Protein

Protein accession
A0A6M3BET4 [UniProt]
Representative
6ZCjl
Source
UniProt (cluster: phalp2_29108)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MEVAKRNYGVDVSSYQDSNVANYSGAKFAIVKVSEGLDYRNPKAGSQVSTAKDSGMLPMAYHYGRFSSNSNVAVQEANYAVNSAKAVGLNAGSYLALDYEQGSGNETGGNAGDNTTAILAFLDTIVNAGYQPLLYSGAALFKSKIDTGKVLAKYPNCLWVASYPVSGAVSKPDFGYFPSMDGVAIWQFTDNWRGLNVDGNISLIDLKTDGKPVAQPSKPTIKQSTPQSWVDDIGDTWYKEEGKFYPNGTINIRYGARTTSDIIGTVTKGDCVKYDAYSRHGGYVWIRQPRADGEPGFLVCRQGNDPWGTFK
Physico‐chemical
properties
protein length:311 AA
molecular weight:33690,1 Da
isoelectric point:6,73
hydropathy:-0,41
Representative Protein Details
Accession
6ZCjl
Protein name
6ZCjl
Sequence length
178 AA
Molecular weight
19808,98460 Da
Isoelectric point
8,67849
Sequence
LYSGAALLKSKIDTGKVLAKYPNCLWVASYPVSGATSEANFGYFPSMNGVVIWQFTDNWRGLNVDGNISLVDLKTDGKPVDQPSKPTIKQSTPQSWVDDIGDTWYKEEGKFYPNGTINIRYGARTTSDIIGTVTKGDCVKYDAYSRHGGYVWIRQPRANGEYGFLVCRQGNDPWGTFK
Other Proteins in cluster: phalp2_29108
Total (incl. this protein): 6 Avg length: 220,2 Avg pI: 7,74
Protein ID Length (AA) pI
6ZCjl 178 8,67849
7NwgU 178 8,66792
7wNgY 186 5,41155
n8tr 154 9,37791
A0A6M3BEM5 314 7,57819
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_25839
5j1l4
 12 31,1% 180 6.620E-18
2 phalp2_38217
7u45O
 5 25,8% 182 1.140E-14
3 phalp2_144
5oGmc
 8 33,8% 133 4.034E-12
4 phalp2_6211
68mJi
 3 27,4% 131 7.464E-10

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 6ZCjl (178 AA)
Member sequence: A0A6M3BET4 (311 AA)
1 178 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactobacillus phage JNU_P11
[NCBI] 		2686381 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN830257 [NCBI]
CDS location
range 23642 -> 24577
strand -
CDS
ATGGAAGTAGCAAAAAGAAATTACGGTGTAGACGTATCTAGCTATCAAGATAGTAATGTAGCTAATTATTCTGGCGCTAAGTTTGCAATTGTCAAAGTATCGGAAGGTTTAGATTATCGTAATCCTAAGGCTGGCAGTCAAGTATCTACCGCAAAGGATAGTGGTATGTTGCCAATGGCTTATCACTATGGAAGATTTAGTAGCAATAGTAACGTAGCCGTTCAAGAGGCTAACTATGCAGTTAACTCAGCTAAAGCAGTTGGACTTAATGCAGGTTCCTACTTAGCATTAGACTATGAACAAGGTAGTGGTAATGAAACTGGCGGAAATGCTGGTGATAATACTACTGCAATCCTAGCTTTCTTAGACACGATCGTAAATGCTGGCTATCAACCATTGTTATACTCAGGTGCTGCGTTGTTTAAGTCCAAGATTGATACTGGTAAAGTATTAGCAAAATATCCCAACTGCTTATGGGTAGCGTCTTATCCTGTATCTGGTGCAGTAAGTAAACCAGACTTTGGTTACTTTCCATCAATGGACGGAGTAGCAATCTGGCAATTTACCGATAATTGGCGTGGTTTAAACGTTGACGGAAACATCTCTCTAATTGACCTTAAGACTGACGGTAAGCCAGTAGCCCAACCATCTAAACCAACTATTAAGCAATCAACACCACAATCTTGGGTTGATGATATTGGCGATACTTGGTACAAGGAAGAAGGCAAGTTCTATCCAAACGGAACCATTAACATTCGCTATGGTGCTAGAACCACTAGTGATATCATTGGTACAGTAACCAAGGGTGATTGTGTTAAATACGATGCTTACAGTCGCCATGGTGGTTATGTCTGGATTAGACAACCAAGAGCTGACGGAGAACCAGGTTTCTTAGTTTGTCGTCAAGGTAACGATCCATGGGGTACGTTTAAATAG

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6ZCjl) rather than this protein.
PDB ID
6ZCjl
Method AlphaFoldv2
Resolution 86.85
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50