Protein

Protein accession
A0A6M3T7J4 [UniProt]
Representative
4tgt3
Source
UniProt (cluster: phalp2_31603)
Protein name
Peptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNSVRRITVIFALALGIFALSIPSAEAATLRSSAMASAKTQKGAKYVYGAEGGYSRGYDCSGLVYWAYRQHGKTLPRVAQDQYNKSQKVSPSSRRAGDLIFIRDSRGRVYHAGIFTGVRNGVGYMLNANTGSYRGRKVVEAPIKEYTAGSPTAVYGRY
Physico‐chemical
properties
protein length:158 AA
molecular weight:17219,4 Da
isoelectric point:10,20
hydropathy:-0,31
Representative Protein Details
Accession
4tgt3
Protein name
4tgt3
Sequence length
403 AA
Molecular weight
42893,89970 Da
Isoelectric point
4,75449
Sequence
MAERFGDYTSAVNRVSQNLRALLPNTTAAGMQKRTPPLSSYITQLQKSGGGYQTQTGAGGGYNTNIGGSGLLGFKGSNPQMELFSFLNAGPKSYQDMLAQNQFNPKTSVGQVTQSNQNASVGGGNLAGTMQWRDLMEQAGAELQVPWQVLASIMAIESQGNNVNDPGGAMGLMQIMPQYWSQLAQQYGGNLQDPRTNIFTAAAILRQNYERYGSWSSAAAAYFGGAGAFNDDGSYSGSSDSYGTDIGAYVSAFDGYMQQLEYGVPTVGETFNGGNPATPNASHALAAAMSAQGAPYIWSGESWEEGGFDCSGLMQWAYQQAGIQLPRTAAEQYNATKRITSQELQPGDLIFFAGTTDAPGITHVGMYIGNGQMIQAPKEGDIVKIVSINDAYWSQHTVGYGRV
Other Proteins in cluster: phalp2_31603
Total (incl. this protein): 10 Avg length: 261,9 Avg pI: 8,63
Protein ID Length (AA) pI
4tgt3 403 4,75449
1NJqv 427 4,84901
5Fpbo 417 6,97962
6P1uI 419 9,18483
A0A2U8UQM8 158 10,19588
A0A2U8UQZ9 158 10,14715
A0A5J6D8A6 161 10,02814
A0A6M3SV16 160 9,81326
A0A7G9A224 158 10,19588
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_7359
4vhzG
 1 29,0% 279 3.865E-21
2 phalp2_14727
6Famy
 14 30,0% 276 7.181E-19
3 phalp2_2590
6EE0m
 7 25,1% 338 1.709E-18
4 phalp2_16784
1bkDr
 2 25,8% 290 7.169E-16
5 phalp2_28557
7UTPg
 9 25,3% 351 1.692E-15
6 phalp2_14723
6DHC0
 1 26,0% 284 8.269E-11

Domains

Domains [InterPro]
Disordered region
Unannotated
Unannotated
Representative sequence (used for alignment): 4tgt3 (403 AA)
Member sequence: A0A6M3T7J4 (158 AA)
1 403 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage CricKo
[NCBI] 		2725620 Bingvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MT310854 [NCBI]
CDS location
range 31714 -> 32190
strand +
CDS
ATGAACAGCGTGCGCAGAATCACCGTCATATTCGCTCTGGCCTTGGGCATCTTCGCCTTATCCATACCCAGCGCGGAGGCCGCAACTCTCCGGAGCTCCGCCATGGCTAGCGCCAAGACCCAGAAGGGCGCTAAGTACGTCTACGGAGCCGAAGGCGGCTACAGCCGGGGTTACGACTGCTCCGGCTTGGTCTACTGGGCGTACAGGCAGCACGGCAAGACGCTGCCCCGCGTTGCTCAGGACCAGTACAACAAGTCGCAGAAGGTCTCCCCCAGTTCTCGGAGGGCTGGGGACCTGATCTTCATCCGCGACAGCCGGGGGCGTGTCTACCACGCAGGTATCTTCACCGGCGTCAGGAACGGAGTTGGGTACATGCTCAACGCGAACACCGGCTCGTATCGTGGCCGGAAGGTCGTCGAGGCTCCAATCAAGGAGTACACGGCGGGCTCGCCCACGGCCGTTTACGGACGATATTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4tgt3) rather than this protein.
PDB ID
4tgt3
Method AlphaFoldv2
Resolution 69.51
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50