Protein

Protein accession
A0A6B9LPC9 [UniProt]
Representative
7cnpE
Source
UniProt (cluster: phalp2_15036)
Protein name
N-acetylmuramyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTKYIALDDGHGMETAGKRTPYIPSLGRQIKENEFNRAVVKFLDQELKRCGFRTLLVAPTDVDTPLKERTDKANKAGVDAYISIHYNAFDGTFAGKNPEGFQAHVYLGHSNKKAGKLAKCILKHLAGGTKQVNRGLHESNFHVLRETHMPAVLLELGFMDNEREALLMINTDFQKECAREIAQGICEYFGVKYVPEKKANPPKTTTPTKTFYRVVTGSFKEKANAERRVAELKRKGFDSFIDYKNGWYRVITGSFQDRGNAKKRMAELKRAGFDSFLESHKA
Physico‐chemical
properties
protein length:282 AA
molecular weight:31888,1 Da
isoelectric point:9,52
hydropathy:-0,61
Representative Protein Details
Accession
7cnpE
Protein name
7cnpE
Sequence length
393 AA
Molecular weight
44059,61100 Da
Isoelectric point
9,26593
Sequence
MRKAADYLIALDDGHGLRTAGKRTPYIKSLGRQIRENEFNEAVTYFLKEELERCGFRTLLTAPTDYDTPLIMRTNLANTMGADALVSNHFNALDGEFDGPGKDPEGMSIHIYPGAKNGRELAEHVAKYLKQGTKQKYRGIIEQNLHMTREFNRAAILIENGFMDNKREALLMIDEDYQRECAREQAQGICSFFGIPCVPSNGKEPVKTVKPPKTEVKGEYVSSNVVGKRVQSIYRGTEGLDFYSKPTFNNRYLAGMLKYGYGFPTIVRKLRVEGGCMYEVKNSRGHKYYVTAAEKYVKVDGASSKPKSKHASNPKTNPRAIGEIEIVNVQSAAIIQDRPDRVTSKNLGTIAKGKTIQVTGSVRGEKSKSGYWEVIFKDDLAYITGQFGQYHAY
Other Proteins in cluster: phalp2_15036
Total (incl. this protein): 7 Avg length: 331,7 Avg pI: 8,32
Protein ID Length (AA) pI
7cnpE 393 9,26593
7wh7R 368 4,63149
7xAJS 367 6,11755
A0A5J6T764 304 9,56416
A0A5J6TA99 304 9,56416
A0A5P8PIE4 304 9,56416
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_9307
7sfyx
 22 32,7% 321 5.027E-42
2 phalp2_11491
tx2m
 34 26,0% 369 5.773E-41
3 phalp2_32481
1c5or
 14 27,3% 340 6.609E-40
4 phalp2_24300
3nP7b
 4 25,4% 389 1.699E-31
5 phalp2_16523
72lcf
 2 20,6% 364 3.678E-18
6 phalp2_17753
7uM5Y
 14 25,4% 271 2.077E-15
7 phalp2_30305
4ukUL
 3 20,6% 406 4.867E-07

Domains

Domains [InterPro]
Ami3
Unannotated
Unannotated
Representative sequence (used for alignment): 7cnpE (393 AA)
Member sequence: A0A6B9LPC9 (282 AA)
1 393 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Geobacillus phage GBK1
[NCBI] 		2686286 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN727882 [NCBI]
CDS location
range 19484 -> 20332
strand +
CDS
GTGACTAAATATATTGCCCTTGACGACGGACATGGCATGGAGACAGCAGGAAAAAGAACCCCATACATTCCCTCATTAGGTCGTCAAATTAAGGAGAATGAGTTCAACCGAGCAGTTGTGAAGTTTTTAGACCAAGAGCTCAAACGTTGCGGTTTTCGTACTCTGTTGGTTGCTCCAACTGACGTGGATACTCCACTAAAAGAACGTACTGATAAAGCAAACAAAGCTGGAGTTGACGCTTATATTAGCATTCACTACAACGCATTTGATGGAACTTTCGCAGGGAAAAACCCAGAAGGTTTCCAAGCTCATGTCTACCTCGGTCATAGCAACAAAAAAGCTGGCAAACTTGCTAAGTGCATTTTGAAACACCTCGCAGGAGGAACTAAGCAAGTCAACCGAGGCTTGCATGAAAGCAACTTCCACGTTTTGCGCGAGACGCACATGCCAGCGGTACTCCTTGAGCTTGGCTTCATGGATAACGAACGAGAAGCTCTCCTCATGATAAACACAGACTTCCAAAAAGAGTGTGCTCGTGAGATTGCTCAAGGGATTTGCGAATACTTTGGGGTGAAATATGTCCCAGAGAAAAAAGCCAACCCTCCAAAAACAACAACTCCAACGAAAACATTCTACCGAGTTGTTACTGGCTCATTTAAGGAAAAAGCTAATGCAGAGCGCAGAGTTGCTGAATTAAAGCGCAAAGGTTTTGACAGCTTCATTGACTATAAAAATGGCTGGTATAGAGTCATTACTGGCTCTTTCCAAGATAGAGGAAACGCTAAAAAGCGTATGGCAGAACTCAAGCGAGCTGGATTTGATAGCTTCCTTGAAAGCCACAAAGCATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042834 peptidoglycan binding molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7cnpE) rather than this protein.
PDB ID
7cnpE
Method AlphaFoldv2
Resolution 86.04
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50