Protein

Protein accession
A0A6M3T8K4 [UniProt]
Representative
4a5OU
Source
UniProt (cluster: phalp2_25622)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSDAAFNPSLDLTLAHEGGFVNHPKDPGGATNKGVTQKVYDAYRRLNGLATRSVRFIEDAEVAEIYRKNYWNAAGCNSLPAGVDYAVFDYAVNSGVSRSIKDLQRTVNSVGNMVGLSLKIAVDGAVGPATIDAVCKIANADEVAFIESFCNRRMDFLRSLKTYSTFGKGWQRRVLGDKPNPTADDGDHGVIDYAVKMAKADLTYPLKPEQLPTPVGAKAGEVNGKGVEADKAVTKSPEGVGAIAAGVGVTGATAFQAADAVKAHIDDTTIGRIAAIVFGLLMLAGVGLVVWQFIQRRKEQKAA
Physico‐chemical
properties
protein length:303 AA
molecular weight:32135,1 Da
isoelectric point:8,30
hydropathy:-0,10
Representative Protein Details
Accession
4a5OU
Protein name
4a5OU
Sequence length
367 AA
Molecular weight
40004,17140 Da
Isoelectric point
8,86365
Sequence
MLANYKTCLAAVLKYEGGFSNHPSDPGGATMKGITQKVYDVWRRKQGLGIQSVRNISQPEVESIYKNNYWDVVRGDDLPSGLDLAVFDYAVNSGPGRAIRQLQKVLGVQQTGVMNAATIAAAKKNPESWAALCNERLAFMKRLDTWPVFGKGWESRVNDVRKKAGSLSSLWPVPEVEPKAEPKPDIDITAAQKRLSFLSYPLGSIDGKIGPLTRSAIRDFQDANGEPVTGNLDKRTFDLLMSDSALKRPVSPEREALTAVDLKNQGSTIVTAADSIKKNITTAGAALAGASGVASQVSDAKDQLQSIQDAISTGHTGLDWAKDNWQMILIVILLVVVLFCIVKCWELATSVENERVRQAKTGENVRY
Other Proteins in cluster: phalp2_25622
Total (incl. this protein): 14 Avg length: 311,4 Avg pI: 7,76
Protein ID Length (AA) pI
4a5OU 367 8,86365
1px5j 389 5,48402
3611q 361 6,00222
4dCln 367 5,86177
4wVbd 367 8,25377
6Ntj5 343 5,72973
8i5In 346 7,68897
A0A1Y0T0G4 249 9,74970
A0A6M3T8C8 303 8,28640
A0A6M3T9W2 316 8,98046
A0A6J5Q0A1 176 6,82411
A0A6J5RYZ7 303 8,95725
A0A9E7J0U3 169 9,60935
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24331
3Q7Cb
 1 38,4% 247 1.091E-51
2 phalp2_19754
7Eauj
 1 30,7% 338 2.083E-49
3 phalp2_20429
3gob6
 1 30,2% 245 5.404E-32

Domains

Domains [InterPro]
GH108
PG_1
Unannotated
Unannotated
Representative sequence (used for alignment): 4a5OU (367 AA)
Member sequence: A0A6M3T8K4 (303 AA)
1 367 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF05838

Taxonomy

  Name Taxonomy ID Lineage
Phage Sphingomonas phage Kharn
[NCBI] 		2686312 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN734439 [NCBI]
CDS location
range 40557 -> 41468
strand +
CDS
ATGTCGGACGCCGCATTCAACCCTTCATTGGACCTAACGCTTGCCCATGAAGGCGGCTTCGTCAATCATCCGAAAGACCCCGGCGGCGCGACGAACAAGGGCGTAACGCAAAAGGTCTATGACGCCTATCGGCGGCTGAACGGCCTTGCGACCCGTAGCGTTCGCTTCATCGAAGACGCCGAAGTCGCCGAAATCTATCGCAAGAACTATTGGAACGCCGCCGGATGCAACAGCCTTCCGGCTGGCGTCGATTACGCCGTTTTCGACTATGCGGTCAATTCGGGCGTGTCGCGGTCCATCAAAGACCTTCAGCGCACGGTCAATAGTGTGGGCAACATGGTTGGCCTGTCGCTGAAGATTGCCGTTGACGGGGCGGTTGGCCCGGCGACAATCGACGCCGTATGCAAAATCGCGAATGCCGACGAAGTGGCGTTCATCGAAAGCTTTTGCAACCGTCGTATGGATTTCCTTCGTTCGTTGAAGACGTATTCGACGTTCGGCAAAGGCTGGCAACGTCGCGTTCTTGGCGACAAGCCGAACCCGACCGCCGACGACGGCGACCACGGCGTCATTGACTACGCCGTGAAGATGGCAAAGGCCGACTTGACGTATCCGTTGAAGCCTGAACAGCTTCCGACGCCGGTTGGCGCGAAGGCTGGCGAAGTCAACGGCAAGGGCGTTGAAGCGGACAAGGCCGTCACCAAGTCGCCCGAAGGCGTCGGCGCAATCGCGGCTGGCGTCGGCGTTACCGGCGCAACGGCGTTCCAAGCGGCGGATGCTGTCAAAGCCCACATTGATGATACGACCATCGGACGTATCGCCGCAATTGTGTTCGGCCTGTTGATGCTTGCGGGCGTCGGATTGGTCGTTTGGCAGTTTATCCAGCGTCGCAAGGAACAGAAAGCGGCATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0016020 membrane cellular component None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4a5OU) rather than this protein.
PDB ID
4a5OU
Method AlphaFoldv2
Resolution 78.82
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50