Protein

Protein accession
A0A6G9LJH9 [UniProt]
Representative
7bNjX
Source
UniProt (cluster: phalp2_33447)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MSNSRNRVLVAALTVSLAGFGAWMKSEDFSAKPYVPTKGDVPTIGYGSTRYENGQSVKLTDPPITRQRGEQLARNLMAKDEQQFRDSLPGVKLFQEEYDLYLDFTGQFGITNWRGSSMRRDLLAGNYRQACDDLLKWRNQAGRDCSLPKNWGPKGCKGVWTRQQERHAQCIVVQVPE
Physico‐chemical
properties
protein length:177 AA
molecular weight:20064,5 Da
isoelectric point:9,25
hydropathy:-0,69
Representative Protein Details
Accession
7bNjX
Protein name
7bNjX
Sequence length
290 AA
Molecular weight
31511,25570 Da
Isoelectric point
8,28859
Sequence
MKAPAAGAASQRRRQLLAVLSVSAAGFAGWLGFEGTSPVVQVADGTGQIAQEWLLPHIPTQGDVPTIGFGSTRYEDGTPVTLVDPPITRQRAAQLARKLMSEDERRFADSLPGVTLYQEEYDVYLDFVGQYGIGNWRKSSMRRHLLAGQYRQACEALLRWRFQGGRDCSLPANWGPRGCKGVWTRQEARVAQCLAAQTQAYALAELQAFRSESGRLSGLSAALAERIDALAKTRPAIIERYTHEIRERPLPDGCFIDAGRLQQLAAALAAANAALAAGEPGRTVSLDTDD
Other Proteins in cluster: phalp2_33447
Total (incl. this protein): 23 Avg length: 174,3 Avg pI: 9,24
Protein ID Length (AA) pI
7bNjX 290 8,28859
Q5QF59 177 9,38642
C5IHR6 174 9,48048
Q6V7L5 174 9,33929
I6NW41 174 9,33923
I6X6V3 174 9,40937
A0A481V4K5 177 9,27315
L7TJR2 175 9,27315
A0A2K8HZR8 177 9,48119
A0A0B5L1J1 168 9,54740
A0A0B5L5F7 168 9,65757
A0A481V2U2 170 8,92715
A0A481V442 170 8,92715
A0A4D6CHH1 145 9,45469
A0A4D6CHL0 145 9,45469
A0A4D6CHP3 145 9,45469
A0A4D6CK29 145 9,45469
A0A6M3I0C4 176 8,96157
A0A7D5QCE8 176 8,96157
A0A7D5U564 176 8,96157
A0AAE7S9S8 181 8,88228
A0AAE9VTP4 174 9,45547
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_39083
2cctI
 5 55,6% 185 6.429E-76
2 phalp2_29467
1ADQo
 2 26,8% 190 1.408E-10

Domains

Domains [InterPro]
GH24
Representative sequence (used for alignment): 7bNjX (290 AA)
Member sequence: A0A6G9LJH9 (177 AA)
1 290 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959

Taxonomy

  Name Taxonomy ID Lineage
Phage Pseudomonas phage Epa33
[NCBI] 		2719194 Hollowayvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MT118301 [NCBI]
CDS location
range 58282 -> 58815
strand +
CDS
ATGTCGAACAGCCGTAACCGCGTGCTGGTTGCCGCGCTGACCGTCAGCCTGGCCGGCTTCGGCGCCTGGATGAAGTCGGAGGATTTCAGCGCGAAACCATACGTGCCGACCAAGGGCGACGTTCCGACCATCGGTTACGGCTCCACCCGCTACGAGAATGGCCAATCGGTGAAGCTGACCGATCCGCCGATCACCCGCCAGCGCGGCGAACAACTGGCGCGCAACCTGATGGCGAAGGACGAACAGCAGTTCCGCGACTCGCTGCCCGGCGTGAAGCTGTTCCAGGAAGAGTATGACCTGTACCTGGATTTCACGGGCCAGTTCGGCATCACCAACTGGCGCGGTAGCTCGATGCGCCGCGACTTGCTCGCCGGCAACTACCGGCAGGCGTGCGACGACCTGCTGAAGTGGCGCAACCAGGCAGGCCGCGACTGCTCTCTGCCGAAGAACTGGGGGCCGAAGGGCTGCAAAGGTGTGTGGACCAGACAGCAGGAGCGGCATGCGCAATGCATCGTCGTGCAGGTGCCGGAATGA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		RuleBase:RU003788

Tertiary structure

PDB ID
A0A6G9LJH9
Method AlphaFoldv2
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (7bNjX) rather than this protein.
PDB ID
7bNjX
Method AlphaFoldv2
Resolution 87.19
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50