Protein

Protein accession
A0A6M3BE13 [UniProt]
Representative
7iNFi
Source
UniProt (cluster: phalp2_7780)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MALRNLFIDVSGYQEDSVAYFQRAKDQGVMGVVVKLTEGSEDGSAYVNPRAEAQIRNAATVGLRVSCYHFARYTSDADAQNEARFFVKIAKQYGMTSDTRMVDDAEVHSVTDYNSATAAFLNEVKALGYANVGLYSMKSFFTSGILNSHGFGEAKIWDAGYGITDLGIDNAAAWQWTDNGLGMNVDTSYDFDGAFTVGSSNPGTVPSTPIPAPQPVEHVGHPATGTYTVQSGDTLSGIAAKFGTTYQILSAINGIGDPNQIWPGQVLKVTGTASQESTYYVQSGDTLSSIATKFGTTVSNLVSINHISNPNVIYVGQKIYVGEATQGQSNAYTVQAGDTLSGIAAKFGTTWQALAQKNGLANPNVIYVGQTLTI
Physico‐chemical
properties
protein length:374 AA
molecular weight:39758,6 Da
isoelectric point:4,90
hydropathy:-0,14
Representative Protein Details
Accession
7iNFi
Protein name
7iNFi
Sequence length
349 AA
Molecular weight
38585,68850 Da
Isoelectric point
4,69958
Sequence
MAELFADVAVYQRSDLAYYQMLANNGVKGVCIKLTEGSRAGSNYINPRALAQTKSALAAGLVVSFYHYSLYNGVTDAKAEADFFVSVAKQMGATANTVMVADAEAPTLYSPYADTQAFQDYIAYMGYNKQATYSMASWFWAKKLPTNRPLWVANYGVSQPGVNNVDAWQYTSTWNGMGQDMSYDYTGLFTTTSGNQVTVESGENEVQINELNRIVDYRTMGIGLAKRDAQILDAPYPWANVIKTIKSNTLWEVFQRKGGYYSLGGEQYINAGDISVTWNTGQAFGDWQGVRVKPINGDIWTQSTPDDGTGVTQLDQDMVYVVTEANVTNDQVYVNIGGWVPIDKFKVVL
Other Proteins in cluster: phalp2_7780
Total (incl. this protein): 6 Avg length: 350,3 Avg pI: 7,14
Protein ID Length (AA) pI
7iNFi 349 4,69958
1b4Ej 340 8,78731
7fEaB 354 6,20985
8lmG8 337 8,47825
b16E 348 9,76846
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_14854
7znRU
 13 43,0% 237 3.040E-49
2 phalp2_11124
5oePU
 31 27,1% 369 1.244E-47
3 phalp2_7054
8lmGo
 6 29,4% 248 2.104E-40
4 phalp2_11344
7rGpn
 1 25,3% 304 1.932E-24
5 phalp2_14510
4SuEX
 6 25,0% 367 1.010E-21
6 phalp2_17009
8mast
 2 22,6% 323 1.354E-15
7 phalp2_11865
7owpA
 74 20,4% 284 1.299E-08
8 phalp2_7658
6ucuX
 7 21,2% 324 3.041E-08
9 phalp2_40221
2t2YG
 45 19,3% 232 9.074E-07
10 phalp2_30642
6IgWY
 12 22,8% 250 1.094E-04

Domains

Domains [InterPro]
GH25
Unannotated
Representative sequence (used for alignment): 7iNFi (349 AA)
Member sequence: A0A6M3BE13 (374 AA)
1 349 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Lactobacillus phage JNU_P5
[NCBI] 		2686384 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN830253 [NCBI]
CDS location
range 26495 -> 27619
strand +
CDS
ATGGCTTTACGAAACTTATTCATCGACGTTTCAGGCTATCAAGAAGATAGCGTGGCTTATTTTCAACGTGCTAAGGACCAAGGGGTCATGGGGGTCGTTGTTAAGCTGACGGAAGGGTCGGAAGATGGCTCTGCTTATGTGAACCCTCGAGCTGAAGCACAGATTCGCAATGCGGCAACCGTTGGTTTGCGTGTTAGCTGCTATCACTTTGCACGCTATACCAGCGATGCAGATGCTCAAAACGAAGCTCGTTTCTTCGTTAAGATCGCTAAGCAGTATGGCATGACGAGTGACACTCGGATGGTTGACGATGCGGAAGTTCATTCGGTAACCGATTATAATTCCGCAACGGCCGCCTTTCTGAACGAAGTCAAGGCTCTTGGCTATGCTAACGTTGGACTTTACTCGATGAAGTCGTTCTTCACTAGCGGAATCCTTAACAGTCATGGTTTTGGCGAAGCTAAGATTTGGGATGCCGGTTATGGAATTACTGACTTAGGCATTGATAACGCCGCCGCATGGCAATGGACTGACAATGGTCTTGGTATGAACGTCGACACGTCTTACGACTTTGACGGAGCGTTCACGGTTGGTAGTTCAAATCCTGGAACGGTTCCATCTACGCCAATCCCAGCACCACAACCAGTAGAACATGTTGGACATCCGGCAACCGGCACTTACACGGTTCAGTCAGGAGATACGCTGTCTGGGATTGCGGCTAAGTTTGGAACGACTTATCAAATTCTATCCGCTATCAACGGGATTGGTGATCCAAACCAGATTTGGCCGGGACAGGTACTTAAAGTCACTGGTACAGCAAGTCAAGAATCAACTTACTACGTACAATCTGGTGACACCTTGTCATCGATTGCAACTAAGTTTGGTACGACGGTTTCGAACCTGGTAAGCATTAACCACATCAGCAACCCTAACGTGATCTACGTTGGTCAAAAGATTTACGTTGGTGAAGCTACTCAAGGGCAATCCAACGCTTATACTGTGCAAGCCGGCGATACACTGTCTGGGATTGCGGCTAAGTTTGGGACGACCTGGCAGGCTTTAGCTCAGAAGAACGGCTTGGCAAATCCTAACGTCATCTATGTTGGCCAAACGTTGACAATCTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0008932 lytic endotransglycosylase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7iNFi) rather than this protein.
PDB ID
7iNFi
Method AlphaFoldv2
Resolution 88.89
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50