Protein

Protein accession
A0A6H0QVG0 [UniProt]
Representative
6Psj3
Source
UniProt (cluster: phalp2_6283)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MNYQSTINQLKRHEGLKLKPYKCTAGKLTIGYGRNLEDKGINKSEAEEMLLRDICEVEERLFDTGLLDSQNDARKAVLINMAFQLGFNGLLGFKNMLEAVRRHEYELAGKEMLNSRWAMQTPSRAKELYDQMVTGEFQ
Physico‐chemical
properties
protein length:138 AA
molecular weight:15895,1 Da
isoelectric point:6,74
hydropathy:-0,60
Representative Protein Details
Accession
6Psj3
Protein name
6Psj3
Sequence length
201 AA
Molecular weight
22817,84050 Da
Isoelectric point
8,78931
Sequence
MTPDQQHHIRNGAICIQRATLVLLRKSANLGAEQKALLRDIAREAARIEEAIKEKYVDFNETLQRQLIFEEGLKFKPYRCTANKLTIGVGRNLEDKGISNDTAMRMLQEDIDECVGDLKTFPWFDELSENRRAALVQMRFVLGAVGLRTFKNTLNHIASGDFPRAAKGLLESKWHSQAGNRVDRLAAMLERDISHDEARKG
Other Proteins in cluster: phalp2_6283
Total (incl. this protein): 6 Avg length: 148,0 Avg pI: 7,97
Protein ID Length (AA) pI
6Psj3 201 8,78931
A0A088FB05 133 9,33833
A0A3G2YTL2 143 5,12684
A0A6J5LVG4 140 9,29919
A0A6J5NFF7 133 8,52970
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32797
2yPO8
 5731 50,3% 129 2.616E-57
2 phalp2_9780
80F6A
 154 48,0% 131 7.552E-55
3 phalp2_17008
8jNgs
 3526 41,7% 134 9.488E-51
4 phalp2_16834
1uDRT
 24 48,8% 129 1.299E-50
5 phalp2_24213
2KXlJ
 83 43,3% 143 3.393E-44
6 phalp2_6928
2KMCh
 358 42,1% 159 2.234E-43
7 phalp2_27968
RI1z
 5083 38,7% 129 3.059E-43
8 phalp2_8442
12q1i
 28 39,4% 137 2.754E-39
9 phalp2_18518
6Rxhb
 4 35,0% 134 6.283E-35
10 phalp2_14448
4FjnP
 18 40,0% 140 1.176E-34

Domains

Domains [InterPro]
Unannotated
GH24
Representative sequence (used for alignment): 6Psj3 (201 AA)
Member sequence: A0A6H0QVG0 (138 AA)
1 201 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Alteromonas phage P24
[NCBI] 		2500137 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK241539 [NCBI]
CDS location
range 35348 -> 35764
strand -
CDS
ATGAATTATCAATCAACCATTAATCAATTGAAGCGGCACGAAGGCTTGAAGCTTAAGCCTTATAAATGTACTGCCGGTAAGCTAACAATTGGTTATGGTCGCAATCTTGAAGATAAGGGCATAAACAAATCTGAAGCAGAAGAAATGCTTCTTCGTGACATCTGCGAAGTAGAGGAAAGACTTTTTGATACTGGCTTGTTAGATAGTCAGAACGATGCTCGTAAAGCAGTATTGATCAACATGGCCTTTCAGCTTGGTTTCAATGGCCTTCTTGGTTTCAAGAATATGCTTGAAGCTGTTCGCCGTCACGAATACGAATTAGCTGGTAAAGAAATGCTTAATAGCCGCTGGGCTATGCAGACCCCAAGCCGCGCTAAAGAGCTTTACGACCAAATGGTTACAGGTGAATTTCAATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6Psj3) rather than this protein.
PDB ID
6Psj3
Method AlphaFoldv2
Resolution 93.54
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50