Protein

Protein accession
A0A6M5C9F4 [UniProt]
Representative
3e8ux
Source
UniProt (cluster: phalp2_1815)
Protein name
MurNAc-LAA domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MANELIGIDIAHGENTFDTGSKGVKVNGVGYEEHHSSARIALLLDKMLKHNGFRTTFAQQPYQNDVPLNQRTNFYDAQKVDLGFSIHHNAGPSSARGLCAFYWNSSKEGFEAADDYADLVKEYGYPQYSGGLEPSRLNHWTNFAMLRDTDAVWLLTENGFMTNPEDFEFIFGSKKEKFAYDIAEIHAKVACAFFKRDFKPLSSGQANSTPIPAQEVKGVISIGKGSSVTVKSTATHYETGQPIATHVKGSKYTVLQVKGVNKGYSKKAYLLSGIVSWVLEQDISESGVKNGYDTPTTPAPAPKPAPVAPKKRYVVLPRTANEWRIYPLDKAPVVKNALPNRLKPAKFGGLTYEILKDHGGHVYEIKTGDFGRVKIYGAPITGASIITK
Physico‐chemical
properties
protein length:388 AA
molecular weight:42686,8 Da
isoelectric point:9,02
hydropathy:-0,41
Representative Protein Details
Accession
3e8ux
Protein name
3e8ux
Sequence length
398 AA
Molecular weight
42765,40300 Da
Isoelectric point
9,07710
Sequence
MVKSDGRTIGKTIGLDYGHGSNTFPPGKGVYKDGVGYAEHDFNAKLGLAIKELLEHNGFEVVEGQGAFEPEVGLTTRTNLYNRENVDIVFSVHANAGNNSVDGRCAFYWHTSSSGKRLAEYVIDEIKDAGYSTHGNGLHASQPGSWTNLHITRETKMPAVLVEHGFMTNDSDFEFIFGSKQEEYIEDMARADVKAICRYFGVSFKDLDGAVSKATPKTKVKSSVSSSGKSSGKSSGKSVTQMANEVIAGKHGSGHENRRKSLGISKSKYEKVRAEVNRRARGGSPKPKANLTVDGKWGKSTTEALQKALGTPEDGIISNQSRNSVTEALYGNTVRYGSGGSMVIEALQKKVGAKADGLLGPATVRALQSYLGTPVDGVLSRPSMVVEEMQKQLNAGTF
Other Proteins in cluster: phalp2_1815
Total (incl. this protein): 11 Avg length: 360,3 Avg pI: 9,71
Protein ID Length (AA) pI
3e8ux 398 9,07710
1oy3J 428 9,75550
2YvL6 313 10,33578
3ATB9 372 9,81359
5i4UQ 300 9,48712
7sJr8 356 9,47674
7sdpb 350 10,05173
7wMIT 409 9,88547
8MyGw 330 9,64146
ug4o 319 10,24140
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_6489
uh4U
 19 42,6% 286 7.459E-58
2 phalp2_36282
aPPg
 2 33,9% 289 3.213E-50
3 phalp2_32229
7egmh
 11 27,8% 320 4.605E-31
4 phalp2_20638
4NMLJ
 3 28,4% 327 3.810E-26
5 phalp2_29154
7mKv1
 17 22,9% 374 4.060E-25
6 phalp2_22102
65fHc
 3 23,9% 397 1.459E-22
7 phalp2_29409
1gO7O
 3 24,9% 325 6.697E-20
8 phalp2_9715
3MOw5
 5 24,0% 325 5.183E-17
9 phalp2_31486
3PO9t
 18 28,2% 326 1.637E-16
10 phalp2_40616
7KnbL
 4 23,4% 315 1.178E-13

Domains

Domains [InterPro]
Ami3
CW_7
Unannotated
Representative sequence (used for alignment): 3e8ux (398 AA)
Member sequence: A0A6M5C9F4 (388 AA)
1 398 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF08230

Taxonomy

  Name Taxonomy ID Lineage
Phage Microcystis phage MaeS
[NCBI] 		2736190 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MT362618 [NCBI]
CDS location
range 21114 -> 22280
strand -
CDS
GTGGCAAACGAATTAATCGGAATTGATATAGCTCATGGTGAAAATACTTTCGACACTGGATCAAAAGGAGTAAAGGTTAATGGAGTAGGTTACGAAGAACACCACTCAAGCGCAAGGATCGCGTTATTGCTTGATAAAATGTTAAAACATAACGGATTCCGGACAACTTTCGCTCAACAACCTTACCAAAATGATGTTCCTTTGAATCAACGTACAAACTTTTACGATGCTCAAAAGGTAGACTTAGGCTTCTCTATTCATCATAACGCTGGTCCTTCTTCAGCTAGAGGTCTTTGTGCTTTCTATTGGAACTCAAGCAAAGAAGGTTTCGAAGCTGCTGATGATTATGCTGATTTAGTCAAGGAGTACGGCTACCCTCAATACTCTGGTGGACTTGAACCTTCTCGTTTAAATCACTGGACTAACTTCGCGATGTTACGCGATACTGATGCTGTTTGGTTATTAACAGAGAATGGTTTCATGACTAATCCAGAGGACTTTGAGTTCATCTTCGGATCAAAGAAAGAAAAATTTGCTTATGATATTGCAGAAATTCACGCGAAAGTAGCATGTGCTTTCTTCAAGAGAGACTTCAAGCCACTTTCTTCTGGTCAGGCCAACAGTACGCCTATTCCAGCACAAGAGGTTAAAGGAGTTATTTCTATCGGCAAAGGTTCAAGTGTAACGGTTAAGTCTACAGCGACTCATTACGAGACGGGTCAACCAATCGCTACTCACGTTAAAGGTAGTAAGTACACTGTACTTCAGGTGAAAGGTGTTAATAAAGGATATTCTAAGAAGGCTTACTTGTTATCTGGCATTGTTTCATGGGTACTTGAACAAGATATCTCTGAAAGTGGTGTAAAGAACGGTTACGATACACCAACGACTCCAGCTCCGGCTCCTAAACCAGCTCCGGTAGCTCCTAAGAAGCGTTATGTTGTTTTACCTCGTACAGCAAACGAATGGAGAATCTATCCATTAGATAAGGCTCCAGTGGTTAAAAATGCACTTCCTAACCGCTTAAAGCCAGCTAAGTTCGGTGGATTAACTTACGAGATCCTTAAAGATCATGGTGGACACGTTTATGAAATCAAAACAGGTGACTTCGGACGAGTTAAAATTTACGGAGCTCCAATTACAGGGGCAAGTATTATAACTAAGTAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3e8ux) rather than this protein.
PDB ID
3e8ux
Method AlphaFoldv2
Resolution 87.78
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50