Protein

Protein accession
A0A7L7SJK7 [UniProt]
Representative
6Tpcb
Source
UniProt (cluster: phalp2_8157)
Protein name
Endolysin, protease M23 domain
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MTDAYYLPFGPEVKLDRPFGVKPVDEWAAPAGEPIRAAGDGVVVFAGPVEDKFYTSNFAKNLDYSGDVVVLKMSGPTGPFFEYRNPSEIEVNSNDRVEAGQIIALAGEESTHVGALPWRFNLSSRTAGRVNPRLYQTEYWLENATLPEPEGHEGRVPEPTKIEEPAVATPKRSRRGSRTAEPVATEESIVVSGAIDASSLDAAPPAEPVDATLSDVAPPAAPIDSGVSSDD
Physico‐chemical
properties
protein length:231 AA
molecular weight:24695,0 Da
isoelectric point:4,49
hydropathy:-0,39
Representative Protein Details
Accession
6Tpcb
Protein name
6Tpcb
Sequence length
267 AA
Molecular weight
28563,43910 Da
Isoelectric point
4,71476
Sequence
MGGYYLPFDRTIRLGQQFGWNPGLGPNPAGGHNGDDWLTPVGTPVRAAGDGEVVFAGQFDSTYEDNFGWNLHYGGLMVVLNMDGAEGPYFEYGHNSRILVSAGQRVQAGQIIAITGNTDGNTGISTGPHCHVGALPPNYNLGTNTYGRVNPRLYMTEYWDGSINLASAGTITTSEEDDMPSANEIARAILDFKVDAVTGGQINLGAFLAEARHDNNKIVENTAAWLMPEVVALRELVKQLSVAQGVVIDYNAIAKAVNDDAASRMKG
Other Proteins in cluster: phalp2_8157
Total (incl. this protein): 26 Avg length: 258,2 Avg pI: 4,76
Protein ID Length (AA) pI
6Tpcb 267 4,71476
1dbtB 307 4,79462
1hS3X 280 4,72266
1hTXa 275 4,63195
1hTh1 238 4,59244
1joVn 268 4,73778
2LBEV 293 4,75000
2LBWd 305 4,65588
3PsEK 240 5,32277
3PsG7 286 5,18181
3PsUC 236 6,28926
3V3Ji 239 4,62450
3V3ws 242 4,60472
3VCYy 238 4,53168
3X81A 228 4,63570
4LRgK 297 4,40527
4MZfK 246 4,42704
4XR0u 224 4,62353
5BYie 228 4,74932
6SUGo 280 5,02192
71yTa 233 4,56840
7yYvf 294 4,70027
7yd5L 239 4,77995
fsiA 268 4,67628
A0A5B8WHL5 231 4,48792
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_33817
1joRs
 29 41,0% 202 3.418E-47
2 phalp2_8917
3eyO9
 2 42,6% 169 1.072E-35
3 phalp2_14782
6W4yG
 33 31,2% 195 2.593E-22
4 phalp2_35865
4LryU
 8 29,4% 214 4.774E-22
5 phalp2_33390
6Q97d
 9 30,1% 212 2.192E-21
6 phalp2_14600
5kHaZ
 35 30,3% 254 5.465E-21
7 phalp2_276
6CCkj
 17 35,5% 197 1.004E-20
8 phalp2_4234
40ve1
 8 31,3% 185 1.611E-16
9 phalp2_40532
4HCiG
 1 28,9% 176 5.361E-16
10 phalp2_40313
3epNU
 22 27,0% 192 1.057E-10

Domains

Domains [InterPro]
Unannotated
Disordered region
Representative sequence (used for alignment): 6Tpcb (267 AA)
Member sequence: A0A7L7SJK7 (231 AA)
1 267 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Arthrobacter phage Paella
[NCBI] 		2759388 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MT771347 [NCBI]
CDS location
range 2661 -> 3356
strand +
CDS
ATGACTGACGCATACTACCTGCCTTTCGGGCCCGAAGTAAAACTCGATCGTCCCTTCGGCGTAAAGCCCGTTGACGAATGGGCGGCTCCCGCTGGTGAACCCATCAGGGCTGCCGGAGATGGAGTAGTTGTATTTGCTGGTCCGGTAGAAGACAAGTTCTACACTAGCAACTTTGCAAAGAATCTTGACTACAGCGGTGACGTAGTCGTCCTTAAGATGAGCGGTCCTACCGGTCCGTTCTTTGAGTACCGCAACCCTTCTGAAATCGAAGTCAACTCGAATGATCGCGTTGAGGCCGGTCAGATCATCGCGCTCGCTGGCGAAGAGTCTACCCACGTTGGTGCTCTTCCTTGGCGATTCAACCTCAGCTCCCGGACTGCCGGTCGAGTTAACCCTCGACTGTACCAGACCGAGTACTGGCTGGAGAATGCTACTTTGCCTGAGCCTGAAGGACATGAGGGTCGTGTTCCGGAGCCGACCAAGATTGAAGAACCTGCTGTTGCCACACCTAAGCGTAGTCGGCGTGGTTCTAGAACTGCCGAGCCGGTAGCCACCGAAGAGTCGATCGTCGTTAGCGGCGCTATTGACGCTTCCTCTCTGGATGCCGCTCCTCCGGCGGAGCCTGTTGACGCGACTCTTAGTGATGTAGCTCCTCCGGCTGCGCCTATCGATTCCGGCGTTTCGTCTGACGACTAA

Gene Ontology

Description Category Evidence (source)
GO:0006508 proteolysis biological process None (UniProt)
GO:0008233 peptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6Tpcb) rather than this protein.
PDB ID
6Tpcb
Method AlphaFoldv2
Resolution 66.02
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50