence: A0A7R7G2D5 (332 AA)
1 318 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage vB_BceM_WH1
[NCBI] 		2795294 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
LC597490 [NCBI]
CDS location
range 35186 -> 36184
strand -
CDS
ATGGCAACTTATAACGTACACGGTGGTCACAACGGAATCGTAATGGGAGCAAACTCTCAATTTGGGAAAGAGCACATCTTAGACCGTCAGGTAAAAGACGCTTTAATCTCAAAACTTCGTGCCCTTGGTCATACAGTTTATGACTGTACTGATGAGGTAGGAGCAACTCAGTCTGCTAACCTTCGAAACATCGTAGCTAAGTGTAATGCTCATAAGGTAGACTTAGACATCTCGCTTCACTTGAATGCGTTCAATGGAACTGCAAATGGTGTTGAGGTTTGCTATTATGACCAACAAGCTCTAGCAGCTAAGGTTTCTAAACAGCTTTCTGATGACATCGGCTGGTCTAACCGTGGTGCTAAACCTCGTACAGACCTTTATGTGTTAAACAACACTGCTGCTCCAGCGATCTTAATCGAGCTTGGCTTCATTGACAACGCTGGTGACATGGGTAAATGGAACACAGACAAAATCGCTAACTCTATTGTTAAAGCTTTAACTGGTCAAACAGTAGGTGGCGGCTCTACTGGTGGAAGCACTGGTGGTGGCGGTACTGTAGCTCCTCCATCTGATGGTCGTTACGGAACATTAACTGTAACAGGTGATGTTGTAAACATTCGTAAAGGTCCAGGCACAAACTACGATATCGCTCCTGGTACTGGTTATCAAGGTGACGGTAAAGCTCGCCAAGGCGAAACTTACATCGTATGGGCTGAACAAAACGGATGGTACAATGTCGGCGGTGACGCTTGGATTATCAAAGACTTCGTGGATTTTATCCCAGCGCCTCAAGCTAATGAAGTAGGCAAGCTTGTTGTGGCGCTAGTTGATGGATTGTACACTTACAACTCTGCTAACTGGAATGACAAAGGGAAACAAATCAACAAAGGCACAGCATTAACAATTACTGAAGTGCTTACTGTAGATGGATACAAAATGTATAAAACGAAATCTGGCATTTATATCACAGCTGCAAAAGAGTACGTAGTAGTTAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7qQKH) rather than this protein.
PDB ID
7qQKH
Method AlphaFoldv2
Resolution 93.63
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50