Protein

Protein accession
A0A6B9SS82 [UniProt]
Representative
23Keb
Source
UniProt (cluster: phalp2_1517)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKTIIDISKHNGAVDWERVKKSGVDGVILRCGFGQDEAKQDDSRFKENADACTRLNIPFGIYIYSYARTVDKVAGEAAHIIRLANGYNLALPLFYDLEEHGTEATAAERANRYLQIVKDAGYIGGIYASEYWFKKYLTNVDTPWKWVAKYGMNTGTAGTKPDVSNVDIWQYTSRGIVNGISGRVDMSILYRGFIGDQEPQKTVKEIATEVIANKWGTGAERVQRLTDAGYNAEQVQAMVNDIIKKQEAPKAAVEEAPKAAEDKPNTYTVQAGDTLGKIAKAHHTTVAKLCEINSIKDKNKIKTGQIIRVK
Physico‐chemical
properties
protein length:310 AA
molecular weight:34385,6 Da
isoelectric point:8,69
hydropathy:-0,45
Representative Protein Details
Accession
23Keb
Protein name
23Keb
Sequence length
548 AA
Molecular weight
62180,63120 Da
Isoelectric point
8,79415
Sequence
MMLHIHIPSLPQRKEEYRRGDATIIYDDNKHAILIDGGEGDYWKQTRAYLEEKGLRHVTFVLSHWHPDHDCALRSALESSYVIVDKIYCPPIWELNTIPDGVGDYRRAAAIIGLARNLDKEIVYIPAAKTTWVKVGAIRMWLWRRKANKKDFVNYQTNNTSVSAYFPDLGYWSMGDAITTAEKYLRTYKHRKIIGFKIGHHGNACAESQCDLLEARGAKICFYNDWEPSGVGIGGTNFSKYGAKNCARHFVTLRPFYDIDIQSNGKTVVWKQDGKTWTYPLTDGEPKQETPKHDPEQSTPKLRDMSTLFGIDTSYANGAIDWDKVAPHVDFAILQCGFGQDRTSQDDKQFKRAALACERLGIPYGIYLYSYAKNQTMAEGEAKHVLRLAKGRQLSLPIYYDLEEKSLGDVAASNMWAFGKVVENAGYWCGVYSGEYYYNAHLKNVSAYTKWIARYNPNNGKQGTKPNVPNVAIWQYSSRGKVAGVSGYVDVNIAYVDLIKSVTGKDYIQAARDVWADKYGTDEERIGKLTANGFDPRIVQHFVNRLKA
Other Proteins in cluster: phalp2_1517
Total (incl. this protein): 4 Avg length: 431,5 Avg pI: 8,72
Protein ID Length (AA) pI
23Keb 548 8,79415
21vLB 558 8,72710
A0A6B9STM4 310 8,68732
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24350
3WE0c
 3 27,6% 538 2.365E-37

Domains

Domains [InterPro]
Unannotated
GH25
Representative sequence (used for alignment): 23Keb (548 AA)
Member sequence: A0A6B9SS82 (310 AA)
1 548 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Butyrivibrio virus Arian
[NCBI] 		2696357 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN882551 [NCBI]
CDS location
range 31995 -> 32927
strand +
CDS
ATGAAAACAATTATAGATATATCAAAGCATAACGGCGCGGTTGATTGGGAGCGCGTCAAAAAGTCAGGCGTTGACGGCGTTATATTGCGTTGTGGATTTGGACAAGACGAAGCAAAACAGGACGACAGCCGTTTTAAAGAAAATGCGGACGCGTGTACACGGTTAAATATTCCGTTTGGTATATACATTTATTCGTATGCGCGAACCGTGGACAAGGTAGCAGGAGAAGCAGCACATATAATCAGACTTGCAAACGGTTACAATTTGGCGTTACCGCTTTTTTACGATTTGGAAGAACACGGGACAGAAGCAACAGCGGCAGAACGTGCAAACCGTTATTTGCAGATAGTTAAAGACGCGGGATATATTGGCGGCATATATGCAAGTGAATATTGGTTCAAAAAGTATTTAACAAATGTTGATACACCGTGGAAATGGGTTGCCAAATACGGAATGAACACAGGCACAGCGGGAACAAAACCCGACGTGTCAAACGTCGATATTTGGCAGTATACAAGCCGCGGCATAGTTAACGGCATTAGTGGACGCGTTGACATGTCGATTTTATACCGTGGTTTTATCGGAGATCAGGAGCCACAAAAAACCGTTAAAGAGATTGCAACCGAAGTTATAGCGAATAAGTGGGGAACCGGAGCGGAGCGCGTGCAGAGATTGACAGACGCGGGATATAATGCGGAGCAGGTGCAAGCAATGGTTAATGATATTATCAAGAAGCAGGAAGCGCCAAAGGCAGCAGTTGAGGAAGCGCCAAAGGCAGCAGAGGACAAGCCGAACACATACACCGTGCAAGCGGGCGACACGTTGGGAAAGATTGCGAAAGCACATCATACAACAGTTGCAAAGCTATGCGAGATCAACAGCATTAAGGACAAGAACAAAATTAAAACAGGTCAGATCATAAGAGTAAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (23Keb) rather than this protein.
PDB ID
23Keb
Method AlphaFoldv2
Resolution 74.79
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50