Protein

Protein accession
A0A649VPH1 [UniProt]
Representative
7y5mT
Source
UniProt (cluster: phalp2_2750)
Protein name
lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTIFGVDVSEWQNGMSLRRAKDEGIQFAIIRTNDGTYADRFYLSHLQDAENAGLLTAAYIYLRNPNEGSSIERQVQTTLNVMGNSRRPIWLDCETNAGLHPDHIREAKRRFEAAGVHVPGAYSYVPWWEGKVVGGEPDSHEFGKFWVAAYGRNASGSPKDIYPGDNHYQWAYPVGNQLPVLWQFGSNASVAGFSVDINAFKGSVEELRAIFYGIEGDTTNKEEPELSNQQVEAINAHTRAFITGYLGPQIDAIQDIWQQLRGRNAQGWPQLGQNEQGQNLSLVDGVGAIRQDNADIAKRLDAIEARLDSIDGGK
Physico‐chemical
properties
protein length:314 AA
molecular weight:34871,1 Da
isoelectric point:5,06
hydropathy:-0,52
Representative Protein Details
Accession
7y5mT
Protein name
7y5mT
Sequence length
536 AA
Molecular weight
58107,77090 Da
Isoelectric point
6,38679
Sequence
LEKILPYSRNQVKQDTYYNCGPASSQNVILAATGKTIPESALAAGLGTTVNGTDYIGQFPRVLNAHIPGAAYKHRDVGTYPNAALKDVMWREMTGSINAGHGVIINIVAPPSNYPRAVAPSTESPRYGGGVVYHYIAALGYSDQGGRKLWIADSGFAPYGYWVSFDQICTLIVPKGYAYSTAGAKHPPAPVEHKPQAAGHILGIDISSWQNGMPLSRAKREGMEFVIVRTTDGTYRDTCYRSHILDAEQHGLLTMAYHYLRNPNEGSSIAQQVNTALDVMGDLKRPIWLDCETPAGLHVNHIREAKRLFEAAGVRVIGAYSYVPYWEGKIAPGEPATHEFGAFWVAAYGSNPDGSPSQVYAARGGDNAAQWNYPLGNQKPVLWQYGSKAEVAGFADVDVNAFRGTREDLQALITGKPTLKKEELELSNIDQKRIKLTLDQLAGPGTNSKGEPTFNGWSFDSVLAAAKKKQAANSGLTMVEMLVLNIDAQGKRADATDEALRALNESFTELIKAVGILNQTVEALADNKDPISPEVQ
Other Proteins in cluster: phalp2_2750
Total (incl. this protein): 4 Avg length: 479,0 Avg pI: 6,28
Protein ID Length (AA) pI
7y5mT 536 6,38679
5Mfcm 530 6,83696
8dVPp 536 6,84077
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_10481
415Yr
 125 57,8% 342 7.083E-132
2 phalp2_7112
2kJEw
 1 27,2% 345 4.000E-17

Domains

Domains [InterPro]
PET_C39
GH25
Unannotated
Representative sequence (used for alignment): 7y5mT (536 AA)
Member sequence: A0A649VPH1 (314 AA)
1 536 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183, PF13529

Taxonomy

  Name Taxonomy ID Lineage
Phage Corynebacterium phage EmiRose
[NCBI] 		2565372 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN586033 [NCBI]
CDS location
range 16417 -> 17361
strand +
CDS
ATGACGATATTCGGAGTGGACGTTAGCGAGTGGCAGAATGGCATGTCACTACGCCGCGCTAAAGACGAGGGCATACAATTCGCCATTATCCGCACCAACGACGGCACCTATGCCGACCGCTTCTACCTATCCCACCTGCAGGACGCCGAGAATGCGGGCCTACTAACGGCCGCGTACATTTACTTGCGCAATCCTAACGAGGGTAGTTCCATCGAGAGGCAGGTGCAGACCACGCTAAATGTGATGGGCAATTCCCGCCGCCCTATTTGGCTCGACTGTGAGACTAACGCCGGGCTTCACCCCGACCATATTCGGGAGGCTAAGCGCCGCTTCGAGGCCGCCGGGGTACATGTGCCTGGCGCGTATTCGTATGTTCCATGGTGGGAGGGCAAAGTCGTGGGAGGGGAACCAGATAGCCATGAGTTTGGCAAGTTCTGGGTCGCCGCCTATGGGCGTAATGCCAGCGGATCGCCTAAGGATATCTACCCGGGAGATAACCACTACCAGTGGGCATATCCGGTAGGTAATCAACTTCCAGTACTTTGGCAGTTTGGGAGCAATGCCAGCGTTGCCGGGTTCAGTGTGGATATCAACGCATTTAAGGGGAGCGTAGAGGAACTACGCGCCATTTTCTACGGTATCGAGGGCGATACCACCAACAAGGAGGAACCAGAATTGTCTAACCAGCAGGTAGAGGCCATTAACGCGCATACCCGAGCGTTCATCACGGGCTATTTAGGCCCTCAAATTGACGCTATCCAGGATATTTGGCAGCAACTTCGAGGCAGGAATGCACAGGGCTGGCCACAGCTCGGCCAGAACGAACAGGGACAGAACCTAAGCCTCGTGGACGGGGTAGGAGCAATTCGGCAGGATAACGCCGATATCGCTAAGCGCCTTGACGCTATCGAGGCCCGGCTAGATTCTATCGACGGAGGTAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0003796 lysozyme activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016052 carbohydrate catabolic process biological process None (UniProt)
GO:0016998 cell wall macromolecule catabolic process biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.2.1.17 None Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. match to sequence model evidence used in automatic assertion
ECO:ECO:0000256 		ARBA:ARBA00000632

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7y5mT) rather than this protein.
PDB ID
7y5mT
Method AlphaFoldv2
Resolution 83.61
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50