Protein

Protein accession
A0A5J6TDZ2 [UniProt]
Representative
6Udpv
Source
UniProt (cluster: phalp2_20894)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSGREAMVAAMESLLGLGERDGSQNKVQAWYRSRNGSAYSGNFAWCDASITWAAVQSGNYDAVCHGTDFAYTVAHAARFQAKGEWHTDIAGIQRGDIVFFDWAGTNSVGAIDHVGIVTSVSGSTVYTIEGNIGNVCARKVRYSNYIVGYGRPKYAAESKPSGSTGSGSTVKYQPFPGASWFKASPKSSIVTRMGKRLVAEKCSAYKSGPGPQWTTVDKASYQKWQKKLGYTGSDADGWPGKTSWDKLKVPVA
Physico‐chemical
properties
protein length:252 AA
molecular weight:27130,0 Da
isoelectric point:9,39
hydropathy:-0,41
Representative Protein Details
Accession
6Udpv
Protein name
6Udpv
Sequence length
321 AA
Molecular weight
34196,78570 Da
Isoelectric point
5,35289
Sequence
MIAWMIYCIGADETNGNNVNFITHWYGEDGEPWCNMTITYAAWHSGNSQNVCGGTKRDYTVNHAQWFQSRGQWHTDTAGIQRGDIVFFDWNGTNSISAIDHVGIVESVSGSDVHTIEGNIDNVCKRMVRHSNYIVGYGRPKYSTASAPPPPDTTPTPPAAGTDTYTVKAGDTLSAIARSLGVSLDALLAVNPQITNPDEIDVGQVINVPAATDQAPDEPAPAPAPAPTPTPVPPPPYVSLFNLQYAKAHPGAHRSDVLAFQKALARVVGLDYSSGPGIYGPATTAACKKFQQLQGWAGTGTPNFDVLNLLASKTGLLIPAP
Other Proteins in cluster: phalp2_20894
Total (incl. this protein): 9 Avg length: 257,9 Avg pI: 8,98
Protein ID Length (AA) pI
6Udpv 321 5,35289
A0A2Z4QBA7 250 9,42729
A0A2Z4QBI6 248 9,42729
A0A2Z4QC13 252 9,39203
A0A345L2C1 252 9,46449
A0A386KQY2 252 9,46449
A0A5J6TDS6 248 9,42729
A0A9E7SY89 246 9,46468
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13865
7ucym
 2 34,8% 307 2.110E-35
2 phalp2_19951
6Hzjb
 3 30,8% 360 1.113E-24
3 phalp2_20967
7tMqT
 4 31,2% 330 1.242E-23
4 phalp2_29393
1dfbb
 105 34,1% 240 1.124E-21
5 phalp2_26339
1fSIl
 1 28,4% 218 4.398E-19
6 phalp2_36426
XLCr
 2 28,0% 221 1.438E-09

Domains

Domains [InterPro]
CHAP
LysM
PG_1
Representative sequence (used for alignment): 6Udpv (321 AA)
Member sequence: A0A5J6TDZ2 (252 AA)
1 321 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01476, PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Streptomyces phage Intolerant
[NCBI] 		2601642 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN224565 [NCBI]
CDS location
range 27603 -> 28361
strand +
CDS
ATGAGCGGGCGCGAAGCGATGGTGGCCGCCATGGAGTCCCTTCTCGGGCTCGGTGAGCGGGACGGCTCGCAGAACAAGGTGCAGGCGTGGTACCGGTCCCGGAACGGCTCCGCCTACTCGGGGAACTTCGCGTGGTGTGACGCGTCGATCACCTGGGCGGCCGTCCAGTCCGGCAACTACGACGCGGTGTGCCACGGCACGGACTTCGCGTACACCGTGGCCCACGCCGCGCGCTTCCAGGCGAAGGGCGAGTGGCACACGGACATCGCCGGTATCCAGCGCGGGGACATCGTGTTCTTCGACTGGGCGGGCACGAACAGCGTCGGCGCGATCGACCACGTGGGCATCGTGACCTCGGTGAGCGGGTCCACCGTTTACACGATCGAGGGCAACATCGGCAACGTCTGCGCCCGCAAGGTCCGGTACTCGAACTACATCGTCGGCTACGGCCGCCCGAAGTACGCGGCCGAGTCGAAGCCGTCCGGCTCCACCGGCTCCGGCTCCACGGTGAAGTACCAGCCCTTCCCCGGCGCCTCGTGGTTCAAGGCGTCCCCGAAGTCGTCCATCGTGACGCGGATGGGGAAGCGCCTCGTGGCGGAGAAGTGCTCCGCGTACAAGTCGGGCCCCGGCCCGCAGTGGACCACGGTGGACAAGGCGTCGTACCAGAAGTGGCAGAAGAAGCTGGGATACACCGGCTCGGACGCCGACGGCTGGCCCGGCAAGACCTCGTGGGACAAGCTGAAGGTCCCCGTCGCCTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6Udpv) rather than this protein.
PDB ID
6Udpv
Method AlphaFoldv2
Resolution 79.09
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50