Protein

Protein accession
A0A649VK21 [UniProt]
Representative
3T2Xl
Source
UniProt (cluster: phalp2_34828)
Protein name
Lysin A
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MADFVWRDGQRLTAWMLYVITLLDIDLFRIFGVHVIVSSGIRTYAEQEAIFRSRYVTAGNVNGRYVYDTRWWNGVLWYRISSAGTVAVPGTSNHEIQGSKAAVDLRDTGRDAGIATAGSARSNWLRANAGAYGLIASGFSFNEAWHYDVPNIWTPVPTPKPPAPTPEPEPEPTLEELMALKSAVIIKNVAAEGYPATALDFAEGFKTSWQADVKYSQTMGVILTEGGPVIITASHYDRIMSDFDAFFKARHERERELARLAGGTAEA
Physico‐chemical
properties
protein length:267 AA
molecular weight:29465,9 Da
isoelectric point:5,59
hydropathy:-0,15
Representative Protein Details
Accession
3T2Xl
Protein name
3T2Xl
Sequence length
267 AA
Molecular weight
29119,37200 Da
Isoelectric point
9,46578
Sequence
MVTFVERDGQRVTPWMAYCIDRLSADMHSLFGVWVRVRSAIRTYEDQKRIFLERYVTAGDVNGRRVYDTRWWNGRLWYRISSAGTVAVPGTSNHEIQGSKAAVDLYDTGSDGGIATMGSARSNWLRANAWKYGLVASGFGFGEAWHYDVLNIFNAVPGKPAGGGTSTPANPKRKKRNMSTGVIHTDDKSDSKRSGAIVDFEAGTFSPFGWFSVAYANGVAKGFGLEASGPVTRGHYDAIKATVAARAAAMGKVFVDIADEDVPQIKS
Other Proteins in cluster: phalp2_34828
Total (incl. this protein): 16 Avg length: 290,3 Avg pI: 8,24
Protein ID Length (AA) pI
3T2Xl 267 9,46578
1Isml 267 4,84560
1hNpF 270 9,31544
1hQJu 258 8,54478
39qrD 289 8,99819
40vZv 256 8,59829
A0A2Z4Q640 313 8,97775
A0A2Z4Q7L4 313 9,17168
A0A2U8UIP4 341 10,11291
A0A481VXF8 308 9,31718
A0A516KPH5 313 9,41311
A0A516KV17 317 6,09481
A0A7G9A0W6 295 7,91860
A0A8F2IGP2 301 9,57679
A0AAE9C3S7 269 5,88343
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_9106
5GTdJ
 17 57,5% 179 2.047E-65
2 phalp2_9597
1rpNz
 3 46,6% 193 1.208E-63
3 phalp2_11793
7YFVa
 3 48,2% 174 1.825E-61
4 phalp2_19567
3V3ST
 4 46,7% 182 3.418E-47
5 phalp2_2372
7Ia0A
 8 44,5% 184 1.012E-42
6 phalp2_15608
2ldH7
 2 28,6% 206 3.242E-15
7 phalp2_16194
4ErvX
 37 22,3% 170 2.755E-04

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 3T2Xl (267 AA)
Member sequence: A0A649VK21 (267 AA)
1 267 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Microbacterium phage Megan
[NCBI] 		2656551 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN586020 [NCBI]
CDS location
range 30874 -> 31677
strand +
CDS
ATGGCTGACTTCGTGTGGCGCGACGGGCAACGCCTGACCGCGTGGATGCTCTACGTCATCACCCTCCTCGACATCGACCTGTTCCGCATCTTCGGCGTGCACGTCATCGTGTCCTCGGGCATCCGCACCTACGCCGAGCAGGAGGCCATCTTCCGCTCGCGCTACGTGACAGCCGGGAACGTCAATGGCCGATACGTCTACGACACCCGATGGTGGAACGGCGTGCTGTGGTATCGCATCTCCAGCGCGGGCACCGTCGCCGTACCGGGCACCTCGAACCACGAGATACAGGGCTCCAAGGCCGCTGTCGATCTGCGCGACACGGGCCGCGACGCCGGGATCGCGACAGCCGGGAGCGCACGCTCCAACTGGCTCCGCGCGAACGCTGGCGCGTATGGCCTCATCGCCTCGGGCTTCTCGTTCAACGAGGCGTGGCACTACGACGTGCCCAACATCTGGACACCCGTACCGACTCCCAAGCCCCCGGCTCCAACACCGGAACCGGAACCCGAGCCGACCCTGGAGGAACTCATGGCTCTCAAGTCCGCAGTCATCATCAAGAACGTCGCCGCCGAAGGCTACCCGGCCACGGCGCTCGACTTTGCCGAGGGGTTCAAGACCTCCTGGCAGGCCGACGTCAAGTACTCGCAGACGATGGGCGTGATCCTCACCGAGGGTGGCCCCGTCATCATCACCGCGAGCCACTACGACCGCATCATGAGCGACTTCGACGCCTTCTTCAAGGCGCGTCACGAGCGCGAGCGTGAACTGGCCCGCCTCGCGGGCGGTACTGCCGAGGCGTGA

Gene Ontology

Description Category Evidence (source)
GO:0006508 proteolysis biological process None (UniProt)
GO:0008233 peptidase activity molecular function None (UniProt)
GO:0016020 membrane cellular component None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3T2Xl) rather than this protein.
PDB ID
3T2Xl
Method AlphaFoldv2
Resolution 79.70
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50