Protein

Protein accession
A0A6B7LIA2 [UniProt]
Representative
K5Pz
Source
UniProt (cluster: phalp2_22433)
Protein name
Lytic enzyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MINANVISKGTGCSMDVAEEWVDPFKQACEHYGIKSKNAIAALLANVGVETGSLKTFVENLNYSAQGLANTWPSRYSASGRFGGAPNSLALSIARKPMEIANNTYANRMGNGSVASGDGWKYRGRGAIQLTGKANYAEYSKQSGYDALNNPDILTEPKYIADSAAWFFKNSGCIPLADAGAFDSTVKRINGAAPNTANHGDLRRKRYKDALAVV
Physico‐chemical
properties
protein length:214 AA
molecular weight:22882,4 Da
isoelectric point:9,18
hydropathy:-0,37
Representative Protein Details
Accession
K5Pz
Protein name
K5Pz
Sequence length
271 AA
Molecular weight
30137,56440 Da
Isoelectric point
8,67082
Sequence
MNVENWKQILSKAGCGLKEATAWAPHFVKHLNGSRINNPKRVAAFVANLVVESNYLRTVRENLNYSAQGLANTWPKRFSASGLPKGKPNALAVSIARKPKDIANHTYANRMGNGGPETGDGWKHAGKGPIQITGKDNYQQFFKAAGLPADTDPNKLLEPDLGLASAVWYWNAVKANDYIDRNDFDGVCDIINIGRKTRAKGDAHGYNARYNVYSRLLTWLTTYTKLIDSDQRQAVLSIREMESVTPPEITYLEEDPLGEIAVESVQDYEQL
Other Proteins in cluster: phalp2_22433
Total (incl. this protein): 97 Avg length: 241,9 Avg pI: 8,50
Protein ID Length (AA) pI
K5Pz 271 8,67082
1kqoU 227 8,66863
2EVo1 187 5,29293
2JmR 208 8,96815
36lxM 244 9,22028
3P5Uo 336 8,67185
3yZED 206 4,35923
46mT6 320 8,62608
49zNS 215 8,07726
4LuVs 227 6,32393
4U2Ix 305 9,95922
4asLN 211 9,14266
4bgrk 215 9,14266
4kvNk 209 7,73280
50Ney 158 9,83493
50xmf 232 9,55739
5B6jN 185 8,37917
5PDl1 271 8,68262
5PrqG 271 8,69319
5Q9dW 268 8,42868
5aerp 233 9,70792
5bLAr 230 9,08683
5cRPz 226 9,86664
5fW8P 226 9,55674
5ogB6 224 8,50017
5uCSn 233 9,55062
5uDdw 230 9,55668
5uHzK 230 9,61141
5wpLl 226 9,61141
5zfMg 233 9,98224
69mFu 268 7,58951
6DxWe 228 8,71272
6E1Bt 228 8,29607
6Ettv 219 6,90380
6Ft8W 228 8,36569
6KGfi 231 8,41121
6S0hV 235 8,88640
6d3uy 268 8,42777
6kKTY 268 8,42868
6p2TB 268 8,12020
70wDt 268 7,59218
76oIL 208 9,78168
7FrQ2 301 7,54034
7M5JS 271 8,65960
7M7dB 270 7,04601
7MJn8 271 8,33803
7MYSk 270 7,64595
7MkYB 268 8,13322
7ONmd 270 7,00384
7OVnL 268 6,89800
7Omck 270 7,66357
7Oxja 268 7,59218
7P3Ik 270 7,04618
7Vq6y 199 9,34103
7VvYJ 214 8,82400
7ZKyp 268 7,59218
7h5GS 208 9,46314
7h5YU 215 9,69561
7rJgg 235 11,18412
7uUVJ 207 9,46320
7vFSF 326 8,77339
7xRUB 228 8,27492
83dqX 308 5,75202
8aeMp 222 9,37649
8ccF0 262 10,20510
8kyy7 193 9,65003
ClKK 270 6,59784
Htnd 270 7,00333
K8Kd 268 7,59218
KMaD 271 8,69338
Nxbn 268 7,59218
OaAO 270 8,19550
OhH1 270 8,20156
oBrs 270 8,19556
wGbd 268 7,58951
wLoP 270 7,00065
yd5r 227 8,66863
A0A3S7L8K0 235 9,70805
A0A482MV99 200 9,37230
I7ATQ5 214 9,40131
A1YZZ8 218 6,29079
A0A2S1GSQ6 235 9,65925
A0A386KJF2 214 9,29932
A0A482MUT9 200 9,39261
A0A494RAL2 214 9,40131
A0A5B9N6M8 214 9,40131
A0A7S6R7C9 217 6,41135
A0A858NQI8 258 10,02698
A0A858NQY8 258 10,02698
A0A889IQG6 217 6,26925
A0A8S5NZD8 270 7,04601
A0A8S5USG2 267 8,21567
A0A9E7RZL2 214 9,40131
A0A9E9FVT7 214 9,40157
A0A9X9JTH5 214 9,40157
A0AAE9V866 200 9,39254
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_37433
2Fv3r
 11643 37,1% 199 2.680E-75
2 phalp2_5234
8cPFI
 3482 38,1% 220 2.176E-73
3 phalp2_1820
3er8S
 16 35,3% 218 1.045E-69
4 phalp2_33370
6IDED
 552 35,9% 217 1.041E-66
5 phalp2_24275
3cumx
 91 37,1% 199 1.950E-66
6 phalp2_39259
3ZvQn
 35 37,1% 191 4.997E-66
7 phalp2_10067
7wmbf
 22 36,4% 203 2.648E-63
8 phalp2_2766
23eb
 36 37,6% 186 7.471E-61
9 phalp2_36134
6NUh4
 42 38,5% 166 6.700E-60
10 phalp2_28210
jj2c
 60 33,8% 201 9.862E-55

Domains

Domains [InterPro]
Unannotated
Disordered region
Representative sequence (used for alignment): K5Pz (271 AA)
Member sequence: A0A6B7LIA2 (214 AA)
1 271 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage vB_Eco4M-7
[NCBI] 		2601674 Wifcevirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN176217 [NCBI]
CDS location
range 43499 -> 44143
strand +
CDS
ATGATTAATGCAAACGTAATATCTAAAGGGACCGGATGCAGCATGGATGTCGCAGAGGAGTGGGTGGACCCTTTCAAGCAGGCTTGTGAGCACTACGGAATCAAAAGCAAGAATGCCATCGCGGCGCTGCTTGCAAACGTAGGAGTGGAAACAGGCAGTCTGAAGACCTTTGTGGAAAACTTGAACTACTCCGCTCAAGGTCTTGCGAATACATGGCCTAGCCGTTACAGCGCCAGCGGTCGTTTCGGCGGCGCACCAAACTCCTTGGCACTGTCGATTGCCCGTAAACCAATGGAAATCGCCAATAATACATATGCAAACCGAATGGGCAATGGTTCGGTAGCATCTGGCGACGGTTGGAAGTACCGTGGCCGTGGTGCCATTCAGCTGACTGGAAAGGCCAACTATGCAGAGTATTCAAAGCAATCAGGGTATGACGCATTGAATAACCCTGACATTTTGACTGAGCCGAAATACATCGCTGACAGCGCGGCATGGTTTTTCAAGAACAGCGGTTGCATTCCACTTGCTGATGCTGGCGCATTTGATTCGACTGTGAAGCGGATTAACGGGGCCGCGCCAAATACGGCTAACCATGGGGATTTGCGACGGAAGCGTTACAAGGATGCACTAGCAGTTGTGTAA

Gene Ontology

Description Category Evidence (source)
GO:0004568 chitinase activity molecular function None (UniProt)
GO:0006032 chitin catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0A6B7LIA2
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (K5Pz) rather than this protein.
PDB ID
K5Pz
Method AlphaFoldv2
Resolution 91.12
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50