Protein

Protein accession
A0A5P1M7C7 [UniProt]
Representative
7PI88
Source
UniProt (cluster: phalp2_28816)
Protein name
L-alanyl-D-glutamate peptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSFKFGKNSEKQLATVKPELQKVARRALELSPYDFTIVQGIRTVAQSAQNIANGTSFLKDPSKSKHVTGDAIDFAPYINGKIDWKDLEAFWAVKKAFEQAGKELGIKLRFGADWNSSGDYHDEIDRGTYDGGHVELA
Physico‐chemical
properties
protein length:137 AA
molecular weight:15238,9 Da
isoelectric point:6,84
hydropathy:-0,53
Representative Protein Details
Accession
7PI88
Protein name
7PI88
Sequence length
80 AA
Molecular weight
8972,84440 Da
Isoelectric point
5,19874
Sequence
MKDPSKSKHVTGDAIDFAPYINGKIDWKDLEAFWAVKKAFEQAGKELGVKLRFGADWNSSGDYHDEIDRGTYDGGHVELV
Other Proteins in cluster: phalp2_28816
Total (incl. this protein): 86 Avg length: 132,4 Avg pI: 7,11
Protein ID Length (AA) pI
7PI88 80 5,19874
2hlup 59 6,27323
4pCpk 67 5,53347
6SOTQ 69 4,23112
7HREQ 68 4,35201
B2I481 80 5,19874
A0A6M5CBG7 137 8,00441
A0A291LBZ8 137 6,83531
A0A482N860 137 7,92769
I7K2L2 137 7,97069
A0A0A7TY81 137 7,97276
A0A2Z5HTF1 137 7,90900
A0A2Z5HRM4 137 6,28937
A0A6G8RKB0 137 6,28926
A0A6G8RFF4 137 6,83531
A0A162EAZ8 137 8,86016
A0A2U8UWR1 137 7,91474
A0A2K8GPS6 137 6,91341
A0A2H4PGV7 137 6,83196
A0A2H4PIC5 137 7,91474
A0A0A0RPG5 137 6,83531
A0A240FFT1 137 7,92756
A0A249Y2E6 137 6,83531
A0A291LGR9 137 6,91255
A0A291NKX5 137 7,91474
A0A2K8HDL6 137 6,83531
A0A3G2KAW3 137 6,83531
A0A3P4A7X9 137 7,91474
A0A411AVN1 137 6,83531
A0A482N3X6 137 7,91474
A0A482N451 137 7,91474
A0A482N987 137 7,91474
A0A494WIF8 137 7,91474
A0A4D5ZIX2 137 7,98662
A0A4D6T568 137 6,83196
A0A4P8NFP8 137 6,83531
A0A4P8NGK1 137 6,83531
A0A4Y5TN13 137 6,83531
A0A5B8R4C3 137 7,98662
A0A5B8RR54 137 8,77810
A0A5B9NAY0 137 7,98662
A0A5C0CF11 137 6,83531
A0A5C0CH91 137 6,83531
A0A5J6D6C9 137 6,83531
A0A5P1M674 137 6,83531
A0A5P1M7L4 137 6,83531
A0A5P1M870 137 6,83531
A0A5P1M8E2 137 6,83531
A0A5P8PLA2 137 6,83196
A0A5P8PLL2 137 9,12558
A0A6G8QX72 137 7,91474
A0A6G8RCW2 137 6,83531
A0A6G8REC6 137 6,83531
A0A6G8RH41 137 6,83531
A0A6G8RJ94 137 6,83531
A0A6G8RJT6 137 6,83531
A0A6G8RKN5 137 6,41413
A0A6G9L7V8 137 6,83531
A0A7G8AMW0 137 6,83531
A0A7G8ANB6 137 7,91474
A0A7G8ANX8 137 6,83531
A0A7L5CBM1 137 7,91474
A0A7L5CBU3 137 7,91474
A0A7S9XFK3 137 7,91474
A0A7U0G9P0 137 6,83531
M4PUV3 137 6,83531
A0A2D2W6T8 137 6,72993
A0A2P0QDJ2 137 6,83531
A0A2Z5HK95 137 6,83531
A0A3G8F1H7 137 6,83531
A0A514A261 137 6,83531
A0A5C0CF79 137 6,83531
A0A5C0CI63 137 6,83531
A0A6G8QYL6 137 6,83531
A0A6G8RL64 137 6,83531
A0A6G9L7E2 137 6,83531
A0A9E7IHB5 137 6,83531
A0A9E7J886 137 8,83148
A0AAE7SB98 137 7,91474
A0AAE7VT55 137 6,41868
A0AAE7W0E2 137 6,83531
A0AAE9ZFW3 137 8,80350
A0AB33QFU1 137 6,91204
A0AB39BZY3 137 6,83116
A0AB39C193 137 6,83531
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_20976
7wh8L
 317 36,9% 73 3.081E-17
2 phalp2_11313
705Lu
 1 29,8% 57 1.034E-07
3 phalp2_31742
3Vmff
 206 28,5% 77 1.953E-07
4 phalp2_23534
7gs3U
 1 43,6% 55 2.685E-07
5 phalp2_26937
4AYDe
 825 30,8% 81 1.813E-06
6 phalp2_14966
t5aA
 5 31,0% 74 2.492E-06
7 phalp2_35408
boku
 1 30,1% 73 2.314E-05
8 phalp2_25667
4uzhW
 1 25,4% 51 3.181E-05
9 phalp2_22402
x6Pz
 1 33,7% 77 3.181E-05

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 7PI88 (80 AA)
Member sequence: A0A5P1M7C7 (137 AA)
1 80 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Escherichia phage vB_EcoS-26175III
[NCBI] 		2576480 Demerecviridae > Epseptimavirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MK907269 [NCBI]
CDS location
range 11802 -> 12215
strand -
CDS
ATGAGTTTTAAATTTGGTAAAAATAGTGAAAAACAATTAGCAACTGTTAAGCCCGAGCTACAAAAGGTAGCTCGTAGGGCTTTAGAACTATCCCCATACGATTTCACAATCGTACAAGGTATTCGTACAGTAGCACAAAGTGCCCAAAATATTGCTAATGGTACTTCATTCTTGAAAGACCCTAGCAAAAGTAAGCATGTAACTGGAGATGCTATAGATTTTGCACCATATATTAATGGTAAGATTGATTGGAAAGATCTGGAAGCATTTTGGGCTGTTAAGAAGGCTTTTGAACAAGCTGGTAAGGAACTTGGTATCAAACTTCGTTTTGGTGCCGACTGGAATAGTTCTGGTGATTATCATGATGAGATCGATCGTGGTACTTACGACGGTGGTCACGTAGAATTAGCCTGA

Gene Ontology

Description Category Evidence (source)
GO:0008233 peptidase activity molecular function None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.4.24.- None None N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7PI88) rather than this protein.
PDB ID
7PI88
Method AlphaFoldv2
Resolution 96.62
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50